Tolvaptan - CISMeF

Preferred Label : Tolvaptan;

MeSH definition : A benzazepine derivative and selective VASOPRESSIN V2 RECEPTOR antagonist that is used to treat euvolemic and hypervolemic HYPONATREMIA. It is also used in the treatment of rapidly progressing AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE to slow the rate of cyst development and renal insufficiency.;

MeSH synonym : 7-Chloro-5-hydroxy-1-(2-methyl-4-(2-methylbenzoylamino)benzoyl)2,3,4,5-tetrahydro-1H-1-benzazepine;

MeSH hyponym : OPC-41061; OPC41061;

MeSH CAS label : Benzamide, N-(4-((7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl)-3-methylphenyl)-2-methyl-;

MeSH Related Number : 150683-30-0 (Tolvaptan);

Wikipedia link : https://en.wikipedia.org/wiki/Tolvaptan;

UNII : 21G72T1950;

Details

Origin ID

D000077602;

UMLS CUI

C1176308;

ATC code(s)
- tolvaptan [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Tolvaptan [NCIt concept]
- Tolvaptan [ICD-11 Extension code]
- Tolvaptan [SMS substance]
- Tolvaptan (substance) [SNOMED CT concept]
- tolvaptan [Substance BNPC]
MeSH indexing information
- hyponatremia [MeSH Descriptor]
- receptors, vasopressin [MeSH Descriptor]
Pharmacological action(s)
- Antidiuretic Hormone Receptor Antagonists [MeSH Descriptor]
Record concept(s)
- OPC 41061 [MeSH concept]
- samsca [MeSH concept]
- tolvaptan [MeSH concept]
See also inter- (CISMeF)
- Product containing tolvaptan (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- tolvaptan [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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