captopril - CISMeF

Preferred Label : captopril;

MeSH definition : A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.;

MeSH synonym : (s)-1-(3-mercapto-2-methyl-1-oxopropyl)-l-proline;

MeSH hyponym : sq-14225; lopirin; SQ-14,225; capoten; SQ 14,225; SQ14,225; SQ 14225; SQ14225;

Related MeSH term : sq-14534; SQ-14,534; SQ 14,534; SQ14,534; SQ 14534; SQ14534;

MeSH CAS label : L-Proline, 1-(3-mercapto-2-methyl-1-oxopropyl)-, (S)-;

MeSH Related Number : 62571-86-2 (Captopril); 63250-36-2 ((R)-isomer);

Registry Number MeSH : 62571-86-2;

Wikipedia link : https://en.wikipedia.org/wiki/Captopril;

Codes EINECS : 263-607-1;

Is substance : O;

UNII : 9G64RSX1XD;

InChIKey : FAKRSMQSSFJEIM-RQJHMYQMSA-N;

Details

Origin ID

D002216;

UMLS CUI

C0006938;

ATC code(s)
- captopril [ATC Code]
- captopril and diuretics [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Captopril adverse reaction (disorder) [SNOMED CT concept]
- Captopril measurement (procedure) [SNOMED CT concept]
- captopril [Substance BNPC]
Currated CISMeF NLP mapping
- Captopril [ICD-11 Extension code]
- Captopril [LOINC component]
- Captopril [ICHI extension code]
- Captopril [SMS substance]
- Captopril [NCIt concept]
- Captopril (substance) [SNOMED CT concept]
- captopril [SNOMED Notion]
Fils d'après SNOMED CT
- angiotensin-converting enzyme inhibitors [MeSH Descriptor]
Pharmacological action(s)
- angiotensin-converting enzyme inhibitors [MeSH Descriptor]
- antihypertensive agents [MeSH Descriptor]
Record concept(s)
- SQ-14,225 [MeSH concept]
- SQ-14,534 [MeSH concept]
- capoten [MeSH concept]
- captopril [MeSH concept]
- lopirin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4-fluorocaptopril [MeSH Supplementary Concept]
- S-benzoyl captopril [MeSH Supplementary Concept]
- S-benzylcaptopril [MeSH Supplementary Concept]
- S-methylcaptopril [MeSH Supplementary Concept]
- S-nitrosocaptopril [MeSH Supplementary Concept]
- SQ 26703 [MeSH Supplementary Concept]
- alacepril [MeSH Supplementary Concept]
- captopril N-ethylmaleimide sulfone [MeSH Supplementary Concept]
- captopril N-ethylmaleimide sulfoxide [MeSH Supplementary Concept]
- captopril disulfide [MeSH Supplementary Concept]
- captopril ethyl ester [MeSH Supplementary Concept]
- captopril, hydrochlorothiazide drug combination [MeSH Supplementary Concept]
- captopril-cysteine [MeSH Supplementary Concept]
- desacetyl-alacepril [MeSH Supplementary Concept]
- silacaptopril [MeSH Supplementary Concept]
- zofenopril [MeSH Supplementary Concept]
- zofenoprilate [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Captopril [ICD-11 Extension code]
- Captopril [LOINC Challenge]
- Captopril [NCIt concept]
- Captopril [LOINC component]
- Captopril (substance) [SNOMED CT concept]
- Product containing captopril (medicinal product) [SNOMED CT concept]
- captopril [ATC Code]
- captopril [Substance BNPC]
- captopril [SNOMED Notion]
Validated automatic mappings to BTNT
- captopril [ATC Code]

Keyword's position in hierarchy(ies) :

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