Preferred Label : acetylcysteine;

MeSH definition : The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.;

MeSH synonym : n-acetylcysteine; n acetylcysteine; mercapturic acid; n-acetyl-l-cysteine; acid, mercapturic; n acetyl l cysteine;

CISMeF synonym : atid, acetylcystein; gnr, acétylcystéine; al, acetylcystein; chiron brand of acetylcysteine sodium salt; al, nac; heumann, acetylcystein; nac, larylin; roxane brand of acetylcysteine sodium salt; trom, acetylcystein; 19542-74-6 (Acetylcysteine, monosodium salt); 63664-54-0 (Acetylcysteine sodium); Bristol-Myers squibb brand of acetylcysteine; Bristol-Myers squibb brand of acetylcysteine sodium salt; GNR pharma brand of acetylcysteine; GNR-Pharma brand of acetylcysteine; UPSA brand of acetylcysteine; ac pharma brand of acetylcysteine; ac-Pharma brand of acetylcysteine; acetylcysteine GNR-Pharma brand; acetylcysteine UPSA brand; acetylcysteine ac-Pharma brand; acetylcysteine alcon brand; acetylcysteine aluid brand; acetylcysteine atid brand; acetylcysteine azupharma brand; acetylcysteine betapharm brand; acetylcysteine bioiberica brand; acetylcysteine bouchara brand; acetylcysteine centrafarm brand; acetylcysteine disphar brand; acetylcysteine farmasan brand; acetylcysteine fresenius brand; acetylcysteine guerbet brand; acetylcysteine génévrier brand; acetylcysteine hermes brand; acetylcysteine heumann brand; acetylcysteine inpharzam brand; acetylcysteine intra brand; acetylcysteine klinge brand; acetylcysteine krewel brand; acetylcysteine lichtenstein brand; acetylcysteine lindopharm brand; acetylcysteine merck brand; acetylcysteine oberlin brand; acetylcysteine pfleger brand; acetylcysteine pharbita brand; acetylcysteine roberts brand; acetylcysteine temmler brand; acetylcysteine teva brand; acetylcysteine thiemann brand; acetylcysteine trommsdorff brand; acetylcysteine whitehall brand; acetylcysteine zambon brand; acetylcysteine zyma brand; alcon brand of acetylcysteine; allen & hanburys brand of acetylcysteine; aluid brand of acetylcysteine; atid brand of acetylcysteine; azupharma brand of acetylcysteine; betapharm brand of acetylcysteine; bioiberica brand of acetylcysteine; boehringer ingelheim brand of acetylcysteine; bouchara brand of acetylcysteine; bristol myers squibb brand of acetylcysteine; bristol myers squibb brand of acetylcysteine sodium salt; centrafarm brand of acetylcysteine; dey brand of acetylcysteine sodium salt; disphar brand of acetylcysteine; farmasan brand of acetylcysteine; fresenius brand of acetylcysteine; guerbet brand of acetylcysteine; génévrier brand of acetylcysteine; hermes brand of acetylcysteine; heumann brand of acetylcysteine; inpharzam brand of acetylcysteine; intra brand of acetylcysteine; klinge brand of acetylcysteine; krewel brand of acetylcysteine; lichtenstein brand of acetylcysteine; lindopharm brand of acetylcysteine; merck brand of acetylcysteine; oberlin brand of acetylcysteine; pfleger brand of acetylcysteine; pharbita brand of acetylcysteine; produpharm lappe brand of acetylcysteine; roberts brand of acetylcysteine; roche nicholas brand of acetylcysteine; temmler brand of acetylcysteine; teva brand of acetylcysteine; thiemann brand of acetylcysteine; trommsdorff brand of acetylcysteine; whitehall brand of acetylcysteine; zambon brand of acetylcysteine; zyma brand of acetylcysteine;

DeCS synonym : Ac tylcyst ine GNR; Optipect Hustengetr nk;

MeSH hyponym : bisolvon NAC; exomuc; acetylcysteine, (DL)-Isomer; siccoral; acemuc; fabrol; fluprowit; acetylcystein heumann; muciteran; M-Pectil; acetylcysteine zinc; alveolex; acetylcystein atid; codotussyl; fluimucil; Broncho-Fips; acetylcysteine, (D)-Isomer; mentopin acetylcystein; jenacystein; hoestil; mucosil; acetylcysteine hydrochloride; lantamed; acebraus; durabronchal; airbron; acétylcystéine GNR; mucomyst; acetyst; broncoclar; frekatuss; dampo mucopect; eurespiran; broncholysin; azubronchin; acetylcysteine, monoammonium salt; lindocetyl; acetylcystein AL; acetylcysteine sodium; acetylcystein trom; ilube; cystamucil; mucosolvin; acetabs; solmucol; Genac; NAC AL; Hydrochloride, Acetylcysteine; Sodium, Acetylcysteine; Acetylcysteine, Monosodium Salt; Monosodium Salt Acetylcysteine; Zinc, Acetylcysteine; Monoammonium Salt Acetylcysteine; Bromuc; NAC, Bisolvon; Broncho Fips; BronchoFips; Mucopect, Dampo; Larylin NAC; NAC Zambon; Zambon, NAC; Optipect Hustengetränk; Hustengetränk, Optipect; Muco Sanigen; Sanigen, Muco; Jenapharm; M Pectil; MPectil; Acetylcystein, mentopin; Acetylin; Mucosol; Siran;

MeSH CAS label : L-Cysteine, N-acetyl-;

MeSH Related Number : acetylcysteine hydrochloride; acetylcysteine sodium; acetylcysteine zinc; acetylcysteine, (D)-Isomer; acetylcysteine, (DL)-Isomer; acetylcysteine, monoammonium salt; 128645-11-4 (Zn salt); 18829-79-3 (HCl); 26117-28-2 ((D)-isomer); 50807-78-8 (mono-NH3 salt); 616-91-1 (Acetylcysteine); 63664-54-0 (Na salt); 7218-04-4 ((DL)-isomer); NRD80R06FB;

Registry Number MeSH : 616-91-1;

Related CAS MeSH : 18829-79-3 (Acetylcysteine hydrochloride); 128645-11-4 (Acetylcysteine zinc); 26117-28-2 (Acetylcysteine, (D)-Isomer); 7218-04-4 (Acetylcysteine, (DL)-Isomer); 50807-78-8 (Acetylcysteine, monoammonium salt); NRD80R06FB (Acetylcysteine sodium);

Wikipedia link : https://en.wikipedia.org/wiki/Acetylcysteine;

Codes EINECS : 210-498-3;

Is substance : O;

UNII : WYQ7N0BPYC;

InChIKey : PWKSKIMOESPYIA-BYPYZUCNSA-N;

Details


Main resources

You can consult :

The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.

https://www.centreantipoisons.be/professionnels-de-la-sant/articles-pour-professionnels-de-la-sant/intoxications-aigu-s-et-antidot-13
2020
false
false
false
Belgium
poisoning
acetylcysteine
popular works
acetaminophen

---
https://www.has-sante.fr/portail/jcms/c_2973604/fr/mucomystendo
2019
true
false
France
French
acetylcysteine
acetylcysteine
instillation, drug
airway obstruction
expectorants
insurance, health, reimbursement
tracheotomy
evaluation of the transparency committee

---
https://www.cochrane.org/fr/CD012357/n-acetylcysteine-administree-avec-des-antibiotiques-pour-le-traitement-de-linfection-helicobacter
2019
false
true
false
false
France
United Kingdom
review of literature
french abstract
Antibiotics
antibiotics
acetylcysteine
infectious disease, nos
helicobacter pylori
administration of antibiotic
antibiotic therapy
anti-bacterial agents
helicobacter infections
acetylcysteine
helicobacter pylori

---
https://medicalforum.ch/fr/detail/doi/fms.2019.08364
https://doi.org/10.4414/fms.2019.08364
2019
false
false
false
Switzerland
acetaminophen
acetylcysteine
antidotes
drug overdose
acetylcysteine
Anaphylactoid reaction (disorder)
Poisoning caused by paracetamol (disorder)
Poisoning caused by acetylcysteine (disorder)
journal article

---
http://www.has-sante.fr/portail/jcms/c_2611683/fr/genac
http://www.has-sante.fr/portail/jcms/c_1074086/genac
http://www.has-sante.fr/portail/jcms/c_455427/genac
2016
false
France
French
evaluation of the transparency committee
treatment outcome
ophthalmic solutions
acetylcysteine
corneal ulcer
eye injuries
insurance, health, reimbursement
acetylcysteine
administration, ophthalmic

---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=62655991
2016
false
true
false
France
French
summary of product characteristics
package leaflet
administration, oral
expectorants
acetylcysteine
bronchitis
bronchial secretion disorders
acetylcysteine
acute disease

---
http://www.cnerea.fr/UserFiles/File/national/desc-des/livre-masson-2015/intox/antidotes.pdf
2015
true
false
false
France
French
educational course
French pre-residency program examination
poisoning
antidotes
antidotes
antidotes
charcoal
toxicology
acetylcysteine
flumazenil
naloxone
antidotes

---
http://www.pharmactuel.com/index.php/pharmactuel/article/view/1052
2014
false
false
false
Canada
French
journal article
acetylcysteine
Chemical and Drug Induced Liver Injury
antitubercular agents
isoniazid
free radical scavengers
acetylcysteine
pyrazinamide
acetylhydrazine
rifampin
Chemical and Drug Induced Liver Injury
signs and symptoms
alanine transaminase
liver failure, acute
antibiotic therapy
hydrazines

---
http://www.pharmactuel.com/index.php/pharmactuel/article/view/1048
2014
false
false
false
Canada
French
journal article
acetylcysteine

---
http://www.centreantipoisons.be/node/575
2014
false
true
false
Belgium
scientific and technical information
acetaminophen
acetaminophen
acetaminophen
acetaminophen
acetaminophen
acetylcysteine
acetylcysteine
acetylcysteine
acetylcysteine

---
http://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq.do?atid=n-acetyl-l-cysteine&lang=fra
2014
monograph pharmacy
acetylcysteine

---
http://www.lecrat.eu/?s=Ac%C3%A9tylcyst%C3%A9ine
France
drug information
acetylcysteine
pregnancy, nos
pregnancy, high-risk
teratogens

---
http://www.cochrane.org/fr/CD003124
2013
United Kingdom
France
French
meta-analysis
treatment outcome
child
acetylcysteine
carbocysteine
respiratory tract infections
acute disease
expectorants
french abstract

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69220963
2012
France
summary of product characteristics
package leaflet
acetylcysteine
expectorants
powders
sputum

---
http://www.has-sante.fr/portail/jcms/c_1230744/rhinofluimicil-04012012-synthese-ct8711
http://www.has-sante.fr/portail/jcms/c_1194227/rhinofluimucil-04012012-avis-ct8711
http://www.has-sante.fr/portail/jcms/c_1230780/rhinofluimucil-association-fixe-de-n-acetylcysteine-tuaminoheptane
2012
France
French
guidelines for drug use
evaluation of the transparency committee
amines
rhinofluimucil
tuaminoheptane
anti-infective agents, local
benzalkonium compounds
benzalkonium chloride
acetylcysteine
adult
child
nasal decongestants
common cold
tuaminoheptane
sympathomimetics
treatment outcome
randomized controlled trials as topic
administration, intranasal
nasal sprays
drug combinations
insurance, health, reimbursement

---
http://www.has-sante.fr/portail/display.jsp?id=c_490320
http://www.has-sante.fr/portail/jcms/c_1194008/rhinofluimucil
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-01/rhinofluimucil_04012012_avis__ct8711.pdf
2012
France
French
evaluation of the transparency committee
amines
adult
child
anti-infective agents, local
rhinofluimucil
drug combinations
administration, intranasal
nasal sprays
nasal decongestants
tuaminoheptane
benzalkonium compounds
benzalkonium chloride
acetylcysteine
tuaminoheptane
insurance, health, reimbursement
common cold
treatment outcome

---
http://www.cochrane.org/fr/CD006616
http://www.cochrane.org/fr/CD006616/comparaison-de-la-n-acetylcysteine-par-voie-intraveineuse-et-du-placebo-pour-le-traitement-du-syndrome-de-reponse-inflammatoire-systemique-et-de-la-septicemie-chez-ladulte-en-etat-grave
2012
false
true
false
United Kingdom
France
systemic inflammatory response syndrome
administration, intravenous
acetylcysteine
free radical scavengers
treatment outcome
meta-analysis
french abstract
sepsis
adult

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69896678
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69148542
2012
France
summary of product characteristics
package leaflet
acetylcysteine
tablets

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67494823
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61004262
2012
France
summary of product characteristics
package leaflet
expectorants
powders
acetylcysteine
pharmaceutical solutions
sputum

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61959564
2012
France
summary of product characteristics
package leaflet
tablets
sputum
expectorants
acetylcysteine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67423954
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66886216
2012
France
summary of product characteristics
package leaflet
acetylcysteine
tablets

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63976701
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65483582
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61362245
2012
France
summary of product characteristics
package leaflet
tablets
acetylcysteine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68043798
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62784356
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66398010
2012
France
summary of product characteristics
package leaflet
tablets
acetylcysteine

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68096854
2012
France
summary of product characteristics
package leaflet
acetylcysteine
powders
france

---
https://www.inspq.qc.ca/toxicologie-clinique/protocole-de-traitement-de-l-intoxication-l-acetaminophene
2011
false
true
false
Canada
acetylcysteine
charcoal
acetylcysteine
acetylcysteine
journal article
acetaminophen

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-10/genac_-_ct-11175.pdf
http://www.has-sante.fr/portail/jcms/c_1104018/genac
2011
France
French
evaluation of the transparency committee
acetylcysteine
ophthalmic solutions
acetylcysteine
corneal ulcer
insurance, health, reimbursement
treatment outcome
administration, ophthalmic

---
http://www.has-sante.fr/portail/jcms/c_1009513/euronac
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-12/euronac_-_ct8312.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_455401
2010
France
French
acetylcysteine
ophthalmic solutions
insurance, health, reimbursement
corneal ulcer
eye injuries
acetylcysteine
treatment outcome
administration, ophthalmic
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-12/mucomystendo_-_ct-9290.pdf
http://www.has-sante.fr/portail/jcms/c_1009510/mucomystendo
2010
France
French
acetylcysteine
acetylcysteine
instillation, drug
airway obstruction
expectorants
insurance, health, reimbursement
tracheotomy
evaluation of the transparency committee

---
http://www.aboutkidshealth.ca/Fr/HealthAZ/Drugs/Pages/Acetylcysteine.aspx
2008
Canada
popular works
drug information
child
acetylcysteine

---
https://www.minerva-ebp.be/fr/article/712
2006
false
false
minerva-ebm.be
Belgium
French
pulmonary disease, chronic obstructive
acetylcysteine
treatment outcome
antioxidants
oxidative stress
adult
aged
critical appraisal or critical reading

---
http://www.has-sante.fr/portail/display.jsp?id=c_400801
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct032379.pdf
2006
France
French
administration, oral
acetylcysteine
insurance, health, reimbursement
adult
child
adolescent
expectorants
treatment outcome
acetylcysteine
bronchitis
bronchopneumonia
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/display.jsp?id=c_400522
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct032099.pdf
2005
France
French
acetylcysteine
treatment outcome
adult
child
acetylcysteine
administration, oral
N,S-diacetylcysteine methyl ester
expectorants
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/display.jsp?id=c_400352
2005
France
evaluation of the transparency committee
powders
acetylcysteine
tablets

---
http://www.has-sante.fr/portail/display.jsp?id=c_400353
2005
France
evaluation of the transparency committee
acetylcysteine

---
http://www.has-sante.fr/portail/display.jsp?id=c_400354
2005
France
evaluation of the transparency committee
tablets
acetylcysteine

---
http://www.has-sante.fr/portail/display.jsp?id=c_400355
2005
France
evaluation of the transparency committee
tablets
acetylcysteine

---
http://www.has-sante.fr/portail/display.jsp?id=c_400356
2005
France
evaluation of the transparency committee
acetylcysteine
nomenclature
aged
powders

---
http://www.has-sante.fr/portail/display.jsp?id=c_400357
2005
France
evaluation of the transparency committee
acetylcysteine

---
http://www.has-sante.fr/portail/display.jsp?id=c_400608
2005
France
evaluation of the transparency committee
acetylcysteine
powders

---
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct032096.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_400519
2005
France
French
administration, oral
acetylcysteine
expectorants
treatment outcome
acetylcysteine
infant
child
adult
evaluation of the transparency committee

---
http://www.has-sante.fr/portail/display.jsp?id=c_399356
2002
France
evaluation of the transparency committee
tablets
acetylcysteine

---
http://www.has-sante.fr/portail/display.jsp?id=c_398805
2001
France
evaluation of the transparency committee
powders
acetylcysteine

---
http://www.has-sante.fr/portail/display.jsp?id=c_398807
2001
France
evaluation of the transparency committee
acetylcysteine
powders

---
http://www.has-sante.fr/portail/display.jsp?id=c_398806
2001
France
evaluation of the transparency committee
acetylcysteine
tablets

---
http://www.has-sante.fr/portail/display.jsp?id=c_398808
2001
France
evaluation of the transparency committee
tablets
acetylcysteine

---
http://www.has-sante.fr/portail/display.jsp?id=c_398804
2001
France
evaluation of the transparency committee
acetylcysteine
powders

---
http://www.has-sante.fr/portail/display.jsp?id=c_398803
2001
France
evaluation of the transparency committee
acetylcysteine
tablets

---
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