Preferred Label : RNA 5' terminal oligopyrimidine sequence;
MeSH definition : A regulatory sequence found in the 5' terminal regions of a variety of RNA species.
The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE
NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is
often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and
has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.;
MeSH synonym : rna 5' terminal oligopyrimidine regulatory sequence; sequence, 5' top; sequences, 5' top; 5' top sequence; 5' top sequences;
Related MeSH term : 5' TOP mRNA; 5' TOP Messenger RNA;
Is substance : O;
Origin ID : D038641;
UMLS CUI : C1138415;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
A regulatory sequence found in the 5' terminal regions of a variety of RNA species.
The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE
NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is
often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and
has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
