microbial collagenase

Preferred Label : microbial collagenase;

MeSH definition : A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.;

MeSH synonym : collalysine; collagenase, clostridium histolyticum; collagenase, microbial; nucleolysin; clostridiopeptidase a; clostridium histolyticum collagenase; Collagenase Clostridium histolyticum; Clostridium histolyticum, Collagenase; histolyticum, Collagenase Clostridium;

MeSH Hyperonym : Collagenase-Like peptidase; Collagenase Like Peptidase; Peptidase, Collagenase-Like;

Registry Number MeSH : EC 3.4.24.3;

MeSH annotation : coord IM with specific bacterium /enzymol (IM or NIM) if pertinent;

Wikipedia link : https://en.wikipedia.org/wiki/Microbial collagenase;

Is substance : O;

UNII : EC 3.4.24.3;

Details

Origin ID

D003012;

UMLS CUI

C0009053;

ATC code(s)
- collagenase clostridium histolyticum [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Collagenase clostridium histolyticum [ICD-11 Extension code]
Indexing information
- (5-cinnamido-4-oxo-6-phenylhexanoyl)prolyl-proline [MeSH Supplementary Concept]
- cinnamido-2-methyl-5-oxoheptanoyl-prolyl-arginine [MeSH Supplementary Concept]
- prolyl-leucyl-alanine hydroxamic acid [MeSH Supplementary Concept]
Record concept(s)
- Collagenase-Like peptidase [MeSH concept]
- microbial collagenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- collagenase VII-S, clostridium histolyticum [MeSH Supplementary Concept]
- iruxol [MeSH Supplementary Concept]
- kappa-toxin, clostridium perfringens [MeSH Supplementary Concept]
- type V collagen-degrading enzyme [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing Clostridium histolyticum collagenase (medicinal product) [SNOMED CT concept]
- obsolete microbial collagenase activity [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Clostridium histolyticum collagenase (substance) [SNOMED CT concept]
- Product containing Clostridium histolyticum collagenase (medicinal product) [SNOMED CT concept]
- clostridium histolyticum collagenase [SNOMED Notion]
- collagenase clostridium histolyticum [ATC Code]
Validated automatic mappings to NTBT
- Collagenase [LOINC component]
- Collagenase [NCIt concept]
- collagenase [ATC Code]
- collagenase [Substance BNPC]

Keyword's position in hierarchy(ies) :

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