eflornithine - CISMeF

Preferred Label : eflornithine;

MeSH definition : An inhibitor of ornithine decarboxylase, the rate limiting enzyme of the polyamine biosynthetic pathway.;

MeSH synonym : alpha difluoromethylornithine; alpha-difluoromethyl ornithine; ornithine, alpha-difluoromethyl; alpha difluoromethyl ornithine; alpha-difluoromethylornithine; DL-alpha-Difluoromethylornithine; DL alpha difluoromethylornithine; Difluoromethylornithine;

CISMeF synonym : 96020-91-6 (Eflornithine hydrochloride); 71782, RMI; women first brand of eflornithine hydrochloride; eflornithine monohydrochloride, monohydrate; hydrochloride, eflornithine; monohydrochloride, monohydrate eflornithine;

MeSH hyponym : ornidyl; vaniqa; RMI 71782; eflornithine hydrochloride; MDL-71,782 A; MDL 71,782 A; MDL71,782 A;

Related MeSH term : difluoromethylornithine;

MeSH CAS label : ornithine, 2-(difluoromethyl)-;

MeSH Related Number : difluoromethylornithine; eflornithine hydrochloride; 67037-37-0 (Difluoromethylornithine); 70052-12-9 (Eflornithine); 96020-91-6 (mono-HCl, monohydrate); 4NH22NDW9H;

Registry Number MeSH : 70052-12-9;

Related CAS MeSH : 4NH22NDW9H (Eflornithine hydrochloride); ZQN1G5V6SR (Difluoromethylornithine);

MeSH annotation : DF:DFMO;

Wikipedia link : https://en.wikipedia.org/wiki/Eflornithine;

Is substance : O;

UNII : ZQN1G5V6SR;

InChIKey : VLCYCQAOQCDTCN-UHFFFAOYSA-N;

Details

Origin ID

D000518;

UMLS CUI

C0002260;

ATC code(s)
- eflornithine [ATC Code]
- eflornithine [ATC Code]
ATC code(s)
- eflornithine [ATC Code]
- eflornithine [ATC Code]
- eflornithine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Eflornithine [ICD-11 Extension code]
- Eflornithine [ICHI extension code]
- Eflornithine [NCIt concept]
- Eflornithine (substance) [SNOMED CT concept]
Pharmacological action(s)
- Ornithine Decarboxylase Inhibitors [MeSH Descriptor]
- antineoplastic agents [MeSH Descriptor]
- trypanocidal agents [MeSH Descriptor]
Record concept(s)
- Eflornithine Monohydrochloride, Monohydrate [MeSH concept]
- MDL-71,782 A [MeSH concept]
- RMI 71782 [MeSH concept]
- eflornithine [MeSH concept]
- eflornithine hydrochloride [MeSH concept]
- ornidyl [MeSH concept]
- vaniqa [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2-(fluoromethyl)dehydroornithine ethyl ester [MeSH Supplementary Concept]
- 2-(fluoromethyl)dehydroornithine methyl ester [MeSH Supplementary Concept]
- 2-fluoromethylornithine [MeSH Supplementary Concept]
- DFMO-PCV protocol [MeSH Supplementary Concept]
- alpha-(fluoromethyl)dehydroornithine [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Eflornithine [ICD-11 Extension code]
- Eflornithine [NCIt concept]
- Eflornithine (substance) [SNOMED CT concept]
- Product containing eflornithine (medicinal product) [SNOMED CT concept]
- eflornithine [ATC Code]
- eflornithine [ATC Code]

Keyword's position in hierarchy(ies) :

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