Preferred Label : Chlorambucil;
NCIt synonyms : Lympholysin; Leukersan; gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid; Chlorobutin; chloroambucil; p-(N, N-di-2-chloroethyl)aminophenyl butyric acid; p-N, N-di-(beta-chloroethyl)aminophenyl butyric acid; Leukoran; butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl); 4-[bis(2-chloroethyl)amino]benzenebutanoic acid; Elcoril; aminochlorambucil; N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid; benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]- (9CI); Chlorobutine; Chlorambucilum; gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acid; CHL; chlorbutinum; Ecloril;
NCIt related terms : .gamma.-(p-bis(2-chloroethyl)aminophenyl)butyric acid; Chlorbutine; Linfolizin; p-N, N-Di-(.beta.-chloroethyl)aminophenyl butyric acid; Phenylbutyric acid nitrogen mustard; Ambochlorin; .gamma.-[p-bis(2-chloroethyl)aminophenyl]butyric acid; CB 1348; Butyric acid, 4-(p-[bis(2-chloroethyl)amino]phenyl)-; Chlorbutin; Linfolysin; Leukeran; Butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl)-; Amboclorin; .gamma.-[p-Di(2-chloroethyl)aminophenyl]butyric acid; Chloraminophen; N,N-Di-2-chloroethyl-.gamma.-p-aminophenylbutyric acid; Chloraminophene; 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid;
NCIt definition : An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates
and cross-links DNA during all phases of the cell cycle, resulting in disruption of
DNA function, cell cycle arrest, and apoptosis. (NCI04);
Alternative definition : NCI-GLOSS: A drug used to treat several types of leukemias and lymphomas. It blocks
cell growth by damaging the cell's DNA and may kill cancer cells. It is a type of
alkylating agent.;
UNII : 18D0SL7309;
InChIKey : JCKYGMPEJWAADB-UHFFFAOYSA-N;
CAS number : 305-03-3;
Drug name : Alti-chlorambucil; Leukeran; Chloraminophene;
Molecule name : WR-139013; CB-1348;
Chemical formula : C14H19Cl2NO2;
NSC code : 3088;
ChEBI ID : CHEBI:28830;
Codes from synonyms : NSC0260461; CDR0000662514; CDR0000046048; NSC0003088; 100;
Origin ID : C362;
UMLS CUI : C0008163;
False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
