" /> Positive Regulatory Domain I-Binding Factor 1 - CISMeF





Preferred Label : Positive Regulatory Domain I-Binding Factor 1;

MeSH definition : A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.;

MeSH synonym : Positive Regulatory Domain I Binding Factor 1; PRDI-BF1 Protein; PRDI BF1 Protein; B Lymphocyte-Induced Maturation Protein 1; B Lymphocyte Induced Maturation Protein 1; PRDM1 Protein; BLIMP1 Protein;

Registry Number MeSH : EC 2.1.1.-;

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A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.

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19/05/2024


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