Preferred Label : Ticagrelor;

MeSH definition : An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION.;

MeSH hyponym : AZD6140; AZD-6140;

MeSH CAS label : 1,2-cyclopentanediol, 3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-1,2,3-triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-;

UNII : GLH0314RVC;

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An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION.

http://sfar.org/wp-content/uploads/2018/03/2_Gestion-des-agents-antiplaquettaires-pour-une-procedure-invasive-programmee.pdf
https://doi.org/10.1016/j.anrea.2018.01.002
2018
false
false
false
France
French
platelet aggregation inhibitors
hemorrhage
postoperative complications
platelet aggregation inhibitors
embolism and thrombosis
aspirin
administration, oral
Prasugrel Hydrochloride
risk management
risk assessment
continuity of patient care
patient safety
purinergic P2Y receptor antagonists
purinergic P2Y receptor antagonists
platelet aggregation inhibitors excl. heparin
surgical procedures, operative
blood loss, surgical
perioperative period
ticlopidine
ticlopidine
adenosine
adenosine
Clopidogrel
Ticagrelor

---
https://www.has-sante.fr/portail/jcms/c_2847928/fr/brilique
2018
false
false
false
false
France
French
evaluation of the transparency committee
Brilique
adenosine
Ticagrelor

---
http://www.has-sante.fr/portail/jcms/c_2744502/fr/brilique
https://www.has-sante.fr/portail/jcms/c_2744502/fr/brilique-60-mg-ticagrelor-antiagregant-plaquettaire
2017
false
false
France
French
myocardial infarction
Atherothrombosis
guidelines for drug use
drug therapy, combination
aspirin
adult
thrombosis
atherosclerosis
ticagrelor
insurance, health, reimbursement
administration, oral
platelet aggregation inhibitors
platelet aggregation inhibitors
purinergic P2Y receptor antagonists
purinergic P2Y receptor antagonists
adenosine
aged
treatment outcome
evaluation of the transparency committee
Ticagrelor
Ticagrelor

---
https://www.has-sante.fr/portail/jcms/c_2800626/fr/brilique
2017
false
false
false
false
France
French
evaluation of the transparency committee
Brilique
adenosine
Ticagrelor

---
http://www.has-sante.fr/portail/jcms/c_1710205/fr/antiagregants-plaquettaires-prise-en-compte-des-risques-thrombotique-et-hemorragique-pour-les-gestes-percutanes-chez-le-coronarien
http://www.has-sante.fr/portail/upload/docs/application/pdf/2013-12/recommandations_antiagregants_plaquettaires_-_gestes_percutanes.pdf
http://www.has-sante.fr/portail/jcms/c_1710202/fr/fiche-de-synthese-antiagregants-plaquettaires-gestes-percutanes
2013
true
France
French
CORONARY STENT, OTHER
Prasugrel Hydrochloride
Prasugrel Hydrochloride
platelet aggregation inhibitors
platelet aggregation inhibitors
coronary disease
hemorrhage
risk management
guidelines for drug use
injections, Intra-Articular
bone marrow examination
biopsy
aspirin
aspirin
platelet aggregation inhibitors excl. heparin
thrombosis
punctures
biopsy, needle
cementoplasty
biopsy, Large-Core needle
biopsy, fine-needle
spinal puncture
nephrostomy, percutaneous
drug combinations
dipyridamole
administration, oral
pravastatin
risk assessment
practice guideline
angioplasty
chest tubes
stents
ticlopidine
adenosine
Clopidogrel
Clopidogrel
Ticagrelor
Ticagrelor

---
https://www.ema.europa.eu/medicines/human/EPAR/Possia
2012
United Kingdom
French
syndication feed
drug approval
treatment outcome
drug interactions
pregnancy
adenosine
administration, oral
atherosclerosis
thrombosis
ticagrelor
drug therapy, combination
platelet aggregation inhibitors
platelet aggregation inhibitors
adult
myocardial infarction
angina, unstable
stroke
myocardial infarction
purinergic P2Y receptor antagonists
purinergic P2Y receptor antagonists
drug evaluation
summary of product characteristics
package leaflet
Ticagrelor
Ticagrelor

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61958462
2012
France
summary of product characteristics
package leaflet
tablets
Brilique
Ticagrelor

---
https://www.ema.europa.eu/medicines/human/EPAR/Brilique
2012
United Kingdom
French
syndication feed
drug approval
ticagrelor
drug therapy, combination
treatment outcome
platelet aggregation inhibitors
platelet aggregation inhibitors
adult
thrombosis
atherosclerosis
acute coronary syndrome
administration, oral
pregnancy
drug interactions
purinergic P2Y receptor antagonists
purinergic P2Y receptor antagonists
adenosine
drug evaluation
summary of product characteristics
package leaflet
aspirin
Ticagrelor
Ticagrelor

---
https://www.inesss.qc.ca/thematiques/medicaments/medicaments-evaluation-aux-fins-dinscription/extrait-davis-au-ministre/brilinta-1420.html
2012
false
Canada
English
French
CORONARY STENT, OTHER
evaluation of the transparency committee
acute coronary syndrome
administration, oral
treatment outcome
Cost-Benefit analysis
purinergic P2Y receptor antagonists
adenosine
ticagrelor
platelet aggregation inhibitors
drug therapy, combination
thrombosis
atherosclerosis
clinical trials as topic
aspirin
drug evaluation
Ticagrelor

---
Summary Basis of Decision (SBD) for BRILINTA - Ticagrelor, 90 mg tablet
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00021
2011
false
Canada
French
English
CORONARY STENT, OTHER
administration, oral
drug approval
treatment outcome
risk assessment
ticagrelor
adenosine
drug therapy, combination
aspirin
platelet aggregation inhibitors
platelet aggregation inhibitors
acute coronary syndrome
thrombosis
atherosclerosis
purinergic P2Y receptor antagonists
purinergic P2Y receptor antagonists
clinical trials as topic
drug evaluation
Ticagrelor
Ticagrelor

---
http://www.has-sante.fr/portail/jcms/c_1230716/brilique-07122011-synthese-ct10968
http://www.has-sante.fr/portail/jcms/c_1173059/brilique-07-12-2011-avis-ct10968
http://www.has-sante.fr/portail/jcms/c_1230762/brilique-ticagrelor-antiagregant-plaquettaire-synthese-d-avis
2011
France
French
drug therapy, combination
aspirin
acute coronary syndrome
adult
thrombosis
atherosclerosis
ticagrelor
insurance, health, reimbursement
administration, oral
platelet aggregation inhibitors
platelet aggregation inhibitors
purinergic P2Y receptor antagonists
purinergic P2Y receptor antagonists
adenosine
aged
treatment outcome
clinical trials, phase iii as topic
comparative study
guidelines for drug use
evaluation of the transparency committee
Ticagrelor
Ticagrelor

---
http://www.has-sante.fr/portail/jcms/c_1172422/brilique
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-01/brilique_07-12-2011_avis_ct10968.pdf
2011
France
French
evaluation of the transparency committee
administration, oral
ticagrelor
insurance, health, reimbursement
clinical trials as topic
platelet aggregation inhibitors
platelet aggregation inhibitors
purinergic P2Y receptor antagonists
purinergic P2Y receptor antagonists
adenosine
adult
drug therapy, combination
acute coronary syndrome
myocardial infarction
atherosclerosis
thrombosis
multicenter studies as topic
comparative study
Ticagrelor
Ticagrelor

---
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02/06/2024


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