lysosomes - CISMeF

Preferred Label : lysosomes;

MeSH definition : A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed); A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed); A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed).;

MeSH synonym : lysosome;

Related MeSH term : Autolysosome;

MeSH annotation : A 11 qualif except /cytol; /genet permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Lysosome;

Details

Origin ID

D008247;

UMLS CUI

C0024369;

Allowable qualifiers
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- transplantation [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- virology [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Autolysosome [FMA entity]
- Autolysosome (cell structure) [SNOMED CT concept]
- Autophagolysosome [NCIt concept]
- Lysosome [FMA entity]
- Lysosome [LOINC component]
- Lysosome Assembly Pathway [NCIt concept]
- autolysosome [GO term]
- lysosome [GO term]
Currated CISMeF NLP mapping
- Lysosome [NCIt concept]
- Lysosome (cell structure) [SNOMED CT concept]
- lysosome, nos [SNOMED Notion]
Indexing information
- Kif2b protein, mouse [MeSH Supplementary Concept]
- Laptm5 protein, rat [MeSH Supplementary Concept]
- Lgp107 protein, rat [MeSH Supplementary Concept]
- NCU-G1 protein, mouse [MeSH Supplementary Concept]
- SCARB2 protein, human [MeSH Supplementary Concept]
- WDR48 protein, human [MeSH Supplementary Concept]
- lysosomal proteins [MeSH Supplementary Concept]
Record concept(s)
- Autolysosomes [MeSH concept]
- lysosomes [MeSH concept]
Semantic type(s)
- Cell Component [UMLS semantic type]
UMLS correspondences (same concept)
- Lysosome [LOINC component]
- Lysosome [FMA entity]
- Lysosome [NCIt concept]
- Lysosome (cell structure) [SNOMED CT concept]
- lysosome [GO term]
- lysosome, nos [SNOMED Notion]

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A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured or undergoes MEMBRANE FUSION. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed).