tissue inhibitor of metalloproteinase-1

Preferred Label : tissue inhibitor of metalloproteinase-1;

MeSH definition : A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.;

MeSH synonym : timp-1; metalloproteinase-1 tissue inhibitor; tissue inhibitor of metalloproteinase 1;

Is substance : O;

Details

Origin ID

D019715;

UMLS CUI

C0145947;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- TIMP1 Gene [NCIt concept]
- Tissue inhibitor of metalloproteinase 1 [OMIM gene]
Pharmacological action(s)
- matrix metalloproteinase inhibitors [MeSH Descriptor]
Record concept(s)
- tissue inhibitor of Metalloproteinase-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TIMP1 protein, human [MeSH Supplementary Concept]
- TIMP1 protein, rat [MeSH Supplementary Concept]
- Timp1 protein, mouse [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Tissue Inhibitor of Metalloproteinase 1 Measurement [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Tissue inhibitor of metalloproteinases 1 [LOINC component]
- Tissue inhibitor of metalloproteinases 1 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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