integrin alpha4beta1

Preferred Label : integrin alpha4beta1;

MeSH definition : Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.;

MeSH synonym : alpha4beta1 integrin; antigen-4, very late; cd49d-cd29; heterodimer alpha4beta1, integrin; integrin alpha(4)beta(1); very late activation antigen 4; alpha4beta1, integrin; vla-4; integrin heterodimer alpha4beta1; alpha4beta1, integrin heterodimer; very late activation antigen-4; very late antigen-4; late antigen-4, very; very late antigen 4; integrin, alpha4beta1;

Wikipedia link : https://en.wikipedia.org/wiki/Integrin alpha4beta1;

Is substance : O;

Details

Origin ID

D039041;

UMLS CUI

C0209606;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Currated CISMeF NLP mapping
- Integrin Alpha4/Beta1 [NCIt concept]
Indexing information
- 2-((2,6-dichlorophenyl)carbonylamino)-3-((2,4,8-triaza-2-methyl-1-oxo-4-phenylspiro(4.5)dec-8-yl)carbonylamino)propanoic acid [MeSH Supplementary Concept]
- 3-(1,3-benzodioxol-5-yl)-3-((((-1-((bis(2-thienylmethyl)amino)carbonyl)pentyl)amino)carbonyl)amino)propanoic acid [MeSH Supplementary Concept]
- 3-(N-(3,4-dimethoxybenzyl)-2-(2-(3-methoxy-4-(3-o-tolylureido)phenyl)acetylamino)acetamido)propanoic acid [MeSH Supplementary Concept]
- 4-((2-(2-methylphenylamino)-6-benzoxazolylacetyl)-4-fluoro-2-pyrrolidinylmethoxy)cyclohexanecarboxylic acid [MeSH Supplementary Concept]
- 4-(1-(3-chloro-4-(N-(2-methylphenyl)ureido)phenylacetyl)-4-fluoropyrrolidine-2-yl)methoxybenzoic acid [MeSH Supplementary Concept]
- IVL 984 [MeSH Supplementary Concept]
- S 16197 [MeSH Supplementary Concept]
- S 18407 [MeSH Supplementary Concept]
- S 3429 [MeSH Supplementary Concept]
- trans-4-(1-((2,5-dichloro-4-(1-methyl-3-indolylcarboxyamide)phenyl)acetyl)-(4S)-methoxy-(2S)-pyrrolidinylmethoxy)cyclohexanecarboxylic acid [MeSH Supplementary Concept]
Record concept(s)
- integrin alpha4beta1 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Integrin Alpha4/Beta1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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