MeSH definition : Conditions of abnormal THYROID HORMONES release in patients with apparently normal
THYROID GLAND during severe systemic illness, physical TRAUMA, and psychiatric disturbances.
It can be caused by the loss of endogenous hypothalamic input or by exogenous drug
effects. The most common abnormality results in low T3 THYROID HORMONE with progressive
decrease in THYROXINE; (T4) and TSH. Elevated T4 with normal T3 may be seen in diseases
in which THYROXINE-BINDING GLOBULIN synthesis and release are increased.;
MeSH hyponym : low T3-Low T4 syndrome; low T3 syndrome; low T3-High T4 syndrome; high T4 syndrome; Low T3 Low T4 Syndrome; Low T3 and Low T4 Syndrome; Low T3 High T4 Syndrome; High T4 Syndromes;
MeSH annotation : differentiate from THYROID HORMONE RESISTANCE SYNDROME where no other disease is present;
Conditions of abnormal THYROID HORMONES release in patients with apparently normal
THYROID GLAND during severe systemic illness, physical TRAUMA, and psychiatric disturbances.
It can be caused by the loss of endogenous hypothalamic input or by exogenous drug
effects. The most common abnormality results in low T3 THYROID HORMONE with progressive
decrease in THYROXINE; (T4) and TSH. Elevated T4 with normal T3 may be seen in diseases
in which THYROXINE-BINDING GLOBULIN synthesis and release are increased.