Stromal Interaction Molecule 1

Preferred Label : Stromal Interaction Molecule 1;

MeSH definition : A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.;

MeSH synonym : STIM1 Protein;

Wikipedia link : https://en.wikipedia.org/wiki/Stromal interaction molecule 1;

Details

Origin ID

D000071737;

UMLS CUI

C4255328;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- STIM1 Gene [NCIt concept]
- Stromal Interaction Molecule 1 [NCIt concept]
- Stromal interaction molecule 1 [OMIM gene]
- stromal interaction molecule 1 [ORDO Gene]
- stromal interaction molecule 1 [HGNC gene]
Record concept(s)
- Stromal Interaction Molecule 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- STIM1 protein, Xenopus [MeSH Supplementary Concept]
- STIM1 protein, human [MeSH Supplementary Concept]
- Stim protein, Drosophila [MeSH Supplementary Concept]
- Stim1 protein, mouse [MeSH Supplementary Concept]
- Stim1 protein, rat [MeSH Supplementary Concept]
- stim-1 protein, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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