Disks Large Homolog 4 Protein

Preferred Label : Disks Large Homolog 4 Protein;

MeSH definition : A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.;

MeSH synonym : Postsynaptic Density Protein 95; Discs Large Homolog 4 Protein; SAP-90 Protein; SAP 90 Protein; PSD95 Protein; PSD-95 Protein; PSD 95 Protein; Synapse-Associated Protein 90; Synapse Associated Protein 90; SAP90 Protein;

Details

Origin ID

D000076122;

UMLS CUI

C4318444;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Discs large maguk scaffold protein 4 [OMIM gene]
- Disks Large Homolog 4 [NCIt concept]
Record concept(s)
- Disks Large Homolog 4 Protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- DLG4 protein, human [MeSH Supplementary Concept]
- Dlg4 protein, mouse [MeSH Supplementary Concept]
- Dlg4 protein, rat [MeSH Supplementary Concept]
See also
- SAP90-PSD95 Associated Proteins [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients