Decitabine - CISMeF

Preferred Label : Decitabine;

MeSH definition : An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.;

MeSH synonym : 5-Aza-2'-deoxycytidine; 5 Aza 2' deoxycytidine; 5-AzadC; AzadC Compound; Compound, AzadC; 5AzadC; 2'-Deoxy-5-azacytidine; 2' Deoxy 5 azacytidine; 5-Azadeoxycytidine; 5 Azadeoxycytidine;

MeSH hyponym : NSC-127716; NSC127716; Mesylate, Decitabine;

Related MeSH term : 5 Deoxyazacytidine;

MeSH Related Number : 2353-33-5 (Decitabine); 6U3LPL9PRN;

Wikipedia link : https://en.wikipedia.org/wiki/Decitabine;

UNII : 776B62CQ27;

Details

Origin ID

D000077209;

UMLS CUI

C0049065;

ATC code(s)
- decitabine [ATC Code]
- decitabine, combinations [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Decitabine [ICD-11 Extension code]
CISMeF manual mappings
- 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-1,3,5-triazin-2(1h)-one [Substance BNPC]
MeSH indexing information
- DNA modification methylases [MeSH Descriptor]
- myelodysplastic syndromes [MeSH Descriptor]
Pharmacological action(s)
- antimetabolites, antineoplastic [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- 5-Deoxyazacytidine [MeSH concept]
- NSC 127716 [MeSH concept]
- dacogen [MeSH concept]
- decitabine [MeSH concept]
- decitabine mesylate [MeSH concept]
Related MeSH Supplementary Concept(s)
- decitabine and cedazuridine drug combination [MeSH Supplementary Concept]
See also
- cytarabine [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing decitabine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- decitabine [ATC Code]

Keyword's position in hierarchy(ies) :

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