Preferred Label : Troglitazone;
NCIt synonyms : 5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione; 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-2,4-Thiazolidinedione;
NCIt definition : An orally-active thiazolidinedione with antidiabetic and hepatotoxic properties and
potential antineoplastic activity. Troglitazone activates peroxisome proliferator-activated
receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing
cell differentiation and inhibiting cell growth and angiogenesis. This agent also
modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte
activation, and stimulates adipocyte differentiation. (NCI04);
UNII : I66ZZ0ZN0E;
CAS number : 97322-87-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 97322-87-7
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G-SRS /a ;
Drug name : Rezulin; Prelay; Romozin;
Molecule name : CS-045; CI-991;
ChEBI ID : CHEBI:9753;
Codes from synonyms : 09341;
Origin ID : C1522;
UMLS CUI : C0245514;
Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
