MeSH definition : Endogenous peptides present in most body fluids. Certain enzymes convert them to active
KININS which are involved in inflammation, blood clotting, complement reactions, etc.
Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors.
HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce
BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein
to produce KALLIDIN.;
Endogenous peptides present in most body fluids. Certain enzymes convert them to active
KININS which are involved in inflammation, blood clotting, complement reactions, etc.
Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors.
HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce
BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein
to produce KALLIDIN.