Preferred Label : iduronate sulfatase;
MeSH definition : An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency
has been demonstrated in Hunter's syndrome, which is characterized by an excess of
dermatan sulfate and heparan sulfate. EC 3.1.6.13.;
MeSH synonym : sulfate sulfatase, iduronate; iduronatesulfate sulfohydrolase; hunter corrective factor; sulfoiduronate sulfatase; factor, hunter corrective; iduronate sulfate sulfatase; sulfohydrolase, iduronatesulfate; sulfatase, sulfoiduronate; corrective factor, hunter; sulfatase, iduronate; sulfatase, iduronate sulfate;
MeSH CAS label : L-Iduronate-2-sulfate 2-sulfohydrolase;
Registry Number MeSH : EC 3.1.6.13;
Is substance : O;
UNII : EC 3.1.6.13;
Origin ID : D007066;
UMLS CUI : C0020814;
Allowable qualifiers
Currated CISMeF NLP mapping
Record concept(s)
Related MeSH Supplementary Concept(s)
Related MeSH term(s)
See also
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency
has been demonstrated in Hunter's syndrome, which is characterized by an excess of
dermatan sulfate and heparan sulfate. EC 3.1.6.13.
http://www.has-sante.fr/portail/jcms/c_2048976/fr/elaprase
http://www.has-sante.fr/portail/jcms/c_517668/fr/elaprase
2015
false
France
French
treatment outcome
enzyme replacement therapy
iduronate sulfatase
mucopolysaccharidosis ii
infusions, intravenous
orphan drug production
idursulfase
idursulfase
evaluation of the transparency committee
---
http://www.cochrane.org/fr/CD008185
2014
false
true
false
United Kingdom
France
iduronate sulfatase
treatment outcome
review of literature
french abstract
mucopolysaccharidosis ii
enzyme replacement therapy
---
https://www.ema.europa.eu/medicines/human/EPAR/Elaprase
2012
United Kingdom
French
English
syndication feed
Contraindications, Procedure
mucopolysaccharidosis ii
treatment outcome
iduronate sulfatase
iduronate sulfatase
drug evaluation, preclinical
iduronate sulfatase
iduronate sulfatase
iduronate sulfatase
drug interactions
pregnancy
breast feeding
drug labeling
drug approval
orphan drug production
infusions, intravenous
adult
child
adolescent
drug storage
drug compounding
iduronate sulfatase
iduronate sulfatase
idursulfase
idursulfase
iduronate sulfatase
drug evaluation
package leaflet
summary of product characteristics
Contraindications, Drug
---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=217085
2011
France
scientific and technical information
patients
iduronate sulfatase
mucopolysaccharidosis ii
mucopolysaccharidoses
---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=217093
2011
France
scientific and technical information
iduronate sulfatase
mucopolysaccharidoses
patients
mucopolysaccharidosis ii
---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Elaprase_Dec-19-2007_f.pdf
2007
Canada
French
canada
insurance, health, reimbursement
iduronate sulfatase
mucopolysaccharidosis ii
idursulfase
idursulfase
iduronate sulfatase
drug evaluation
---