Preferred Label : auranofin;
MeSH definition : An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact
mechanism of action is unknown, but it is believed to act via immunological mechanisms
and alteration of lysosomal enzyme activity. Its efficacy is slightly less than that
of injected gold salts, but it is better tolerated, and side effects which occur are
potentially less serious.;
CISMeF synonym : SmithKline beecham brand of auranofin; auranofin recordati brand; auranofin robapharm brand; auranofin rubio brand; auranofin yamanouchi brand; recordati brand of auranofin; robapharm brand of auranofin; rubio brand of auranofin; yamanouchi brand of auranofin;
MeSH hyponym : SK&F D 39162; crisinor; ridauran; ridaura; SK&F-39162; SK&F 39162; SK&F39162;
MeSH CAS label : gold, (1-thio-beta-D-glucopyranose 2,3,4,6-tetraacetato-S)(triethylphosphine)-;
MeSH Related Number : 34031-32-8 (Auranofin);
Registry Number MeSH : 34031-32-8;
Codes EINECS : 251-801-9;
Is substance : O;
UNII : 3H04W2810V;
InChIKey : AUJRCFUBUPVWSZ-XTZHGVARSA-M;
Origin ID : D001310;
UMLS CUI : C0004320;
ATC code(s)
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CISMeF manual mappings
Currated CISMeF NLP mapping
Pharmacological action(s)
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An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact
mechanism of action is unknown, but it is believed to act via immunological mechanisms
and alteration of lysosomal enzyme activity. Its efficacy is slightly less than that
of injected gold salts, but it is better tolerated, and side effects which occur are
potentially less serious.
http://www.cochrane.org/fr/CD002048
2009
false
true
false
United Kingdom
France
auranofin
auranofin
treatment outcome
meta-analysis
french abstract
arthritis, rheumatoid
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