Connexin 26 - CISMeF

Preferred Label : Connexin 26;

MeSH definition : A gap junction protein encoded by the Gap Junction Beta 2 or GJB2 gene. In the cochlea and epidermis, its hexamers form channels between cells that open to allow cell-to-cell diffusion of small molecules as well as recycling of potassium. Mutations in Connexin 26 are associated with congenital SENSORINEURAL HEARING LOSS.;

MeSH synonym : 26, Connexin; beta2 Connexin; Connexin, beta2; Connexin beta-2; Connexin beta 2; beta-2, Connexin; Connexin Cx26; Cx26, Connexin;

DeCS synonym : Gap Junction beta-2 protein;

MeSH hyponym : Gap Junction beta 2 protein;

Registry Number MeSH : 127120-53-0;

Wikipedia link : https://en.wikipedia.org/wiki/Connexin 26;

Details

Origin ID

D000072259;

UMLS CUI

C0163742;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Gap Junction Beta-2 Protein [NCIt concept]
- Gap junction protein, beta-2 [OMIM gene]
- gap junction protein beta 2 [ORDO Gene]
- gap junction protein beta 2 [HGNC gene]
Currated CISMeF NLP mapping
- Connexin 26 [FMA entity]
Record concept(s)
- Gap Junction beta-2 protein [MeSH concept]
- connexin 26 [MeSH concept]
Related MeSH Supplementary Concept(s)
- GJB2 protein, Xenopus [MeSH Supplementary Concept]
- GJB2 protein, human [MeSH Supplementary Concept]
- Gjb2 protein, mouse [MeSH Supplementary Concept]
- Gjb2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Connexin 26 [FMA entity]

Keyword's position in hierarchy(ies) :

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