Troglitazone - CISMeF

Preferred Label : Troglitazone;

NCIt synonyms : 5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione; 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-2,4-Thiazolidinedione;

NCIt definition : An orally-active thiazolidinedione with antidiabetic and hepatotoxic properties and potential antineoplastic activity. Troglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. (NCI04);

UNII : I66ZZ0ZN0E;

CAS number : 97322-87-7;

Drug name : Rezulin; Prelay; Romozin;

Molecule name : CS-045; CI-991;

ChEBI ID : CHEBI:9753;

Codes from synonyms : 09341;

Details

Origin ID

C1522;

UMLS CUI

C0245514;

Automatic exact mappings (from CISMeF team)
- Troglitazone [ICD-11 Extension code]
CISMeF manual mappings
- Troglitazone [MeSH concept]
See also inter- (CISMeF)
- Product containing troglitazone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing troglitazone (medicinal product) [SNOMED CT concept]
- Troglitazone [MeSH Descriptor]
- Troglitazone (substance) [SNOMED CT concept]
- troglitazone [ATC Code]
Validated automatic mappings to BTNT
- troglitazone [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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