Preferred Label : nucleic acid hybridization;
MeSH definition : Widely used technique which exploits the ability of complementary sequences in single-stranded
DNAs or RNAs to pair with each other to form a double helix. Hybridization can take
place between two complimentary DNA sequences, between a single-stranded DNA and a
complementary RNA, or between two RNA sequences. The technique is used to detect and
isolate specific sequences, measure homology, or define other characteristics of one
or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503);
MeSH synonym : acid hybridization, nucleic; hybridization, nucleic acid; hybridizations, nucleic acid; nucleic acid hybridizations; acid hybridizations, nucleic;
MeSH Hyperonym : genomic hybridization; Genomic Hybridizations; Hybridization, Genomic; Hybridizations, Genomic;
MeSH annotation : IM general only; coord NIM with DNA or RNA or specific (IM); IN SITU HYBRIDIZATION
& IN SITU HYBRIDIZATION, FLUORESCENCE are available;
Origin ID : D009693;
UMLS CUI : C1300517;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
Widely used technique which exploits the ability of complementary sequences in single-stranded
DNAs or RNAs to pair with each other to form a double helix. Hybridization can take
place between two complimentary DNA sequences, between a single-stranded DNA and a
complementary RNA, or between two RNA sequences. The technique is used to detect and
isolate specific sequences, measure homology, or define other characteristics of one
or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
http://sogc.org/wp-content/uploads/2013/02/gui270TU1112F.pdf
http://www.jogc.com/article/S1701-2163%2816%2935113-1/abstract
10.1016/S1701-2163(16)35113-1
2011
false
Canada
French
prenatal diagnosis
nucleic acid hybridization
guideline
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