" /> Epipodophyllotoxin Compound - CISMeF





Preferred Label : Epipodophyllotoxin Compound;

NCIt related terms : epipodophyllotoxin;

NCIt definition : An alkaloid isolated or derived synthetically from Podophyllum peltatum that can bind to and inhibit topoisomerase II and its function in ligating cleaved DNA molecules, resulting in the accumulation of single- or double-strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of some types of cancer. Epipodophyllotoxin is extracted from the mandrake root Podophyllum peltatum. It is a type of topoisomerase inhibitor.;

Codes from synonyms : CDR0000044822;

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Keyword's position in hierarchy(ies) : arborescence

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28/05/2025


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