Chlorhexidine - CISMeF

Preferred Label : Chlorhexidine;

NCIt definition : A biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged microbial cell surface, thereby destroying the integrity of the cell membrane. Subsequently, chlorhexidine penetrates into the cell and causes leakage of intracellular components leading to cell death. Since gram positive bacteria are more negatively charged, they are more sensitive to this agent.;

UNII : R4KO0DY52L;

InChIKey : GHXZTYHSJHQHIJ-UHFFFAOYSA-N;

CAS number : 55-56-1;

Chemical formula : C22H30Cl2N10;

ChEBI ID : CHEBI:3614;

Details

Origin ID

C364;

UMLS CUI

C0008196;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Chlorhexidine [ICD-11 Extension code]
- Chlorhexidine [LOINC component]
- Chlorhexidine (substance) [SNOMED CT concept]
- Product containing chlorhexidine (medicinal product) [SNOMED CT concept]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [Substance BNPC]
- chlorhexidine [MeSH concept]
- chlorhexidine [SNOMED Notion]
- chlorhexidine [MeSH Descriptor]
Validated automatic mappings to BTNT
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
- chlorhexidine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_salt_form
- Chlorhexidine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Chlorhexidine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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