Preferred Label : Deferasirox;
MeSH definition : A triazole and benzoate derivative that acts as a selective iron chelator. It is used
in the management of chronic IRON OVERLOAD due to blood transfusion or non-transfusion
dependent THALASSEMIA.;
MeSH synonym : 4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid;
MeSH hyponym : ICL-670A; ICL-670; ICL670; ICL 670;
UNII : V8G4MOF2V9;
Origin ID : D000077588;
UMLS CUI : C1619629;
ATC code(s)
- Allowable qualifiers
- Currated CISMeF NLP mapping
- Pharmacological action(s)
- Record concept(s)
- Semantic type(s)
A triazole and benzoate derivative that acts as a selective iron chelator. It is used
in the management of chronic IRON OVERLOAD due to blood transfusion or non-transfusion
dependent THALASSEMIA.
https://ansm.sante.fr/tableau-marr/deferasirox
2023
false
false
false
France
French
administration, oral
risk management
medication errors
guidelines for drug use
patient education handout
continuity of patient care
Deferasirox
---
https://www.has-sante.fr/jcms/p_3392496/fr/deferasirox-teva-deferasirox-surcharge-en-fer-chronique
2022
false
false
false
France
evaluation of the transparency committee
Deferasirox
iron overload, nos
Iron overload
iron overload
---
https://www.ema.europa.eu/en/medicines/human/EPAR/deferasirox-accord
2020
false
false
false
United Kingdom
French
English
syndication feed
summary of product characteristics
package leaflet
drug evaluation
Deferasirox
drug approval
europe
treatment outcome
drugs, generic
iron chelating agents
iron chelating agents
chronic disease
iron overload
adult
child
administration, oral
blood transfusion
beta-Thalassemia
thalassemia
pregnancy
breast feeding
drug interactions
deferasirox
drug evaluation, preclinical
Deferasirox
---
https://www.ema.europa.eu/en/medicines/human/EPAR/deferasirox-mylan
2019
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
drugs, generic
Deferasirox
Deferasirox
iron chelating agents
iron chelating agents
iron overload
administration, oral
chronic disease
child
adult
aged
drug interactions
pregnancy
breast feeding
deferasirox
drug evaluation, preclinical
---
https://www.has-sante.fr/portail/jcms/c_2842737/fr/exjade
2018
false
false
false
false
France
French
evaluation of the transparency committee
exjade
triazoles
benzoates
Deferasirox
---
https://ansm.sante.fr/actualites/lansm-rappelle-la-necessite-de-disposer-dune-nouvelle-prescription-pour-obtenir-exjade-90-mg-ou-360-mg-comprimes-pellicules-seule-forme-disponible-a-compter-du-26-juillet-2018-point-dinformation
2018
false
false
false
false
France
French
drug prescriptions
administration, oral
guidelines for drug use
patient education handout
iron overload
iron chelating agents
iron chelating agents
beta-Thalassemia
blood transfusion
medication errors
deferasirox
triazoles
benzoates
triazoles
benzoates
Deferasirox
Deferasirox
---
http://www.has-sante.fr/portail/jcms/c_2745132/fr/exjade
2017
false
false
false
France
French
evaluation of the transparency committee
administration, oral
insurance, health, reimbursement
treatment outcome
iron chelating agents
deferasirox
iron overload
chronic disease
child
adolescent
thalassemia syndrome, nos
thalassemia
adult
blood transfusion
benzoates
triazoles
Deferasirox
---
http://www.cochrane.org/fr/CD007461/le-deferasirox-pour-la-correction-de-la-surcharge-en-fer-chez-les-personnes-atteintes-de-syndrome-myelodysplasique
2014
false
false
false
France
United Kingdom
French
review of literature
myelodysplastic syndromes
iron overload
iron chelating agents
treatment outcome
french abstract
Deferasirox
---
http://www.has-sante.fr/portail/jcms/c_1744046/fr/exjade
http://www.has-sante.fr/portail/display.jsp?id=c_455406
2014
false
false
false
France
French
evaluation of the transparency committee
administration, oral
insurance, health, reimbursement
treatment outcome
iron chelating agents
deferasirox
iron overload
chronic disease
orphan drug production
Deferasirox
---
http://www.has-sante.fr/portail/jcms/c_1753531/fr/exjade
2014
false
false
false
France
French
evaluation of the transparency committee
administration, oral
insurance, health, reimbursement
treatment outcome
iron chelating agents
deferasirox
iron overload
chronic disease
orphan drug production
child
adolescent
thalassemia syndrome, nos
thalassemia
Deferasirox
---
https://www.ema.europa.eu/medicines/human/EPAR/Exjade
2012
false
Non renseigné
French
English
syndication feed
iron overload
iron chelating agents
iron chelating agents
treatment outcome
drug evaluation
drug labeling
drug approval
orphan drug production
chronic disease
blood transfusion
tablets
administration, oral
adult
child
pregnancy
breast feeding
drug interactions
deferasirox
drug evaluation
summary of product characteristics
package leaflet
Deferasirox
Deferasirox
---
http://www.cochrane.org/fr/CD007477
2012
false
United Kingdom
France
French
french abstract
blood transfusion
anemia, sickle cell
iron chelating agents
treatment outcome
review of literature
iron overload
Deferasirox
---
http://www.cochrane.org/fr/CD007476
http://www.cochrane.org/fr/CD007476/deferasirox-pour-la-gestion-de-la-surcharge-ferrique-transfusionnelle-chez-les-personnes-atteintes-de-thalassemie
2012
false
true
false
United Kingdom
France
iron chelating agents
treatment outcome
deferoxamine
administration, oral
meta-analysis
french abstract
iron overload
thalassemia
Deferasirox
---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00059
2011
false
false
false
Canada
drug information
tablets
Deferasirox
---
http://www.meddispar.fr/medicaments/3769511
2008
France
French
benzoates
continuity of patient care
adult
triazoles
child
drug prescriptions
legislation, drug
administration, oral
tablets
drug monitoring
drug information
Deferasirox
---
http://www.meddispar.fr/medicaments/3769557
2008
France
French
benzoates
iron chelating agents
administration, oral
triazoles
tablets
continuity of patient care
drug monitoring
drug prescriptions
legislation, drug
adult
child
deferasirox
drug information
Deferasirox
---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Exjade_final_fr.pdf
2007
false
Canada
French
iron overload
iron chelating agents
deferasirox
drug evaluation
Deferasirox
---
