Baculoviral IAP Repeat-Containing 3 Protein

Preferred Label : Baculoviral IAP Repeat-Containing 3 Protein;

MeSH definition : A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells.;

MeSH synonym : Baculoviral IAP Repeat Containing 3 Protein; Apoptosis Inhibitor 2; Inhibitor 2, Apoptosis; Inhibitor of Apoptosis Protein 1; cIAP2 Protein; c-IAP2 Protein; Cellular Inhibitor of Apoptosis-2; Apoptosis-2 Cellular Inhibitor; Cellular Inhibitor of Apoptosis 2; Baculoviral IAP Repeat Containing Protein 3; Inhibitor of Apoptosis 1 Protein; IAP1 Protein; BIRC3 Protein; Hiap-1 Protein; Hiap 1 Protein;

Registry Number MeSH : EC 2.3.2.27;

UNII : EC 2.3.2.27;

Details

Origin ID

D000075747;

UMLS CUI

C4317102;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- BIRC3 wt Allele [NCIt concept]
- Baculoviral IAP Repeat-Containing Protein 3 [NCIt concept]
- Baculoviral iap repeat-containing protein 3 [OMIM gene]
- baculoviral IAP repeat containing 3 [ORDO Gene]
- baculoviral IAP repeat containing 3 [HGNC gene]
Pharmacological action(s)
- caspase inhibitors [MeSH Descriptor]
Record concept(s)
- Baculoviral IAP Repeat-Containing 3 Protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- BIRC3 protein, human [MeSH Supplementary Concept]
- Birc3 protein, mouse [MeSH Supplementary Concept]
- Birc3 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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