" /> C2 Domains - CISMeF





Preferred Label : C2 Domains;

MeSH definition : Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE.;

MeSH synonym : Domain, C2; Domains, C2; C2 Domain;

DeCS synonym : C2 Tensin-type Domain;

MeSH hyponym : C2 Tensin type Domain; C2 Tensin-type Domains; Domain, C2 Tensin-type; Domains, C2 Tensin-type; Tensin-type Domain, C2; Tensin-type Domains, C2;

Wikipedia link : https://en.wikipedia.org/wiki/C2 domains;

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Keyword's position in hierarchy(ies) : arborescence

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Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE.

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07/06/2025


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