Cytochrome p450, subfamily I, polypeptide 2

Preferred Label : Cytochrome p450, subfamily I, polypeptide 2;

Symbol : CYP1A2;

CISMeF acronym : CYP1A2;

Type : Gene and phenotype, combined;

Alternative titles and symbols : Cytochrome p-450, aromatic compound-inducible; Dioxin-inducible p3-450;

Included titles and symbols : Phenacetin metabolism, defect in; Phenacetin o-deethylase, deficiency of;

Description : The CYP1A2 gene encodes a P450 enzyme involved in O-deethylation of phenacetin. It is 1 of several forms of cytochrome P-450 that have been purified to electrophoretic homogeneity from human liver microsomes (Guengerich et al., 1986). P1-450 (CYP1A1; 108330) and P3-450 are 2 members of the dioxin-inducible P450 gene family.;

Inheritance : Autosomal dominant (15q22-qter);

Prefixed ID : 124060;

Details

Origin ID

124060;

UMLS CUI

C1332826;

Automatic exact mappings (from CISMeF team)
- CYP1A2 gene [LOINC component]
- cytochrome P-450 CYP1A2 [MeSH concept]
- cytochrome P450 family 1 subfamily A member 2 [HGNC gene]
- cytochrome p-450 cyp1a2 [MeSH Descriptor]
- phenacetin O-Deethylase, deficiency of [MeSH concept]
- phenacetin O-Deethylase, deficiency of [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- CYP1A2 Gene [NCIt concept]
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450, family 1, subfamily A, polypeptide 2 [ORDO Gene]
- Cytochrome p450 CYP1A2 enzyme (substance) [SNOMED CT concept]
NCIt concept(s)
- CYP1A2 Gene [NCIt concept]
- CYP1A2 wt Allele [NCIt concept]
- CYP1A2*1 Allele [NCIt concept]
- CYP1A2*11 Allele [NCIt concept]
- CYP1A2*7 Allele [NCIt concept]
- Cytochrome P450 1A2 [NCIt concept]
ORDO concept(s)
- Cytochrome P450, family 1, subfamily A, polypeptide 2 [ORDO Gene]
- cytochrome P450 family 1 subfamily A member 2 [ORDO Gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- CYP1A2 Gene [NCIt concept]
- CYP1A2 gene [LOINC component]
- cytochrome P450 family 1 subfamily A member 2 [HGNC gene]

Keyword's position in hierarchy(ies) :

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