Preferred Label : Rimonabant;

MeSH definition : A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.;

MeSH hyponym : SR 141716; N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride; SR-141716A; SR141716A;

MeSH CAS label : 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-;

MeSH Related Number : 158681-13-1 (Rimonabant); HL0V2LQZ09;

UNII : RML78EN3XE;

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A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.

http://www.cochrane.org/fr/CD007654/les-effets-long-terme-des-medicaments-amaigrissants-chez-les-personnes-presentant-une-elevation-de
2016
false
United Kingdom
France
French
meta-analysis
treatment outcome
hypertension
anti-obesity agents
overweight
appetite depressants
lactones
sibutramine
piperidines
pyrazoles
cyclobutanes
french abstract
Rimonabant
Orlistat

---
https://ansm.sante.fr/uploads/2021/03/12/c835152be826211f48087f6b4797d072.pdf
2012
false
false
false
France
guidelines for drug use
rimonabant
delivery, obstetric
public health
homeopathy
Rimonabant

---
http://www.cbip.be/pdf/tft/TF_OBES.pdf
2010
Belgium
French
pediatric obesity
obesity
obesity
obesity
treatment outcome
weight loss
diet, reducing
exercise
obesity
obesity
appetite depressants
anti-obesity agents
appetite depressants
anti-obesity agents
bariatric surgery
Outcome Assessment, Health Care
child
adolescent
sibutramine
lactones
cyclobutanes
piperidines
pyrazoles
practice guideline
table
Rimonabant
Orlistat

---
http://www.cbip.be/Folia/Index.cfm?FoliaWelk=F35F11D
2008
Belgium
drug information
product recalls and withdrawals
rimonabant
Rimonabant

---
https://www.ema.europa.eu/medicines/human/EPAR/Zimulti
2008
United Kingdom
English
French
syndication feed
drug evaluation
obesity
piperidines
pyrazoles
treatment outcome
piperidines
pyrazoles
anti-obesity agents
adult
pregnancy
breast feeding
tablets
administration, oral
drug evaluation, preclinical
risk factors
drug interactions
piperidines
pyrazoles
piperidines
piperidines
pyrazoles
pyrazoles
piperidines
pyrazoles
piperidines
pyrazoles
receptor, cannabinoid, CB1
rimonabant
piperidines
pyrazoles
drug evaluation
package leaflet
summary of product characteristics
Rimonabant

---
https://centres-antipoison.net/wp-content/uploads/2017/08/rapport_CCTV_Rimonabant_2008.pdf
2008
France
French
technical report
drug information
piperidines
product surveillance, postmarketing
piperidines
pyrazoles
pyrazoles
retrospective studies
acute disease
receptors, cannabinoid
anti-obesity agents
anti-obesity agents
france
data collection
Drug-Related side effects and adverse reactions
Rimonabant
Rimonabant

---
https://rmlg.uliege.be/article/1699
2008
Belgium
French
piperidines
pyrazoles
receptor, cannabinoid, CB1
journal article
Rimonabant

---
https://www.ema.europa.eu/medicines/human/EPAR/Acomplia
2008
United Kingdom
French
English
syndication feed
Contraindications, Procedure
obesity
piperidines
piperidines
pyrazoles
pyrazoles
receptor, cannabinoid, CB1
drug evaluation
treatment outcome
adult
tablets
administration, oral
piperidines
pyrazoles
anti-obesity agents
piperidines
pyrazoles
piperidines
piperidines
pyrazoles
pyrazoles
risk factors
drug interactions
pregnancy
breast feeding
pyrazoles
piperidines
pyrazoles
piperidines
drug evaluation, preclinical
rimonabant
piperidines
pyrazoles
drug evaluation
package leaflet
summary of product characteristics
Contraindications, Drug
Rimonabant

---
http://www.lecrat.eu/?s=Rimonabant+-+Acomplia%C2%AE
2007
France
French
pregnancy
breast feeding
receptors, cannabinoid
piperidines
pyrazoles
anti-obesity agents
rimonabant
piperidines
pyrazoles
drug information
Rimonabant

---
http://revmed.ch/RMS/2006/RMS-76/31614
2006
true
Switzerland
French
piperidines
pyrazoles
obesity
overweight
anti-obesity agents
randomized controlled trials as topic
Metabolic Syndrome
receptor, cannabinoid, CB1
treatment outcome
rimonabant
piperidines
pyrazoles
journal article
drug information
Rimonabant

---
http://revmed.ch/RMS/2006/RMS-47/30911
2006
journal article
obesity
rimonabant
Metabolic Syndrome
obesity
Rimonabant

---
https://minerva-ebp.be/fr/article/637
2006
false
false
minerva-ebm.be
Belgium
French
weight loss
obesity
treatment outcome
piperidines
pyrazoles
cardiovascular diseases
risk factors
receptor, cannabinoid, CB1
adult
piperidines
pyrazoles
critical appraisal or critical reading
Rimonabant

---
https://www.amub-ulb.be/system/files/rmb/old/166
2005
journal article
rimonabant
endocannabinoids
Rimonabant

---
https://www.amub-ulb.be/system/files/rmb/old/192
2005
false
Belgium
French
Ezetimibe
hypolipidemic agents
fatty acids, Omega-3
piperidines
niacin
anticholesteremic agents
pyrazoles
docosahexaenoic acids
eicosapentaenoic acid
Omacor
drug combinations
journal article
Rimonabant

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03/05/2025


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