ICD-11 code : 2B31.2;
Preferred Label : Langerhans cell histiocytosis;
ICD-11 definition : A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural
examination. Three major overlapping syndromes are recognized: eosinophilic granuloma,
Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is
generally related to the number of organs affected at presentation.;
ICD-11 synonym : Langerhans-cell histiocytosis NOS;
ICD-11 inclusion : Histiocytosis X;
ICD-11 "other" category code : 2B31.2Y;
Origin ID : 216625985;
Automatic exact mappings (from CISMeF team)
A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural
examination. Three major overlapping syndromes are recognized: eosinophilic granuloma,
Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is
generally related to the number of organs affected at presentation.