Preferred Label : Collagenase Clostridium histolyticum;
NCIt synonyms : CCH EN3835; C. Clostridium histolyticum EN3835; Collagenase Clostridium histolyticum EN3835;
NCIt definition : A therapeutic enzyme produced by the bacterium Clostridium histolyticum, with enzymatic
debriding activity. Upon injection of collagenase clostridium histolyticum to the
affected area(s), the collagenase hydrolyzes collagen in the collagen triple helix
structure resulting in lysis and solubilization of collagen deposits and plaques.
This may promote healing and reduce symptoms caused by excessive collagen deposits
and accumulation, such as stiffness of the tissue and pain.;
UNII : 9X7O8V25IT;
CAS number : 9001-12-1;
Drug name : Xiaflex;
Molecule name : EN-3835; EN 3835;
NCI Metathesaurus CUI : CL1778268;
Origin ID : C185860;
UMLS CUI : C5667027;
Semantic type(s)
- concept_is_in_subset
