Preferred Label : chlorhexidine;
MeSH definition : A disinfectant and topical anti-infective agent used also as mouthwash to prevent
oral plaque.;
CISMeF synonym : A, sebidin;
MeSH hyponym : novalsan; chlorhexidine hydrochloride; MK-412A; tubulicid; chlorhexidine acetate; sebidin A; Hydrochloride, Chlorhexidine; Acetate, Chlorhexidine; MK 412A; MK412A;
MeSH CAS label : 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-;
MeSH Related Number : chlorhexidine hydrochloride; 3697-42-5 (Chlorhexidine hydrochloride); 55-56-1 (Chlorhexidine); chlorhexidine acetate; 5908ZUF22Y; E64XL9U38K;
Registry Number MeSH : 55-56-1;
Related CAS MeSH : E64XL9U38K (Chlorhexidine hydrochloride); 5908ZUF22Y (Chlorhexidine acetate);
Wikipedia link : https://en.wikipedia.org/wiki/Chlorhexidine;
Codes EINECS : 200-238-7;
Is substance : O;
UNII : R4KO0DY52L;
InChIKey : GHXZTYHSJHQHIJ-UHFFFAOYSA-N;
Origin ID : D002710;
UMLS CUI : C0008196;
ATC code(s)
ATC code(s)
Allowable qualifiers
CISMeF manual mappings
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- V 3703 [MeSH Supplementary Concept]
- flexsol [MeSH Supplementary Concept]
- hydrex [MeSH Supplementary Concept]
- lurgyl [MeSH Supplementary Concept]
- savlon [MeSH Supplementary Concept]
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A disinfectant and topical anti-infective agent used also as mouthwash to prevent
oral plaque.
https://www.has-sante.fr/jcms/p_3538263/fr/chlorhexidine-liberty-pharma-chlorhexidine-anti-infectieux-pour-traitement-oral-local
2024
false
false
false
France
treatment outcome
insurance, health, reimbursement
chlorhexidine gluconate
mouthwashes
chlorhexidine
gingivitis
periodontitis
oral surgical procedures
preoperative care
postoperative care
evaluation of the transparency committee
administration, topical
anti-infective agents, local
chlorhexidine
---
https://www.has-sante.fr/jcms/p_3540394/fr/chloraprep-gluconate-de-chlorhexidine-/-alcool-isopropylique-antisepsie
2024
false
false
false
France
drug combinations
insurance, health, reimbursement
administration, cutaneous
Impregnated cutaneous swab
Preoperative disinfection of skin (procedure)
evaluation of the transparency committee
antisepsis
2-Propanol
chlorhexidine gluconate
chlorhexidine
---
https://www.cochrane.org/fr/CD013841/NEONATAL_chlorhexidine-ou-autres-solutions-antiseptiques-laquelle-est-la-plus-efficace-pour-prevenir-les
2023
United Kingdom
review of literature
french abstract
Catheter-Related infections
solution, nos
Antiseptics
newborn, nos
solutions
attentiveness
infectious disease, nos
Solutions
infant, newborn
anti-infective agents, local
catheter, nos
chlorhexidine
Infectious disease
chlorhexidine
---
https://ansm.sante.fr/actualites/chlorhexidine-attention-au-risque-de-reaction-allergique-immediate-grave
2023
false
false
false
France
French
chlorhexidine
anti-infective agents, local
hypersensitivity, immediate
drug hypersensitivity
pharmacovigilance note
---
https://www.has-sante.fr/jcms/p_3339982/fr/chlorhexidine-biogaran-digluconate-de-chlorhexidine-infections-buccales-et-soins-post-operatoires
2022
France
evaluation of the transparency committee
mouth, nos
nursing
chlorhexidine
Infectious disease
postoperative care
chlorhexidine gluconate
Infections
chlorhexidine
postoperative infection
---
https://www.has-sante.fr/jcms/p_3280984/fr/adontex-chlorhexidine
2021
false
false
false
France
insurance, health, reimbursement
treatment outcome
mouthwashes
pharmaceutical solutions
administration, topical
chlorhexidine
anti-infective agents, local
gingivitis
periodontitis
preoperative care
postoperative care
adult
child
dentistry
evaluation of the transparency committee
chlorhexidine gluconate
chlorhexidine
---
https://www.has-sante.fr/jcms/p_3262661/fr/chlorhexidine-digluconate-/-alcool-isopropylique-gilbert-healthcare-chlorhexidine-digluconate/alcool-isopropylique
2021
false
false
false
France
chlorhexidine, combinations
administration, cutaneous
drug combinations
anti-infective agents, local
dermatologic agents
preoperative care
Preoperative disinfection of skin (procedure)
pharmaceutical solutions
evaluation of the transparency committee
chlorhexidine gluconate
chlorhexidine
2-Propanol
---
https://www.has-sante.fr/jcms/pprd_2982841/fr/chlorhexidine-digluconate-de-chlorhexidine
2021
France
evaluation of the transparency committee
chlorhexidine gluconate
chlorhexidine
chlorhexidine
---
https://dumas.ccsd.cnrs.fr/dumas-02496201
France
dissertations, academic
endodontist
Memory
deposition, nos
endodontics
Systematic Review
Systematics
Clinical Study
Systematics
Academic Dissertation
Memory
Taxonomy
chlorhexidine
memory
Systematics
chlorhexidine
memory, nos
Systematic Review
Clinical Study
---
https://www.has-sante.fr/jcms/p_3199395/fr/adontex
2020
false
false
false
France
French
evaluation of the transparency committee
mouthwashes
insurance, health, reimbursement
adult
child
chlorhexidine gluconate
chlorhexidine
anti-infective agents, local
periodontal diseases
gingivitis
periodontitis
preoperative care
postoperative care
administration, topical
chlorhexidine
chlorhexidine
---
https://www.has-sante.fr/jcms/p_3168608/fr/chloraprep
2020
false
false
false
France
chlorhexidine gluconate
2-Propanol
chlorhexidine, combinations
evaluation of the transparency committee
chlorhexidine
---
https://www.cochrane.org/fr/CD012248/baigner-les-patients-gravement-malades-avec-de-la-chlorhexidine-pour-prevenir-les-infections
2019
false
false
false
France
United Kingdom
baths
anti-infective agents, local
review of literature
french abstract
bathing patient, nos
chlorhexidine
critical illness
cross infection
nosocomial infectious disease, nos
---
https://www.has-sante.fr/portail/jcms/c_2908496/fr/chlorhexidine-arrow
2019
false
true
false
false
France
chlorhexidine gluconate
mouthwashes
anti-infective agents, local
administration, oral
Oral infection (disorder)
adult
child
chlorhexidine
insurance, health, reimbursement
evaluation of the transparency committee
chlorhexidine
chlorhexidine
---
https://www.has-sante.fr/portail/jcms/c_2908484/fr/chlorhexidine-mylan
2019
false
true
false
false
France
chlorhexidine gluconate
chlorhexidine
mouthwashes
anti-infective agents, local
administration, oral
Oral infection (disorder)
child
adult
chlorhexidine
insurance, health, reimbursement
evaluation of the transparency committee
chlorhexidine
chlorhexidine
---
https://www.has-sante.fr/portail/jcms/c_2908450/fr/chlorhexidine-biogaran
2019
false
true
false
false
France
chlorhexidine gluconate
chlorhexidine
mouthwashes
anti-infective agents, local
administration, oral
Oral infection (disorder)
adult
child
chlorhexidine
insurance, health, reimbursement
evaluation of the transparency committee
chlorhexidine
chlorhexidine
---
https://www.has-sante.fr/portail/jcms/c_2899211/fr/chloraprep-colore-chloraprep
2019
false
false
false
France
insurance, health, reimbursement
treatment outcome
drug combinations
chlorhexidine gluconate
2-Propanol
administration, cutaneous
anti-infective agents, local
chlorhexidine, combinations
vascular catheters
antisepsis
evaluation of the transparency committee
vascular access devices
chlorhexidine
chlorhexidine
---
https://www.has-sante.fr/jcms/p_3111985/fr/plurexid
2019
false
false
false
France
chlorhexidine
insurance, health, reimbursement
evaluation of the transparency committee
---
https://www.canada.ca/fr/sante-canada/services/substances-chimiques/fiches-renseignements/en-bref/chlorhexidine-sels.html
2017
false
false
false
Canada
French
scientific and technical information
chlorhexidine
chlorhexidine
salts
---
http://www.has-sante.fr/portail/jcms/c_2617883/fr/paroex
http://www.has-sante.fr/portail/jcms/c_1036552/paroex
2016
false
France
French
postoperative care
oral surgical procedures
mouth diseases
chlorhexidine
chlorhexidine gluconate
anti-infective agents, local
insurance, health, reimbursement
administration, buccal
chlorhexidine
mouthwashes
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_2637984/fr/diaseptyl
http://www.has-sante.fr/portail/jcms/c_1036272/diaseptyl
2016
false
France
French
antisepsis
treatment outcome
administration, cutaneous
chlorhexidine gluconate
chlorhexidine
chlorhexidine
anti-infective agents, local
insurance, health, reimbursement
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_2658522/fr/prexidine
http://www.has-sante.fr/portail/jcms/c_928157/prexidine
2016
false
France
French
Oral infection (disorder)
oral surgical procedures
postoperative care
chlorhexidine gluconate
mouthwashes
chlorhexidine
chlorhexidine
anti-infective agents, local
adult
child
adolescent
treatment outcome
evaluation of the transparency committee
---
http://www.cochrane.org/fr/CD008457/traitement-antiseptique-chlorhexidine-pour-prevenir-la-carie-dentaire-chez-les-enfants-et-les-jeunes
2015
false
false
false
France
United Kingdom
French
review of literature
treatment outcome
french abstract
adolescent
dental caries
chlorhexidine
anti-infective agents, local
child
---
http://www.cochrane.org/fr/CD007835/soins-de-la-peau-a-la-chlorhexidine-pour-la-prevention-de-la-mortalite-et-des-infections-chez-les-nouveau-nes
2015
false
false
false
France
United Kingdom
French
french abstract
chlorhexidine
anti-infective agents, local
infant, newborn
treatment outcome
infant
skin care
umbilical cord
infection control
comparative study
infant mortality
review of literature
Infection in the neonate
---
http://www.has-sante.fr/portail/jcms/c_2585432/fr/dermobacter
http://www.has-sante.fr/portail/jcms/c_987228/dermobacter
http://www.has-sante.fr/portail/jcms/c_400907/fr/dermobacter
2015
false
France
French
benzalkonium chloride
drug combinations
administration, cutaneous
insurance, health, reimbursement
benzalkonium compounds
anti-infective agents, local
chlorhexidine gluconate
chlorhexidine
chlorhexidine, combinations
treatment outcome
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_2563006/fr/dosiseptine
http://www.has-sante.fr/portail/jcms/c_964931/dosiseptine
2015
false
France
French
antisepsis
chlorhexidine gluconate
chlorhexidine
anti-infective agents, local
administration, cutaneous
chlorhexidine
insurance, health, reimbursement
evaluation of the transparency committee
---
http://www.cochrane.org/fr/CD004070/chlorhexidine-vaginale-durant-le-travail-pour-la-prevention-des-infections-maternelles-et-neonatales-a-lexclusion-des-infections-a-streptocoques-du-groupe-b-et-du-vih
2014
false
false
false
France
United Kingdom
French
meta-analysis
french abstract
chlorhexidine
anti-infective agents, local
chorioamnionitis
vaginal douching
treatment outcome
---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=67960413
2014
false
false
false
France
French
summary of product characteristics
mouthwashes
solution, nos
chlorhexidine
chlorhexidine
chlorhexidine gluconate
solutions
solutions
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67691977
2014
false
false
false
France
French
summary of product characteristics
package leaflet
administration, cutaneous
chlorhexidine gluconate
benzalkonium compounds
chlorhexidine
solution, nos
solutions
benzalkonium chloride
skin, nos
benzalkonium chloride
chlorhexidine
solutions
---
http://www.has-sante.fr/portail/display.jsp?id=c_486309
http://www.has-sante.fr/portail/jcms/c_1188937/cyteal
http://www.has-sante.fr/portail/jcms/c_724427/cyteal
http://www.has-sante.fr/portail/jcms/c_1716244/fr/cyteal
http://www.has-sante.fr/portail/jcms/c_1716243/fr/cyteal18122013avisct13052
2013
France
French
skin diseases
superinfection
treatment outcome
chlorhexidine
chlorhexidine, combinations
pharmaceutical solutions
benzamidines
cresols
anti-infective agents, local
dermatologic agents
chlorocresol
hexamidine
chlorhexidine gluconate
drug combinations
administration, cutaneous
skin diseases, bacterial
evaluation of the transparency committee
hexamidine diisethionate
---
https://sf2h.net/publications/gestion-preoperatoire-risque-infectieux-mise-a-jour-de-conference-de-consensus
2013
true
false
France
French
infection control
consensus
surgical wound infection
skin care
anti-infective agents, local
bathing patient in shower
chlorhexidine
hair removal
antisepsis
detergents
surgical drapes
staphylococcus aureus
staphylococcal infections
carrier state
skin
nose
---
http://www.has-sante.fr/portail/jcms/c_1188967/biorgasept
http://www.has-sante.fr/portail/jcms/c_1543501/fr/biorgasept
http://www.has-sante.fr/portail/jcms/c_623576/biorgasept
2013
France
French
administration, cutaneous
treatment outcome
insurance, health, reimbursement
chlorhexidine
anti-infective agents, local
chlorhexidine
skin diseases, bacterial
chlorhexidine gluconate
evaluation of the transparency committee
antisepsis
wound infection
surgical wound infection
---
http://www.has-sante.fr/portail/jcms/c_1670193/fr/chloraprep
http://www.has-sante.fr/portail/jcms/c_1670192/fr/chloraprep-16102013-avis-ct13214
2013
France
French
administration, cutaneous
pharmaceutical solutions
chlorhexidine gluconate
2-Propanol
drug combinations
chlorhexidine
anti-infective agents, local
chlorhexidine, combinations
preoperative care
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_1189013/septeal
http://www.has-sante.fr/portail/jcms/c_724588/septeal
http://www.has-sante.fr/portail/jcms/c_1716247/fr/septeal
http://www.has-sante.fr/portail/jcms/c_1716246/fr/septeal18122013avisct13051
2013
France
French
chlorhexidine
chlorhexidine gluconate
antisepsis
skin diseases, bacterial
skin diseases
superinfection
treatment outcome
administration, cutaneous
chlorhexidine
anti-infective agents, local
insurance, health, reimbursement
evaluation of the transparency committee
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68318162
2012
France
summary of product characteristics
package leaflet
gilbert disease
alcohols
chlorhexidine
administration, cutaneous
coloring agents
alcoholism
staining and labeling
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61661906
2012
France
summary of product characteristics
package leaflet
chlorhexidine
alcoholism
gilbert disease
alcohols
administration, cutaneous
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61164092
2012
France
summary of product characteristics
package leaflet
chlorhexidine
administration, topical
gilbert disease
coloring agents
staining and labeling
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65108123
2012
France
summary of product characteristics
package leaflet
administration, topical
gilbert disease
chlorhexidine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69156980
2012
France
summary of product characteristics
package leaflet
chlorhexidine
mouthwashes
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66226772
2012
France
package leaflet
summary of product characteristics
chlorobutanol
chlorhexidine gluconate
mouthwashes
chlorhexidine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63169608
2012
France
summary of product characteristics
package leaflet
administration, cutaneous
alcohols
gluconates
chlorhexidine
chlorhexidine gluconate
alcoholism
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64178204
2012
France
summary of product characteristics
package leaflet
staining and labeling
alcohols
administration, cutaneous
gluconates
chlorhexidine
alcoholism
coloring agents
chlorhexidine gluconate
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61703999
2012
France
summary of product characteristics
package leaflet
chlorhexidine
gluconates
administration, topical
chlorhexidine gluconate
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68524397
2012
France
summary of product characteristics
package leaflet
administration, cutaneous
anti-infective agents, local
chlorhexidine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66245331
2012
France
summary of product characteristics
package leaflet
administration, cutaneous
chlorhexidine gluconate
gilbert disease
chlorhexidine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68574610
2012
France
summary of product characteristics
package leaflet
chlorhexidine
mouthwashes
chlorhexidine gluconate
chlorobutanol
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65450408
2012
France
summary of product characteristics
package leaflet
chlorhexidine
chlorobutanol
mouthwashes
chlorhexidine gluconate
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62330528
2012
France
summary of product characteristics
package leaflet
mouthwashes
chlorhexidine gluconate
chlorhexidine
chlorobutanol
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68783058
2012
France
summary of product characteristics
package leaflet
chlorobutanol
mouthwashes
chlorhexidine
chlorhexidine gluconate
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63231675
2012
France
summary of product characteristics
package leaflet
mouthwashes
chlorhexidine gluconate
chlorobutanol
chlorhexidine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62374058
2012
France
summary of product characteristics
package leaflet
chlorhexidine gluconate
chlorhexidine
coloring agents
gluconates
2-Propanol
administration, cutaneous
staining and labeling
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66820764
2012
France
summary of product characteristics
package leaflet
chlorhexidine gluconate
gels
chlorhexidine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64391565
2012
France
summary of product characteristics
package leaflet
administration, cutaneous
chlorhexidine
chlorhexidine gluconate
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62566852
2012
France
summary of product characteristics
package leaflet
benzalkonium chloride
benzalkonium compounds
chlorhexidine gluconate
administration, cutaneous
chlorhexidine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65555398
2012
France
summary of product characteristics
package leaflet
chlorobutanol
chlorhexidine
mouthwashes
chlorhexidine gluconate
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65602182
2012
France
summary of product characteristics
package leaflet
chlorobutanol
mouthwashes
chlorhexidine
chlorhexidine gluconate
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60529613
2012
France
summary of product characteristics
package leaflet
chlorhexidine
mouthwashes
chlorhexidine gluconate
chlorobutanol
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69906072
2012
France
summary of product characteristics
package leaflet
chlorhexidine
chlorhexidine gluconate
staining and labeling
coloring agents
administration, cutaneous
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60665912
2012
France
summary of product characteristics
package leaflet
sweetening agents
chlorhexidine
tetracaine
chlorhexidine gluconate
anise
tetrracaine hydrochloride
potassium
pimpinella
mentha
acetosulfame
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67546088
2012
France
summary of product characteristics
package leaflet
citrus paradisi
tetrracaine hydrochloride
chlorhexidine gluconate
chlorhexidine
grapefruit
tetracaine
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64503466
2012
France
summary of product characteristics
package leaflet
tetracaine
sweetening agents
chlorhexidine gluconate
chlorhexidine
elderberry
acetosulfame
tetrracaine hydrochloride
sambucus
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60963905
2012
France
summary of product characteristics
package leaflet
gluconates
chlorhexidine
chlorhexidine gluconate
---
http://www.cochrane.org/fr/CD006968
2012
France
United Kingdom
French
meta-analysis
french abstract
dry socket
dry socket
treatment outcome
chlorhexidine
mouthwashes
anti-infective agents, local
dental disinfectants
---
http://www.has-sante.fr/portail/jcms/c_1188980/baseal
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-01/baseal_14_12_2011_avis_ct_11105.pdf
http://www.has-sante.fr/portail/jcms/c_677495/baseal
2011
France
French
treatment outcome
chlorhexidine gluconate
chlorhexidine
anti-infective agents, local
dermatologic agents
administration, cutaneous
insurance, health, reimbursement
chlorhexidine
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_1036306/chloraprep-colore
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-03/chloraprepcolore_-_ct9127.pdf
2011
France
French
drug combinations
administration, cutaneous
chlorhexidine gluconate
chlorhexidine
2-Propanol
anti-infective agents, local
chlorhexidine, combinations
treatment outcome
preoperative care
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/jcms/c_928161/paroex
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-03/paroex_-_ct-6256.pdf
2010
France
French
treatment outcome
chlorhexidine gluconate
chlorhexidine
mouthwashes
chlorhexidine
anti-infective agents, local
evaluation of the transparency committee
---
https://www.inspq.qc.ca/sites/default/files/publications/870_aviscatheters.pdf
2008
Canada
French
analgesia, epidural
chlorhexidine
disinfectants
catheterization
guideline
---
http://www.has-sante.fr/portail/display.jsp?id=c_451758
2006
France
French
Adrenocortical steroid therapy
corticosteroid therapy
chlorhexidine
anti-infective agents
chlorhexidine
hydrocortisone
anti-infective agents, local
hydrocortisone
drug combinations
tixocortol pivalate
chlorhexidine gluconate
tixocortol
chlorhexidine
evaluation of the transparency committee
---
http://www.has-sante.fr/portail/display.jsp?id=c_400237
2005
France
French
anti-infective agents, local
chlorhexidine
solutions
chlorhexidine
dermatologic agents
chlorhexidine gluconate
chlorhexidine
evaluation of the transparency committee
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http://www.has-sante.fr/portail/display.jsp?id=c_399589
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct021144.pdf
2002
France
French
corticosteroid therapy
anti-infective agents, local
chlorhexidine
hydrocortisone
drug combinations
tixocortol pivalate
chlorhexidine
chlorhexidine gluconate
oral sprays
administration, buccal
evaluation of the transparency committee
---