iduronate sulfatase

Preferred Label : iduronate sulfatase;

MeSH definition : An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.;

MeSH synonym : sulfate sulfatase, iduronate; iduronatesulfate sulfohydrolase; hunter corrective factor; sulfoiduronate sulfatase; factor, hunter corrective; iduronate sulfate sulfatase; sulfohydrolase, iduronatesulfate; sulfatase, sulfoiduronate; corrective factor, hunter; sulfatase, iduronate; sulfatase, iduronate sulfate;

MeSH CAS label : L-Iduronate-2-sulfate 2-sulfohydrolase;

Registry Number MeSH : EC 3.1.6.13;

Is substance : O;

UNII : EC 3.1.6.13;

Details

Origin ID

D007066;

UMLS CUI

C0020814;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Iduronate 2-Sulfatase [NCIt concept]
- Iduronate-2-Sulfatase [LOINC component]
- iduronate 2-sulfatase [SNOMED Notion]
Record concept(s)
- iduronate sulfatase [MeSH concept]
Related MeSH Supplementary Concept(s)
- Ids protein, mouse [MeSH Supplementary Concept]
- idursulfase [MeSH Supplementary Concept]
- idursulfase beta, mouse [MeSH Supplementary Concept]
Related MeSH term(s)
- mucopolysaccharidosis ii [MeSH Descriptor]
See also
- mucopolysaccharidosis ii [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Iduronate-2-Sulfatase [LOINC component]
- Idursulfase (substance) [SNOMED CT concept]
- Product containing idursulfase (medicinal product) [SNOMED CT concept]
- iduronate 2-sulfatase [SNOMED Notion]
Validated automatic mappings to BTNT
- Idursulfase [NCIt concept]
- Idursulfase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients