Survivin - CISMeF

Preferred Label : Survivin;

MeSH definition : An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.;

MeSH synonym : BIRC5 Protein; Baculoviral IAP Repeat-containing Protein 5; Baculoviral IAP Repeat containing Protein 5;

Wikipedia link : https://en.wikipedia.org/wiki/Survivin;

Details

Origin ID

D000077022;

UMLS CUI

C0664336;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- BIRC5 wt Allele [NCIt concept]
- Baculoviral IAP Repeat-Containing Protein 5 [NCIt concept]
- Baculoviral iap repeat-containing protein 5 [OMIM gene]
Record concept(s)
- Survivin [MeSH concept]
Related MeSH Supplementary Concept(s)
- BIRC5 protein, human [MeSH Supplementary Concept]
- Bir1 protein, S pombe [MeSH Supplementary Concept]
- Birc5 protein, mouse [MeSH Supplementary Concept]
- Birc5 protein, rat [MeSH Supplementary Concept]
- Birc5a protein, zebrafish [MeSH Supplementary Concept]
- HIV-TAT-survivin (T34A) protein [MeSH Supplementary Concept]
- birc5.2 protein, Xenopus [MeSH Supplementary Concept]
- det protein, drosophila [MeSH Supplementary Concept]
- survivin protein, xenopus laevis [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Survivin Antigen [NCIt concept]

Keyword's position in hierarchy(ies) :

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