Preferred Label : rate-determining step;
Detailed label : rate-determining step (rate-limiting step);
IUPAC definition : These terms are best regarded as synonymous with rate-controlling step. However, other
meanings that have been given to them should be mentioned, as it is necessary to be
aware of them in order to avoid confusion. Sometimes the term rate-determining is
used as a special case of rate-controlling, being assigned only to an initial slow
step which is followed by rapid steps. Such a step imposes an upper limit on the rate,
and has also been called rate-limiting. In view of the considerable danger of confusion
when special meanings are applied to rate-determining and rate-limiting, it is recommended
that they be regarded as synonymous, with the meaning explained under the entry rate-controlling
step.;
Origin ID : R05140;
See also
These terms are best regarded as synonymous with rate-controlling step. However, other
meanings that have been given to them should be mentioned, as it is necessary to be
aware of them in order to avoid confusion. Sometimes the term rate-determining is
used as a special case of rate-controlling, being assigned only to an initial slow
step which is followed by rapid steps. Such a step imposes an upper limit on the rate,
and has also been called rate-limiting. In view of the considerable danger of confusion
when special meanings are applied to rate-determining and rate-limiting, it is recommended
that they be regarded as synonymous, with the meaning explained under the entry rate-controlling
step.
