Preferred Label : ATP Binding Cassette Transporter, Subfamily A;
MeSH definition : A large, highly conserved, subfamily of ATP binding cassette transporters structurally
characterized by a membrane-spanning domain composed of six ALPHA-HELICES, a large
extracellular loop, nucleotide-binding domain, and a conserved cytoplasmic 80 amino
acid sequence. In humans, it includes ABCA1(ATP BINDING CASSETTE TRANSPORTER 1) through
ABCA10, as well as ABCA12 and ABCA13.;
MeSH synonym : ATP Binding Cassette Transporter, Sub Family A; ABCA Transporters; Transporters, ABCA; ATP Binding Cassette Transporter, Sub-Family A;
Origin ID : D000073874;
UMLS CUI : C4505140;
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Record concept(s)
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A large, highly conserved, subfamily of ATP binding cassette transporters structurally
characterized by a membrane-spanning domain composed of six ALPHA-HELICES, a large
extracellular loop, nucleotide-binding domain, and a conserved cytoplasmic 80 amino
acid sequence. In humans, it includes ABCA1(ATP BINDING CASSETTE TRANSPORTER 1) through
ABCA10, as well as ABCA12 and ABCA13.