" /> Mitotane - CISMeF





Preferred Label : Mitotane;

NCIt synonyms : Mytotan; 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; DDD; 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane; o,p'-DDD; Ortho,para-DDD; 2,4'-Dichlorodiphenyldichloroethane; 2,2-Bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane; o,p' - DDD; Khloditan;

NCIt related terms : CB 313; 1, 1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; Chloditan; 2, 2-Bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane; Lysodren; Chlodithane; Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro-; 1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene; 2, 4'-Dichlorodiphenyldichloroethane; (o,p)-DDD;

NCIt definition : A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in the adrenal cortex to a reactive acyl chloride intermediate, mitotane covalently binds to adrenal proteins, specifically inhibiting adrenal cortical hormone production. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug used in treating adrenocortical cancer and ACTH-producing pituitary tumors (Cushing's disease).;

UNII : 78E4J5IB5J;

InChIKey : JWBOIMRXGHLCPP-UHFFFAOYSA-N;

CAS number : 53-19-0;

Drug name : Lisodren; Lysodren;

Molecule name : CB-313; WR-13045;

Chemical formula : C14H10Cl4;

NSC code : 38721;

Codes from synonyms : 07096; NSC0038721; CDR0000045227; 335;

Details


You can consult :


Nous contacter.
28/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.