Preferred Label : oligonucleotide probes;
MeSH definition : Synthetic or natural oligonucleotides used in hybridization studies in order to identify
and study specific nucleic acid fragments, e.g., DNA segments near or within a specific
gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional
techniques used for testing for the hybridization product include dot blot assays,
Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels
for the probe include the radioisotope labels 32P and 125I and the chemical label
biotin.;
MeSH synonym : probes, oligonucleotide; Oligonucleotide Probe; Probe, Oligonucleotide;
MeSH hyponym : oligodeoxyribonucleotide probes; oligoribonucleotide probes; Probes, Oligodeoxyribonucleotide; Probes, Oligoribonucleotide;
MeSH annotation : usually no qualif; /drug eff /ultrastruct permitted;
Is substance : O;
Origin ID : D015345;
UMLS CUI : C0028952;
Allowable qualifiers
- Indexing information
- Record concept(s)
- See also
- Semantic type(s)
Synthetic or natural oligonucleotides used in hybridization studies in order to identify
and study specific nucleic acid fragments, e.g., DNA segments near or within a specific
gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional
techniques used for testing for the hybridization product include dot blot assays,
Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels
for the probe include the radioisotope labels 32P and 125I and the chemical label
biotin.
