Orlistat - CISMeF

Preferred Label : Orlistat;

MeSH definition : A lactone derivative of LEUCINE that acts as a pancreatic lipase inhibitor to limit the absorption of dietary fat; it is used in the management of obesity.;

MeSH synonym : Tetrahydrolipstatin; THLP; Tetrahydrolipastatin;

MeSH hyponym : Ro 18 0647;

MeSH CAS label : L-Leucine, N-formyl-, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl ester, (2S-(2alpha(R*),3beta))-;

MeSH Related Number : 96829-58-2 (Orlistat);

UNII : 95M8R751W8;

Details

Origin ID

D000077403;

UMLS CUI

C0076275;

ATC code(s)
- orlistat [ATC Code]
- peripherally acting antiobesity products [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- THL-P [NCIt concept]
CISMeF manual mappings
- orlistat [Substance BNPC]
MeSH indexing information
- lipase [MeSH Descriptor]
Pharmacological action(s)
- anti-obesity agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
- lipid regulating agents [MeSH Descriptor]
Record concept(s)
- 1-((3-Hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate [MeSH concept]
- Ro-18-0647 [MeSH concept]
- alli [MeSH concept]
- orlistat [MeSH concept]
- xenical [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Orlistat [NCIt concept]
- Orlistat (substance) [SNOMED CT concept]
- Product containing orlistat (medicinal product) [SNOMED CT concept]
- orlistat [ATC Code]
- orlistat [Substance BNPC]
Validated automatic mappings to BTNT
- orlistat [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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