chlorambucil - CISMeF

Preferred Label : chlorambucil;

MeSH definition : A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed);

MeSH synonym : n,n-di-(2-chloroethyl)-p-aminophenylbutyric acid; 4-(bis(2-chloroethyl)amino)benzenebutanoic acid; chlorbutin; chloraminophene;

CISMeF synonym : GlaxoSmithKline brand of chlorambucil; glaxo wellcome brand of chlorambucil; wellcome brand of chlorambucil;

MeSH hyponym : lympholysin; leukeran; CB-1348; NSC-3088; amboclorin; NSC 3088; NSC3088; CB 1348; CB1348;

MeSH CAS label : benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-;

MeSH Related Number : 305-03-3 (Chlorambucil);

Registry Number MeSH : 305-03-3;

Wikipedia link : https://en.wikipedia.org/wiki/Chlorambucil;

Codes EINECS : 206-162-0;

Is substance : O;

medicament (CISMeF) : O;

UNII : 18D0SL7309;

InChIKey : JCKYGMPEJWAADB-UHFFFAOYSA-N;

Details

Origin ID

D002699;

UMLS CUI

C0008163;

ATC code(s)
- chlorambucil [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Chlorambucil adverse reaction (disorder) [SNOMED CT concept]
- Poisoning caused by chlorambucil (disorder) [SNOMED CT concept]
- chlorambucil [Substance BNPC]
Currated CISMeF NLP mapping
- Chlorambucil [ICD-11 Extension code]
- Chlorambucil [ICHI extension code]
- Chlorambucil [SMS substance]
- Chlorambucil [NCIt concept]
- Chlorambucil (substance) [SNOMED CT concept]
- chlorambucil [SNOMED Notion]
Pharmacological action(s)
- antineoplastic agents, alkylating [MeSH Descriptor]
Record concept(s)
- CB-1348 [MeSH concept]
- NSC-3088 [MeSH concept]
- amboclorin [MeSH concept]
- chlorambucil [MeSH concept]
- leukeran [MeSH concept]
- lympholysin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,3-dipalmitoyl-2-(4-(bis(2-chloroethyl)amino)benzenebutanoyl)glycerol [MeSH Supplementary Concept]
- 17-hydroxy-3-aza-A-homo-4-androsten-4-one (4-(bis(2-chloroethyl)amino)phenyl)butyrate [MeSH Supplementary Concept]
- 17-hydroxy-4-aza-A-nor-5-androsten-3-one (4-N,N-bis(2-chloroethylamino)phenyl)butyrate [MeSH Supplementary Concept]
- 3,3-difluorochlorambucil [MeSH Supplementary Concept]
- 3,4-dehydrochlorambucil [MeSH Supplementary Concept]
- 3-hydroxy-13,17-seco-5-androsten-17-oic-13,17-lactam (4-(bis(2-chloroethyl)amino)phenyl)butyrate [MeSH Supplementary Concept]
- 3-hydroxy-13,17-secoandrostan-17-oic-13,17-lactam (4-(bis(2-chloroethyl)amino)phenyl)butyrate [MeSH Supplementary Concept]
- APC protocol [MeSH Supplementary Concept]
- CHIVPP protocol [MeSH Supplementary Concept]
- CHLOROPP protocol [MeSH Supplementary Concept]
- CMPP protocol [MeSH Supplementary Concept]
- COA protocol [MeSH Supplementary Concept]
- ChlVPP protocol [MeSH Supplementary Concept]
- ChlVPP-EVA regimen [MeSH Supplementary Concept]
- LBCMVD-56 protocol [MeSH Supplementary Concept]
- LMF protocol [MeSH Supplementary Concept]
- LMFP protocol [MeSH Supplementary Concept]
- LOPP protocol 1 [MeSH Supplementary Concept]
- MCP protocol [MeSH Supplementary Concept]
- MDC protocol [MeSH Supplementary Concept]
- MVLP protocol [MeSH Supplementary Concept]
- OPEC protocol 2 [MeSH Supplementary Concept]
- PEEC protocol [MeSH Supplementary Concept]
- PEEC-M protocol [MeSH Supplementary Concept]
- VAB-III protocol [MeSH Supplementary Concept]
- VAB-IV protocol [MeSH Supplementary Concept]
- VCCP protocol [MeSH Supplementary Concept]
- aminochlorambucil [MeSH Supplementary Concept]
- bestrabucil [MeSH Supplementary Concept]
- chlorambucil N-oxide [MeSH Supplementary Concept]
- chlorambucil half mustard [MeSH Supplementary Concept]
- chlorambucil-N-(2-(4-(4-bis(2-chloroethyl)aminophenyl)butyryl)aminoethyl)-5-(4-amidinophenyl)-2-furancarboxamide hydrochloride [MeSH Supplementary Concept]
- chlorambucil-arachidonic acid conjugate [MeSH Supplementary Concept]
- chlorambucil-docosahexaenoic acid conjugate [MeSH Supplementary Concept]
- chlorambucil-oleic acid conjugate [MeSH Supplementary Concept]
- chlorambucil-scopine [MeSH Supplementary Concept]
- chlorambucil-spermidine conjugate [MeSH Supplementary Concept]
- chlorambucil-taurocholate [MeSH Supplementary Concept]
- chlorambucil-tertiary butyl ester [MeSH Supplementary Concept]
- chlorambucyl-proline [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Chlorambucil [ICD-11 Extension code]
- Chlorambucil [NCIt concept]
- Chlorambucil (substance) [SNOMED CT concept]
- Product containing chlorambucil (medicinal product) [SNOMED CT concept]
- chlorambucil [ATC Code]
- chlorambucil [Substance BNPC]
- chlorambucil [SNOMED Notion]
Validated automatic mappings to BTNT
- chlorambucil [ATC Code]

Keyword's position in hierarchy(ies) :

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