mitotane - CISMeF

Preferred Label : mitotane;

MeSH definition : A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.;

MeSH synonym : o,p-ddd; ortho,para ddd; ortho,para-ddd; mytotan;

CISMeF synonym : Bristol-Myers squibb brand of mitotane; bristol myers squibb brand of mitotane;

MeSH hyponym : chlodithane; chloditan; lysodren; Khloditan;

MeSH CAS label : benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-;

MeSH Related Number : 53-19-0 (Mitotane);

Registry Number MeSH : 53-19-0;

MeSH annotation : TN 111 for eff on insects;

Wikipedia link : https://en.wikipedia.org/wiki/Mitotane;

Codes EINECS : 200-166-6;

Is substance : O;

UNII : 78E4J5IB5J;

InChIKey : JWBOIMRXGHLCPP-UHFFFAOYSA-N;

Details

Origin ID

D008939;

UMLS CUI

C0026256;

ATC code(s)
- mitotane [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- mitotane [Substance BNPC]
Currated CISMeF NLP mapping
- Mitotane [ICD-11 Extension code]
- Mitotane [LOINC component]
- Mitotane [ICHI extension code]
- Mitotane [SMS substance]
- Mitotane [NCIt concept]
- Mitotane (substance) [SNOMED CT concept]
- mitotane [SNOMED Notion]
Pharmacological action(s)
- antineoplastic agents, hormonal [MeSH Descriptor]
Record concept(s)
- chloditan [MeSH concept]
- chlodithane [MeSH concept]
- lysodren [MeSH concept]
- mitotane [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(2-chlorophenyl)-1-(4-iodophenyl)-2,2-dichloroethane [MeSH Supplementary Concept]
- 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene [MeSH Supplementary Concept]
- 2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid [MeSH Supplementary Concept]
- 2-(4-chlorophenyl)-2-(4-chloro-3-thiophenol)-1,1-dichlorethene [MeSH Supplementary Concept]
- mitometh [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mitotane [ICD-11 Extension code]
- Mitotane [NCIt concept]
- Mitotane [LOINC component]
- Mitotane (substance) [SNOMED CT concept]
- Product containing mitotane (medicinal product) [SNOMED CT concept]
- mitotane [ATC Code]
- mitotane [Substance BNPC]
- mitotane [SNOMED Notion]
- o,p'- DDD [LOINC component]
Validated automatic mappings to BTNT
- mitotane [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients