Troglitazone - CISMeF

Preferred Label : Troglitazone;

MeSH definition : A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.;

MeSH synonym : 5-(4-((6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione) - T;

MeSH hyponym : CS-045; CS045;

MeSH CAS label : 2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-;

MeSH Related Number : 97322-87-7 (Troglitazone);

UNII : I66ZZ0ZN0E;

Details

Origin ID

D000077288;

UMLS CUI

C0245514;

ATC code(s)
- troglitazone [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Troglitazone [ICD-11 Extension code]
MeSH indexing information
- antineoplastic agents [MeSH Descriptor]
- fibrinolytic agents [MeSH Descriptor]
- peroxisome proliferator-activated receptors [MeSH Descriptor]
- platelet aggregation inhibitors [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Pharmacological action(s)
- hypoglycemic agents [MeSH Descriptor]
Record concept(s)
- CS 045 [MeSH concept]
- Troglitazone [MeSH concept]
- prelay [MeSH concept]
- rezulin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 5-(4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)-2,4-dioxothiazollidine, troglitazone dihydrate [MeSH Supplementary Concept]
- troglitazone sulfate [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing troglitazone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing troglitazone (medicinal product) [SNOMED CT concept]
- Troglitazone [NCIt concept]
- Troglitazone (substance) [SNOMED CT concept]
- troglitazone [ATC Code]
Validated automatic mappings to BTNT
- troglitazone [ATC Code]

Keyword's position in hierarchy(ies) :

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