alpha-2-Antiplasmin

Preferred Label : alpha-2-Antiplasmin;

MeSH definition : A member of the serpin superfamily found in plasma that inhibits the lysis of fibrin clots which are induced by plasminogen activator. It is a glycoprotein, molecular weight approximately 70,000 that migrates in the alpha 2 region in immunoelectrophoresis. It is the principal plasmin inactivator in blood, rapidly forming a very stable complex with plasmin.;

MeSH synonym : alpha(2)-plasmin inhibitor; alpha 2 plasmin inhibitor; alpha 2-plasmin inhibitor; Serpin F2; alpha 2 antiplasmin; alpha-2 antiplasmin;

CISMeF synonym : plasmin antiactivator; inhibitor, alpha 2-plasmin; antiactivator, plasmin; antiplasmin, alpha-2;

Is substance : O;

Details

Origin ID

D000979;

UMLS CUI

C0003410;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- alpha-2-antiplasmin [Blood Transfusion thesaurus concept]
- antiplasmin [Blood Transfusion thesaurus concept]
Indexing information
- phlorofucofuroeckol A [MeSH Supplementary Concept]
Pharmacological action(s)
- antifibrinolytic agents [MeSH Descriptor]
- serine proteinase inhibitors [MeSH Descriptor]
Record concept(s)
- alpha-2-Antiplasmin [MeSH concept]
Related MeSH Supplementary Concept(s)
- SERPINF2 protein, human [MeSH Supplementary Concept]
- acetyl-glycyl-asparagyl-glutaminyl-glutamyl-glutaminyl-valyl-seryl-prolyl-leucyl-threonyl-leucyl-leucyl-lysyl-lysyl-tryptophyl-cysteinyl-Alexa fluoro 680 C2C2-maleimide conjugate [MeSH Supplementary Concept]
- alpha(2)-antiplasmin enschede [MeSH Supplementary Concept]
- anti-plasmin deficiency, congenital [MeSH Supplementary Concept]
- plasmin Paris-Trousseau [MeSH Supplementary Concept]
- plasmin-plasmin inhibitor complex [MeSH Supplementary Concept]
- pro-alpha-2-plasmin inhibitor [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Antiplasmin (substance) [SNOMED CT concept]
- alpha-2 plasmin inhibitor [SNOMED Notion]
- antiplasmin [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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