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Preferred Label : kininogens;

MeSH definition : Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.;

MeSH synonym : prekinins; cystatins, kininogen; prokinins; kininogen cystatins;

MeSH hyponym : thiostatin; kininogen; T-Kininogen; T Kininogen;

MeSH annotation : cysteine proteinase inhib; /drug eff /physiol permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Kininogens;

Is substance : O;

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Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.

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27/10/2024


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