alpha 1-Antichymotrypsin

Preferred Label : alpha 1-Antichymotrypsin;

MeSH definition : Glycoprotein found in alpha(1)-globulin region in human serum. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. It is a member of the serpin superfamily.;

MeSH synonym : Serpin A3; alpha 1 antichymotrypsin; alpha(1)-Antichymotrypsin;

CISMeF synonym : 1-antichymotrypsin, alpha; glycoprotein gp68;

Is substance : O;

Details

Origin ID

D000514;

UMLS CUI

C0002190;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Alpha-1-Antichymotrypsin [NCIt concept]
- Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ORDO Gene]
- alpha1 antichymotrypsin [SNOMED Notion]
Currated CISMeF NLP mapping
- Alpha-1-Antichymotrypsin [LOINC component]
- Alpha-1-antichymotrypsin (substance) [SNOMED CT concept]
Pharmacological action(s)
- serine proteinase inhibitors [MeSH Descriptor]
Record concept(s)
- alpha 1-Antichymotrypsin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Alpha-1-Antichymotrypsin [LOINC component]
- Alpha-1-antichymotrypsin (substance) [SNOMED CT concept]
- alpha1 antichymotrypsin [SNOMED Notion]

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