X-Box Binding Protein 1

Preferred Label : X-Box Binding Protein 1;

MeSH definition : A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.;

MeSH synonym : X Box Binding Protein 1; TREB5 Protein; Tax-Responsive Element-Binding Protein 5; Tax Responsive Element Binding Protein 5; XBP-1 Protein; XBP 1 Protein; TREB-5 Protein; TREB 5 Protein; XBP2 Protein;

Details

Origin ID

D000071717;

UMLS CUI

C2825104;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- X-Box Binding Protein 1 [NCIt concept]
- X-box binding protein 1 [HGNC gene]
- XBP1 Gene [NCIt concept]
Record concept(s)
- X-Box Binding Protein 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- XBP1 protein, human [MeSH Supplementary Concept]
- Xbp1 protein, mouse [MeSH Supplementary Concept]
- Xbp1 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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