Publication avant impressionPropriété BDBfr

Le Collège national des enseignants de cancérologie (CNEC) : missions, organisation et projets.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38185534
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00488-5
Huguet F
Tlemsani C
Pierga JY
Curtit E
Deluche E
Domblides C
Guimbaud R
Laprie A
Marchal F
Massard C
Spano JP
10.1016/j.bulcan.2023.12.004
The National College of Cancerology Teachers (CNEC) was created in September 1986. Its missions are to develop the teaching of oncology, to promote educational actions in the discipline, to participate in the development of teaching content and the definition of curricula and the control of knowledge for the training of medical students and specialists, to develop and validate educational documents relating to the above teaching, to ensure the representation of oncology teaching to of the National University Council (CNU) and administrative authorities, to ensure and coordinate relations with other university disciplines, scientific societies, national, European, and international professional groups, and to contribute to the development of research in the discipline. The current office was elected in September 2022 for three years.
2
133-141
111
education; enseignement; fst; medical studies; oncologie; oncology; reform; réforme; simulation; études médicales
06
Février
S0007-4551(23)00488-5
publication avant impression
Accès restreint
éditorial
résumé en anglais
humains
universités
programme d'études
étudiant médecine

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RE: “Conversation between a clinical biologist and an artificial intelligence on prostate cancer biomarkers”.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189337
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1849
Daungsupawong H
Wiwanitkit V
10.1684/abc.2023.1849
6
660-661
81
24
Février
abc.2023.1849
publication avant impression
Accès restreint
article de périodique
Mâle
humains
prostate
communication
tumeurs

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La révision de la loi de bioéthique, deux ans après : grands principes et conséquences pour la pratique au laboratoire de biologie de la reproduction.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189359
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1847
Rivet-Danon D
Ly A
Prades-Borio M
Berthaut I
Ogouma-Aworet L
Panissard C
Bachelot G
Lévy R
Dupont C
Sermondade N
10.1684/abc.2023.1847
Since 1994, in France, bioethics law has set the regulatory framework for Medically Assisted Reproduction (MAR). The latest revision of the law of August 2, 2021, is characterized by major upheavals in the field of MAR and intervenes in several areas: the purpose and conditions to access to MAR, access to origins in the case of gamete or embryo donation, and gametes cryopreservation without medical indication. Indeed, the law authorizes, because of a strong societal demand, the extension of sperm donation to couples of women and unmarried women, as well as the possibility for any person to preserve his/her gametes if he/she meets the age criteria defined by decree. Finally, the law opens the possibility for people born following gamete or embryo donation to have access, from their 18th anniversary, to identifying and/or non-identifying data. These new measures have led to a very important number of MAR requests to fertility and donation centers, and have required the implementation of new circuits in order to harmonize care, without discrimination or prioritization.
6
621-627
81
anonymity; assisted reproductive technologies; bioethics law; gamete donation; sperm donation
24
Février
abc.2023.1847
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Mâle
Femelle
techniques de reproduction assistée
mise à disposition d'embryon
sperme
bioéthique
biologie

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Un bilan alarmant : un plasma sanglant !
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189363
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1850
Labasque J
Marchand D
Lhomme C
Lavisse J
Maboudou P
Grzych G
10.1684/abc.2023.1850
A 35-year-old patient with a metabolic pathology was hospitalized for programmed fibroscopy under general anesthesia for investigation and management of portal hypertension. Following the operation, he showed signs of sepsis and was transferred to intensive care unit. Biological analyzes carried out and generated automaton alarms for certain parameters. A visual check of the appearance of the sample revealed an unusual color of plasma. Additional informations obtained from the clinical department did not provide any explanation for this coloration. Additional assays confirmed an overdose of vitamin B12 related to the treatment of his pathology and which is responsible for the interference observed. Hence the interest of checking the reaction curves in the event of suspected interference and, if necessary, of making dilutions in order to reduce the effects on the biological assays.
6
653-656
81
biochemistry; cobalamin; colorimetric methods; interference; spectrophotometry
24
Février
abc.2023.1850
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
vitamine B12
Mâle
humains
adulte
vitamine B12

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Découverte d’un phénotype érythrocytaire rare suite à une difficulté de groupage : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189423
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1848
Aissa W
Chouaieb S
Bellil N
Kaabi H
Hmida S
10.1684/abc.2023.1848
ABO typing is essential for preventing ABO incompatibility transfusion reactions. Discrepancy exists when reactions in forward grouping do not match with reverse grouping. Any discrepancies reported should be investigated so that correct blood group is reported minimizing the chances of transfusion reaction. The most common causes of ABO discrepancy are cold autoantibodies and missing serum reactivity. We report a rare alloantibody anti-PP1Pk discovered during the resolution of a grouping difficulty with a positive control. Anti-PP1Pk is associated with hemolytic transfusion reactions. In our observation, we were faced with transfusional impasse because of the unavailability of a national rare blood bank or a compatible donor on the registry of individuals with a rare blood phenotype.
6
645-648
81
anti-pp1pk; blood group discrepancy; blood grouping; rare blood group
24
Février
abc.2023.1848
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
système ABO de groupes sanguins
humains
système ABO de groupes sanguins
transfusion sanguine
groupage sanguin et épreuve de compatibilité croisée
phénotype
donneurs de tissus

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Quelle réponse apporter à un refus obstiné de soins lors de l’accouchement ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190966
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00004-7
Lepercq J
Khoury L
Marcel P
Tsatsaris V
Goffinet F
10.1016/j.gofs.2023.12.009
Our team was confronted with a situation of stubborn refusal of care, including the indication of a cesarean section for an adult patient able to express her wishes. This refusal was formulated during pregnancy follow-up, during the discussion of the birth plan and during delivery, the patient having accepted the indication of a possible emergency cesarean section under general anesthesia only in the occurrence of severe fetal heart rate abnormalities. The impasse forced caregivers to violate the rules of good clinical practice, which indicated the performance of a cesarean section, and to wait for a complication to arise in order to be able to act, taking the risk of intervening too late. This situation has led to direct risks to the health of the mother and the unborn child, without putting the life of either of them in imminent danger. Finally, the time devoted to this patient in a tense organization was to the detriment of the care of other patients.
2
109-113
52
refus de soins; refusal of care; accouchement; cesarean delivery; césarienne; delivery; grossesse; medicolegal; médicolégal; pregnancy
06
Février
S2468-7189(24)00004-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
adulte
grossesse
humains
Femelle
césarienne
prise en charge prénatale
anesthésie générale
Refus du traitement

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Actualisation des indications et des techniques de prise en charge du lymphœdème après chirurgie du cancer du sein.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190967
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00001-1
Azuar AS
Uzan C
Mathelin C
Vignes S
10.1016/j.gofs.2023.12.008
AbstractText Label OBJECTIVES Upper limb lymphedema secondary to breast cancer treatment is the leading cause of lymphedema in France. Despite improved surgical practices and de-escalation of radiotherapy, the risk of lymphedema after breast cancer still affects 5-20% of patients, with this variation depending on the measurement method used and the population studied. Lymphedema has a negative impact on quality of life and body image, and their possible occurrence remains a major concern for all women treated for breast cancer. The Sénologie Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF) asked four specialists in breast surgery or lymphology to prepare a summary on the prevention, medical and surgical management of lymphedema after breast cancer treatment, and to discuss the medical and surgical innovations currently being evaluated. /AbstractText AbstractText Label METHODS This synthesis was based on national and international guidelines on the management of upper limb lymphedema after breast surgery and a recent review of the literature focusing on the years 2020-2023. /AbstractText AbstractText Label RESULTS From a preventive point of view, the restrictive instructions imposed for a long time (reduction in physical activity or the carrying of loads, air travel, exposure to the sun or cold, etc.) have altered patients' quality of life and should no longer be recommended. A good understanding of risk factors enables us to target preventive actions. Examples include obesity, a sedentary lifestyle, axillary clearance, radiotherapy of the axillary fossa in addition to axillary clearance, total mastectomy, taxanes or anti-HER-2 therapies in the adjuvant phase. Resumption of physical activity, minimally invasive axillary surgery, de-escalation of radiotherapy and breast-conserving surgical procedures have all demonstrated their preventive value. When lymphedema does occur, early management, through complete decongestive physiotherapy, can help reduce its volume and prevent its long-term worsening. /AbstractText AbstractText Label CONCLUSION Surgical (lymph node transplants, lympho-vascular anastomoses) and medical (prolymphangiogenic growth factors) approaches to lymphedema treatment are numerous, but require long-term evaluation of their efficacy and adverse effects. /AbstractText
3
142-148
52
breast cancer; compression; drainage; lymphedema; microsurgery
06
Mars
S2468-7189(24)00001-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Femelle
tumeurs du sein
mastectomie
qualité de vie
région mammaire
lymphoedème
lymphoedème

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Peut-on surseoir au curage axillaire en cas de carcinome mammaire invasif avec envahissement ganglionnaire ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190968
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00003-5
Brousse S
Lafond C
Schmitt M
Guillermet S
Molière S
Mathelin C
10.1016/j.gofs.2023.12.010
AbstractText Label OBJECTIVES The indications and modalities of breast and axillary surgery are undergoing profound change, with the aim of personalizing surgical management while avoiding over-treatment. To update best practices for axillary surgery, four questions were selected by the Senology Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF), focusing on 1) the definition and evaluation of targeted axillary dissection (TAD) techniques, 2) the possibility of surgical de-escalation in case of initial lymph node involvement while performing initial surgery, 3) in case of surgery following neo-adjuvant systemic therapy (NAST), 4) contraindications to de-escalation of axillary surgery to allow access to particular adjuvant systemic therapies. /AbstractText AbstractText Label METHODS The Senology Commission based its responses primarily on an analysis of the international literature, clinical practice recommendations and national and international guidelines. /AbstractText AbstractText Label RESULTS 1) TAD is a technique that combines excision of clipped metastatic axillary node(s) and the axillary sentinel lymph nodes (ASLNs). The detection rate and sensitivity are increased but it still needs to be standardized and practices better evaluated. 2) TAD represents an alternative to axillary clearance in cases of metastatic involvement of a single node that can be resected. 3) Neither TAD nor ASLN alone is recommended in France after NAST outside of clinical trials, although it is used in several countries in cases of complete pathological response in the lymph nodes, and when at least 3 lymph nodes have been removed. 4) As some adjuvant targeted therapies are indicated in cases of lymph node invasion of more than 3 lymph nodes, the place of TAD in this context remains to be defined. /AbstractText AbstractText Label CONCLUSION Axillary surgical de-escalation can limit the morbidity of axillary clearance. Having proved that TAD does not reduce patient survival, it will most probably replace axillary clearance in well-defined indications. This will require prior standardization of the method and its indications and contraindications, particularly to enable the use of new targeted therapies. /AbstractText
3
132-141
52
axillary lymph node dissection; breast cancer; cancer du sein; chirurgie; curage axillaire; dissection axillaire ciblée; ganglion sentinelle; sentinel lymph node; surgery; targeted axillary dissection
06
Mars
S2468-7189(24)00003-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Femelle
lymphadénectomie
noeuds lymphatiques
tumeurs du sein
région mammaire
association thérapeutique

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L'insuffisance rénale chronique en Amérique, en Afrique et en Asie: aperçu des coûts et des options de traitement.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218427
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00002-6
Mourchid R
Yassine A
Bellahcen M
Cherrah Y
Serragui S
10.1016/j.pharma.2024.01.002
Chronic kidney disease (CKD) is one of the non-infectious diseases that threaten patients' lives on a daily basis. Its prevalence is high, but under-reported by patients and those living with the disease, as it is silent and asymptomatic in the early stages. Kidney disease increases the risk of heart and vascular disease. These problems can manifest themselves slowly, over a long period of time. Early detection and treatment can often prevent chronic kidney disease from worsening. As kidney disease progresses, it can lead to kidney failure, requiring dialysis or a kidney transplant to stay alive. in this narrative review we will mainly discuss different treatment option costs in different countries and how much they cost healthcare systems in countries in three different continents.
chronic kidney disease (ckd); cost; coût; dialyse; dialyse péritonéale; dialysis; hemodialysis; hémodialyse; maladie rénale chronique (mrc); options de traitement; peritoneal dialysis; treatment options
11
Janvier
S0003-4509(24)00002-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

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Évolution du taux d’épisiotomies et des lésions obstétricales du sphincter de l’anus depuis les recommandations de 2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38219814
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00007-2
Leclercq C
Braund S
Verspyck E
10.1016/j.gofs.2024.01.003
AbstractText Label OBJECTIVES There is a progressive reduction in the rate of episiotomies since the recommendations of the french college of gynaecologists. Our objective was to study the evolution of the rate of episiotomies and Obstetric Anus Sphincter Injury (OASI) since the restriction of episiotomies in our department. /AbstractText AbstractText Label METHODS Observational monocentric retrospective study performed at the Rouen University Hospital. The inclusion criteria were monofetal pregnancies, delivery at a term greater than or equal to 37 weeks of amenorrhea of a living, viable child and by cephalic presentation. We compared two periods corresponding to before and after the 2018 recommendations. We used logistic regression modelling to identify factors associated with the risk of episiotomies and of obstetrical anal injuries, overall and in case of instrumental delivery. /AbstractText AbstractText Label RESULTS We included 3329 patients for the 1st period and 3492 for the 2nd period, and the rate of instrumental deliveries were respectively of 16,4 % (n 547) and 17,9% (n 626). Multivariate analysis showed a significant decrease in the rate of episiotomies in the 2nd period (OR 0,14, IC 95% [0,12 ; 0,16], p 0,0001). Main factors associated with the risk of OASI were primiparity (OR 6,21, IC 95% [3,19 ; 12,11]) and the use of forceps (OR 4,23, IC 95% [2,17 ; 8,27]) overall; and instrumental delivery using forceps (OR 3,25, IC 95% [1,69 ; 6,22]) and delivery during the 2nd period (OR 1,98, IC 95% [1,01 ; 3,88]) in case of instrumental delivery. /AbstractText AbstractText Label CONCLUSIONS Our study confirms that the voluntary reduction in the episiotomy rate does not seem to be associated with an increased risk of OASI, overall and in case of instrumental delivery. However, we show an increase in the rate of OASI in case of instrumental delivery since the latest recommendations. /AbstractText
2
95-101
52
oasi; episiotomy; instrumental delivery; severe perineal tear; vaginal delivery
12
Février
S2468-7189(24)00007-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
étude d'observation
Femelle
enfant
grossesse
humains
épisiotomie
canal anal
études rétrospectives
facteurs de risque
accouchement (procédure)
Complications du travail obstétrical
nouveau-né

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La sénologie à l’ère de la désescalade et de la personnalisation des soins.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38219815
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00010-2
Mathelin C
10.1016/j.gofs.2024.01.006
3
123-124
52
breast cancer; cancer du sein; activité physique; chirurgie; chirurgie axillaire ciblée; lymphoedema; lymphœdème; physical activity; surgery; target axillary dissection
12
Mars
S2468-7189(24)00010-2
publication avant impression
Accès restreint
éditorial

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Nouveautés dans la prise en charge de l’hyperkaliémie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38220492
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00004-3
Lefevre F
Mousseaux C
Bobot M
10.1016/j.revmed.2024.01.004
Hyperkalemia is common in everyday clinical practice, and is a major risk factor for mortality. It mainly affects patients with chronic renal failure (CKD), diabetes or receiving treatment with inhibitors of the renin-angiotensin-aldosterone system (iRAAS). Therapeutic management aims not only to avoid the complications of hyperkalemia, but also to avoid discontinuation of cardio- and nephroprotective treatments such as iRAAS. The use of polystyrene sulfonate, widely prescribed, is often limited by patient acceptability. Recent data have cast doubt on its safety, particularly in terms of digestive tolerance. Two new potassium exchange molecules have appeared on the market: patiromer and zirconium sulfonate. Their value in clinical practice, and their acceptability in the event of prolonged prescription, remain to be demonstrated. The combination of a thiazide diuretic or an inhibitor of the sodium-glucose cotransporter type 2 (iSGLT2) with iRAAS therapy in CKD, may also improve control of kalemia. At present, there are no recommendations for the positioning of the various hypokalemic treatments. The choice of these treatments must be adapted to the patient's pathologies and consider the other expected effects of these molecules.
hyperkalemia; hyperkaliémie; patiromer; polystyrene sulfonate; polystyrène sulfonate; potassium; sodium zirconium cyclosilicate; therapeutics; thérapeutique
13
Janvier
S0248-8663(24)00004-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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François Gros : Une personnalité de premier plan, un homme secret.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38226441
https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.142
https://doi.org/10.5802/crbiol.142
Robert B
10.5802/crbiol.142
I joined François Gros' laboratory in 1975, to study mechanisms of gene expression in eukaryotes. Despite the lack of powerful tools, that would be brought later by genetic engineering, I obtained publishable results and was allowed to defend a third cycle thesis. Thereafter, I joined Margaret Buckingham's group, which was empowering within François' laboratory. I maintained regular meetings with François, a leading figure but a secretive man, who did not readily open up. It was my privilege, over the more than 45 years I have been around him, to have glimpses over what had been really significant to him. This has been a rich and very precious experience.cycle. Après cela, j’ai rejoint le groupe de Margaret Buckingham, qui s’autonomisait dans le laboratoire de François. J’ai continué à avoir des rencontres régulières avec François, personnalité de premier plan mais homme secret, qui ne se livrait pas volontiers. J’ai eu le privilège, au cours des 45 ans et plus où je l’ai côtoyé, d’avoir quelques aperçus de ce qui l’avait marqué, l’avait formé, lui importait vraiment. Ça été une expérience riche et très précieuse.
S2
41-43
346
françois gros; homme secret; personnalité de premier plan; premières expériences de recherche
29
Mars
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Mâle
Récit personnel
article historique

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Les plans d’action écrits pour l’asthme : quel usage en font les pneumologues en France ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38228440
http://www.em-consulte.com/retrieve/pii/S0761-8425(24)00001-9
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00001-9
Soumagne T
Chenivesse C
Didier A
Giovannini-Chami L
Magnan A
Taillé C
et les investigateurs du groupe d’étude PAE
10.1016/j.rmr.2024.01.001
AbstractText Label INTRODUCTION Despite evidence of the benefits of the written asthma action plans (WAP) in asthma control, they remain poorly applied. The aim of our study was to assess the practices of French-speaking pulmonologists and paediatricians in their use of WAP for asthma control and to analyse the contents of several WAPs routinely consulted in treatment of asthma patients. /AbstractText AbstractText Label METHODS Members of three French medical societies (SPLF, G2A, SP2A) were requested to share their WAPs for asthma patients and to participate in an online survey about the possible influence of these documents on their practices. /AbstractText AbstractText Label RESULTS Most (95%) of the 41 WAPs taken into consideration were symptom-based and 34% included peak expiratory flow measurement. All of these action plans were in full compliance with current guidelines. Among the 110 survey respondents, while 65% systematically provided a WAP to their asthma patients, only 30% often or always supplemented the written document with therapeutic education sessions. In almost every case, it was the doctor who presented the WAP to the patient, generally devoting to less than 10minutes to explanation of what they were handing out. /AbstractText AbstractText Label CONCLUSIONS In France, WAPs are generally presented to the patient by the physician, which probably limits the time devoted to explanation of their contents. Furthermore, WAPs are rarely reinforced with therapeutic education. The current study suggests ways of improving the utilization of WAPs in asthma care and treatment. /AbstractText
2
102-109
41
action plan; asthma; asthme; education; plan d’action; éducation
15
Février
S0761-8425(24)00001-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
asthme
asthme
Observance par le patient
autosoins
France

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À propos d’une e-Hypercalcémie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38228453
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00003-1
Guillaud P
Vest P
Billhot M
Doutrelon C
Hejl C
10.1016/j.revmed.2024.01.002
AbstractText Label INTRODUCTION Hypercalcemia is a common biological abnormality. The etiologies are mainly represented by hyperparathyroidism and neoplastic causes. The other causes, including poisoning, are rare, but should not be neglected. /AbstractText AbstractText Label OBSERVATION An 82-year-old female patient presented to the emergency room for repeated falls at home, confusion, drowsiness and digestive symptoms. The initial assessment showed hypercalcemia above 3mmol/L. The etiological exploration revealed a very high concentration of 25OH-vitamin D. After repeated interrogations, it appeared that the cause of this intoxication was the intake of a food supplement purchased on the internet, following a prescription from her dentist. /AbstractText AbstractText Label CONCLUSION Intoxication due to a food supplement containing vitamin D is possible and potentially serious. Raising the awareness of patients and healthcare professionals is necessary in order to prevent this type of poisoning and/or to diagnose it as soon as possible. /AbstractText
3
142-146
45
auto-médication; complément alimentaire; dietary supplements; hypercalcemia; hypercalcémie; hypervitaminose d; hypervitaminosis d; self-medication
15
Mars
S0248-8663(24)00003-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
vitamine D
vitamines
Femelle
humains
sujet âgé de 80 ans ou plus
hypercalcémie
hypercalcémie
compléments alimentaires

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, mais sans diabète, est-ce que le sémaglutide diminue le risque de mortalité cardiovasculaire, d’infarctus du myocarde ou d’AVC comparativement au placebo tout en étant sécuritaire ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38228454
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00007-9
Lanthier L
Langlois MF
Plourde MÉ
Cauchon M
10.1016/j.revmed.2024.01.006
3
178-179
45
15
Mars
S0248-8663(24)00007-9
publication avant impression
Accès restreint
lettre
sémaglutide
hypoglycémiants
peptides glucagon-like
adulte
humains
maladies cardiovasculaires
indice de masse corporelle
infarctus du myocarde
infarctus du myocarde
accident vasculaire cérébral
diabète de type 2
diabète de type 2
hypoglycémiants

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Vaccination ARN messager (ARNm), modèle de transition de la biologie fondamentale à la médecine.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231390
https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.129
https://doi.org/10.5802/crbiol.129
Sansonetti PJ
10.5802/crbiol.129
Sixty years elapsed between the discovery of messenger RNA (mRNA) and the use of this molecule in an unprecedented global vaccination campaign that brought the Covid-19 pandemic under control. Sixty years of doubts for some and certainties for others about the possibility of using mRNA-an example of synthetic biology-in therapeutic medicine and vaccinology. Years of translational research and development have culminated in the success of anti-Covid-19 mRNA vaccines and the promise of more to come against emerging pathogens. A new paradigm in vaccinology, enabling pandemics to be tackled as they emerge. A lesson to be learned: medical progress is less a question of time than of the critical nature of the biological discovery that underpins it. Before leaving us, François Gros, who played a key role in the discovery of mRNA, was able to appreciate the relevance of this obvious fact.Soixante ans ont séparé la découverte de l’ARN messager (ARNm) et l’utilisation de cette molécule dans une campagne planétaire inédite de vaccination ayant permis le contrôle de la pandémie de Covid-19. Soixante ans de doutes chez certains et de certitudes chez d’autres sur la possibilité d’utiliser l’ARNm — un exemple de biologie de synthèse — en médecine thérapeutique et en vaccinologie. Des années de recherche et de développement « translationnels » pour aboutir au succès de vaccins à ARNm anti-Covid-19 et à la promesse d’autres à venir contre de nouveaux pathogènes émergents. Un nouveau paradigme de la vaccinologie permettant d’attaquer les pandémies dans le temps de leur émergence. Une leçon à tirer, le progrès médical est moins affaire de temps que de la nature décisive de la découverte biologique qui le sous-tend. François Gros, acteur de la découverte de l’ARNm a pu, avant de nous quitter, juger de la pertinence de cette évidence.
S2
69-74
346
arnm; biologie synthétique; covid-19; vaccins
29
Mars
publication avant impression
Accès restreint
résumé en anglais
article de périodique
ARN messager
humains
pandémies
ARN messager
vaccination
biologie
article historique

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Pathologie thyroïdienne. Actualités et problèmes pratiques. Introduction.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38233234
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00002-6
Guyétant S
10.1016/j.annpat.2023.12.009
2
90-91
44
16
Mars
S0242-6498(24)00002-6
publication avant impression
Accès restreint
article de périodique

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Une curieuse lésion biphasique du sein.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38233235
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00004-X
Schoelinck J
Heinemann M
Pissaloux D
Franceschi T
Treilleux I
10.1016/j.annpat.2023.12.011
Adenomyoepithelioma represents 0.5% of breast tumors in postmenauposal women. Prognosis is good when the tumor is benign. However, its malignant variant is associated with a poor prognosis with local recurrences and metastatic potential. We present the case of a malignant adenomyoepithelioma, expose the 2019 WHO classification issues and propose a classification in three categories: benign, atypical and malignant adenomyoepitheliomas (in situ and invasive).
adénomyoépithéliome atypique; adénomyoépithéliome malin; atypical adenomyoepithelioma; epithelial/myoepithelial proliferation; malignant adenomyoepithelioma; prolifération épithéliale/myoépithéliale
16
Janvier
S0242-6498(24)00004-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Bethesda 2023: nouvelle terminologie en cytopathologie thyroïdienne.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38233236
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00236-5
Cochand-Priollet B
Vielh P
10.1016/j.annpat.2023.12.008
A third update of The Bethesda System for Reporting Thyroid Cytopathology has been published in 2023 following the first (2010) and second (2017) versions. The main modifications are the following 1) a new co-Editor, 2) 4 associate editors, 3 of them from Europe, 3) the inclusion of 65 co-authors, 19 of them from Europe, 4) 2 new chapters: one dealing with pediatrics thyroid cytopathology and the other one describing molecular cytopathology profiling, 5) updated risks of malignancy (ROM), 6) a terminology in line with the 2022 WHO classification of thyroid tumors, 7) diagnostic categories now defined by a unique name, 8) 2 subtypes in the Atypia of Undetermined Significance category with corresponding ROM.
1
30-35
44
cytopathologie; cytopathologie moléculaire; cytopathology; molecular cytopathology; terminologie; terminology; thyroid; thyroïde
16
Février
S0242-6498(23)00236-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
enfant
cytoponction
tumeurs de la thyroïde
tumeurs de la thyroïde
nodule thyroïdien
nodule thyroïdien
adénocarcinome folliculaire
études rétrospectives

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Intérêt des réunions de concertation pluridisciplinaires dédiées à l’endométriose : à partir d’une série de 682 patientes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38237734
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00009-6
Osada M
Faller E
Lecointre L
Boisrame T
Martel C
Gabriele V
Akladios C
Host A
10.1016/j.gofs.2024.01.005
AbstractText Label OBJECTIVE We decided to conduct a study based on these multidisciplinary team (MDT) in order to investigate their impact at the University Hospitals of Strasbourg and look for ways to improve this MDT. /AbstractText AbstractText Label METHODS This is a retrospective study of the 682 patients presented to endometriosis MDT from its inception in March 2017 to December 2020 Results: The MDT decision was different from that initially proposed by the patient's referent for 406 patients (60%). Surgery was chosen for 417 patients (61%) and assisted reproduction for 261 patients (38%). A review of the MRI by a referring radiologist was carried out for 348 cases (51%), with a modification of the results for 255 patients (73%). Initial underestimation of lesions was noted in 198 cases. /AbstractText AbstractText Label CONCLUSION Our study has shown the importance of MDT in endometriosis, since the therapeutic proposal was modified in 60% of cases. In addition, we supported the importance of radiologists specializing in this field, since they made a modification in two-thirds of the MRIs reread. These results show the importance of collegial discussions, which can modify the decisions of medical teams. This underlines the importance of setting up endometriosis networks. /AbstractText
endométriose; chirurgie; endometriosis; infertility; infertilité; medically assisted procreation; multidisciplinary consultation meeting; procréation médicalement assistée; réunion de concertation pluridisciplinaire; surgery
16
Janvier
S2468-7189(24)00009-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Autogreffe de cellules souches périphériques dans la sclérodermie systémique : un progrès important, mais il faut tempérer notre enthousiasme !
2024
http://www.ncbi.nlm.nih.gov/pubmed/38238136
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00002-X
Mouthon L
10.1016/j.revmed.2024.01.001
Three prospective randomized studies have demonstrated the efficacy of autologous hematopoietic stem cell (HSC) transplantation in systemic sclerosis (SSc) on survival. These results encourage us to offer this therapy to patients who have a rapidly progressive disease and who have early symptoms but no advanced visceral involvement. HSC autograft can thus be discussed in patients with diffuse cutaneous SSc with a duration of the disease since the first visceral manifestations (cutaneous, cardiac, digestive, pulmonary, or renal) excluding Raynaud's phenomenon of less than 5 years. However, the indications for HSC autograft in SSc validated at European level and in the national diagnostic and care protocol (PNDS) are broader and some of these indications are debatable, in particular in patients with worsening diffuse interstitial lung disease. These indications are discussed in a reasoned way, taking into account the level of evidence and the toxicity of the HSC autograft.
2
100-103
45
interstitial lung disease; morbidity; mortality; peripheral stem cell transplantation; systemic scleroderma; autogreffe de cellules souches hématopoïétiques; morbidité; mortalité; pneumopathie interstitielle diffuse; sclérodermie systémique diffuse
17
Février
S0248-8663(24)00002-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
transplantation de cellules souches de sang périphérique
études prospectives
sclérodermie systémique
sclérodermie systémique
transplantation de cellules souches hématopoïétiques
transplantation autologue

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Lumière bleue et implants intraoculaires : croyances et réalités.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38241770
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00575-2
Desmettre T
Baillif S
Mathis T
Gatinel D
Mainster M
10.1016/j.jfo.2023.104043
The first intraocular lenses (IOLs) used for cataract surgery transmitted both ultraviolet (UV) radiation and visible light to the retina. Colorless UV-blocking IOLs were introduced and rapidly adopted in the 1980s. Yellow-tinted blue-blocking (also known as blue-filtering) IOLs were marketed in the early 1990s. Blue-blocking IOLs were intended to simulate age-related crystalline lens yellowing to reduce the cyanopsia that some patients experienced after cataract surgery. When blue-filtering IOLs were introduced in North America, however, blue-blocking chromophores were advocated as a way to protect patients from age-related macular degeneration (AMD) despite the lack of evidence that normal environmental light exposure causes AMD. The blue light hazard is a term that describes the experimental finding that acute, abnormally intense light exposures are potentially more phototoxic to the retina when short rather than long wavelengths are used. Thus, in brief exposures to intense light sources such as welding arcs, ultraviolet radiation is more hazardous than blue light, which is more hazardous than longer wavelength green or red light. International commissions have cautioned that the blue light hazard does not apply to normal indoor or outdoor light exposures. Nonetheless, the hazard is used for commercial purposes to suggest misleadingly that ambient environmental light can cause acute retinal phototoxicity and increase the risk of AMD. Very large epidemiological studies show that blue-blocking IOLs do not reduce the risk or progression of AMD. Additionally, blue-filtering IOLs or spectacles cannot decrease glare disability, because they decrease image and glare illuminance in the same proportion. Blue light is essential for older adults' scotopic photoreception needed to reduce the risk of nighttime falling and related injuries. It is also critical for circadian photoreception that is essential for good health, sleep and cognitive performance. Unfortunately, age-related pupillary miosis, retinal rod and ganglion cell photoreceptor degeneration and decreased outdoor activity all reduce the amount of healthful blue light available to older adults. Blue-restricting IOLs further reduce the available blue light at a time when older adults need it most. Patients and ophthalmologists are exposed to hypothesis-based advertisements for blue-filtering optical devices that suppress short wavelength light critical for vision in dim lighting and for good physical and mental health. Spectacle and intraocular lens selections should be based on scientific fact, not conjecture. Ideal IOLs should improve photoreception rather than limit it permanently. Practice efficiency, surgical convenience and physician-manufacturer relationships may eliminate a patient's opportunity to choose between colorless blue-transmitting IOLs and yellow-tinted, blue-restricting IOLs. Cataract surgeons ultimately determine whether their patients have the opportunity to make an informed choice about their future photoreception.
2
104043
47
age; blue light; cataract; cataracte; chirurgie; cristallin; dégénérescence maculaire liée à l’âge/épidémiologie; lens; light; lumière; macular degeneration/epidemiology; prevention; prévention; surgery; vieillissement; control; contrôle; lumière bleue
18
Février
S0181-5512(23)00575-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
sujet âgé
rayons ultraviolets
lentilles intraoculaires
lumière
dégénérescence maculaire
dégénérescence maculaire
dégénérescence maculaire
troubles de la vision
cataracte

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La version 2022 du Système de Paris : quoi de neuf ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242741
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00003-8
Courtade-Saïdi M
10.1016/j.annpat.2023.12.010
The second version of the Paris System for reporting urine cytology was published in 2022. It follows the first version of 2016, which was very successful and widely adopted by many cytopathologists from different countries. Thus, numerous publications using the Paris System have made possible to refine the criteria as well as discussing the limits. The diagnostic accuracy of urinary cytology is high for detection of high-grade urothelial carcinoma, but not for low-grade carcinoma where there are few cytological abnormalities. So, the chapter individualizing low-grade urothelial neoplasms was deleted; the latter were included in the category negative for high-grade urothelial carcinoma. Indeed, the risk of malignancy is replaced by the risk of high-grade urothelial carcinoma. A new chapter has been devoted to urothelial tumors of the upper tract. Finally, the pitfalls linked to cellular degeneration are discussed for each category. The risk of high-grade malignancy associated with each category will help communication with the clinician and help patient care.
carcinome urothélial; cytologie urinaire; système de paris; the paris system; urinary cytology; urothelial carcinoma
18
Janvier
S0242-6498(24)00003-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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La thérapie cellulaire dans tous ses états.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242769
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00005-5
Dougé A
Caux C
Bay JO
10.1016/j.bulcan.2024.01.001
Immunotherapy strategies have revolutionized the management of a significant number of patients in recent years, whether they are undergoing treatment for hematologic malignancies or solid tumors. This therapeutic class is extensive, ranging from antibodies targeting immune checkpoint molecules to adoptive cell therapy strategies, including bispecific antibodies and anticancer vaccines. All these strategies are currently in active development. Adoptive cell therapy involves the infusion of normal or genetically modified immune cells into a patient with the aim of restoring strong antitumor immunity, primarily associated with the cytotoxicity of T lymphocytes. Currently, there are three major adoptive cell therapy strategies: allogeneic hematopoietic stem cell transplantation, CAR-T cell therapy, and TCR-T cell therapy. The objective of this article is to describe the mechanisms of action of these three strategies as well as their current advantages, limitations and constraints.
2
213-221
111
allo-csh; allo-hsct; car-t cell; cell therapy; cellule car-t; cellule tcr-t; cytotoxic t cell; effet gvl; gvl effect; immunotherapy; immunothérapie; lymphocyte t cytotoxique; tcr-t cell; thérapie cellulaire
18
Février
S0007-4551(24)00005-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
transplantation de cellules souches hématopoïétiques
lymphocytes T
tumeurs hématologiques
immunothérapie adoptive
thérapie cellulaire et tissulaire

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Évaluation d’une pratique d’auto-administration médicamenteuse mise en place dans un service de rééducation.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38244678
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00004-X
Vanhaecke M
Hennion-Coussemacq M
Dervaux B
Accaoui P
Pruvost A
Ferret L
Lehmann L
Verryser F
Hiver Q
10.1016/j.pharma.2024.01.004
AbstractText Label UNLABELLED Objectives : Self-administration consists in the administration of medications by the patient himself during his hospitalization. The order of October 10, 2022 (1) modified the April 6, 2011 regulation to allow and regulate self-administration practices in hospital units. This evolution opens new perspectives for patient autonomy. The objective of this study is, firstly, to evaluate the rate of medication errors from patients under self-administration and secondly, to evaluate the satisfaction of patients and caregivers. /AbstractText AbstractText Label MATERIAL AND METHODS Eligible patients were recruited from a locomotor and polyvalent rehabilitation unit. After verification of eligibility, explanation given to the patient about the hospital self-administration of medication procedure and signature of the compliance agreement, patients started self-administration. Medication errors were reported during seven days. Evaluations of patient and staff satisfaction were also carried out. /AbstractText AbstractText Label RESULTS Of the 83 patients admitted to the care service, 32 were able to experiment self-administered medication procedure during their hospitalization. To assess the safety of this practice, 1235 drug intakes were analyzed. 94 administration errors were noted: 98% of them concerned analgesic drugs. All of these errors were omissions and none of them were rated as serious. The 20 patients questioned were all satisfied with self-administration. The 14 carers interviewed were satisfied with this change in practice. /AbstractText AbstractText Label CONCLUSION The medication self-administration process set up in the rehabilitation unit did not lead to serious medication errors. Patients and caregivers reported being satisfied with this new hospital practice. /AbstractText
2
329-341
82
: self-administration; auto-administration; evaluation des pratiques professionnelles; evaluation of professional practices; rehabilitation; rééducation
18
Mars
S0003-4509(24)00004-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
préparations pharmaceutiques
humains
Erreurs de médication
hospitalisation
hôpitaux

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Comment l’activité physique pourrait-elle réduire le risque de survenue et de récidive des cancers du sein ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38244776
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00008-4
Meneu A
Lavoué V
Guillermet S
Levêque J
Mathelin C
Brousse S
10.1016/j.gofs.2024.01.004
AbstractText Label OBJECTIVES Breast cancer is the most frequent and deadly cancer among women. In France, 50% of adults are currently overweight, mostly as a result of a sedentary lifestyle. Numerous studies have highlighted overweight, obesity and lack of physical activity as risk factors for the occurrence and prognosis of cancers, particularly breast cancer. The aim of this study was to understand the extent to which physical activity can improve this prognosis, and what the pathophysiology is. /AbstractText AbstractText Label METHODS The Senology Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF) based its responses on an analysis of the international literature using a Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA) methodology conducted on the PubMed database between 1994 and 2023. /AbstractText AbstractText Label RESULTS A total of 70 articles were selected, demonstrating the role of regular physical activity in reducing the risk of breast cancer occurrence and recurrence. This role in controlling carcinogenesis is mediated by metabolic factors such as leptin, adiponectin and insulin, sex hormones and inflammation. The signaling pathways deregulated by these molecules are known carcinogenic pathways which could be used as therapeutic targets adapted to this population, without replacing the essential hygienic-dietary recommendations. /AbstractText AbstractText Label CONCLUSION Physical activity has a protective effect on breast cancer risk and prognosis. We must therefore continue to raise awareness in the general population and promote physical activity as a means of primary, secondary, and tertiary prevention. /AbstractText
3
158-164
52
activité physique; breast cancer; cancer du sein; obesity; obésité; physical activity; prevention; prévention; sedentary lifestyle; sédentarité
18
Mars
S2468-7189(24)00008-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
méta-analyse
adulte
humains
Femelle
tumeurs du sein
tumeurs du sein
surpoids
région mammaire
exercice physique
France

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Développement d’un outil d’évaluation de l’anxiété de performance en obstétrique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38246241
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00011-4
Andriamanjay D
Castel P
Ercole C
Bretelle F
Agostini A
Berbis J
Blanc J
10.1016/j.gofs.2024.01.007
AbstractText Label OBJECTIVE Developing a measuring tool for physician's performance anxiety during obstetrical procedures, as a self-administered questionnaire. /AbstractText AbstractText Label METHODS We used the Delphi method. First, we did a literature review to identify the items to submit for the first round. A panel of experts was asked to rate the relevance of items from one to six. For the first round of Delphi, items were retained if more than 70% of respondents assigned a five or six rating. Items were excluded if more than 70% of respondents assigned a one or two rating. All the other items, plus those suggested by the panel, were submitted to a second round of Delphi. The same item selection conditions were applied to the second round. /AbstractText AbstractText Label RESULTS The overall response rate to the Delphi was 79% (19 respondents). At the end of the first round, 14 items were consensually relevant, no item was consensually irrelevant. For the second round, the 18 items that did not find consensus and seven new items suggested by the experts in the first round were submitted. At the end of the second round, nine items were retained by consensus as relevant. /AbstractText AbstractText Label CONCLUSION This study defined by consensus 23 items for a self-questionnaire to measure specific performance anxiety in obstetrics divided into five dimensions: perceived stress, assessment of the risk of complications, medico-legal risk, impact of the healthcare team and peers, self-confidence and decision-making confidence. We intend to validate this tool in real population. /AbstractText
delphi technique; obstetrics; performance anxiety
19
Janvier
S2468-7189(24)00011-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Mésusage du paracétamol en soins primaires : étude transversale dans un contexte rural français.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38246801
Kinouani S
Vielle C
Lambert C
Dupouy J
Laporte C
10.1016/j.therap.2023.11.005
AbstractText Label OBJECTIVE To estimate the prevalence of the paracetamol use for a reason other than pain (qualitative misuse) during the last 12 months in patients consulting their general practitioner, as well as the reasons for this misuse. /AbstractText AbstractText Label METHODS Descriptive cross-sectional analysis, with gender weighting to estimate the prevalence of paracetamol misuse. /AbstractText AbstractText Label RESULTS In total, data from 209 patients were included in the analysis. Among them, 11 patients declared having taken paracetamol for a reason other than pain, i.e., a gender-weighted prevalence of 5.7% (95% CI: 3.0 to 10.4). Nearly two-thirds of these patients said they had done it to feel better. /AbstractText AbstractText Label CONCLUSIONS The paracetamol misuse is rare but real in general practice. Further studies are needed to better understand it, especially qualitative studies. /AbstractText
cross-sectional study; misuse; mésusage; paracetamol; paracétamol; primary care; soins primaires; étude transversale
29
Novembre
S0040-5957(23)00188-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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L’antibiorésistance : un bon exemple du concept « une seule santé ».
2024
http://www.ncbi.nlm.nih.gov/pubmed/38259232
Jarlier V
10.5802/crbiol.139
Antibiotic resistance is the direct deleterious consequence of two synergistic causes linked to human activity: the massive use of antibiotics in human and animal health, which leads to the selection of the most resistant bacteria, and the spread of these selected resistant bacteria, directly by cross-transmission within human and animal populations and indirectly via the environment. The one health concept enables an integrated approach of the various components of the issue, linking human, animal and environmental ecosystems and their dynamics.La résistance aux antibiotiques est la conséquence délétère directe de deux causes synergiques liées à l’activité humaine : l’utilisation massive d’antibiotiques en santé humaine et animale, qui entraîne la sélection des bactéries les plus résistantes, et la dissémination des bactéries résistantes ainsi sélectionnées, directement par transmission au sein des populations humaines et animales (« transmission croisée »), et indirectement via l’environnement. Le concept « une seule santé » permet une approche intégrée des différentes composantes de la question, en permettant de relier les écosystèmes humains, animaux et environnementaux et leurs dynamiques.
antibiotiques; bactéries résistantes aux antibiotiques; une seule santé
23
Janvier
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Ventricular septal defect complicating anterior acute myocardial infarction : A Case of transcatheter closure.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38262253
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00153-1
Lamine H
Farhati A
Bouzidi H
Saidane S
Zairi I
Mzoughi K
Kraeim S
10.1016/j.ancard.2023.101718
AbstractText Label INTRODUCTION Post-infarction ventricular septal defect (PIVSD) is one of the most serious mechanical complications of acute myocardial infarction (AMI). Over the last decade, percutaneous closure is increasingly undertaken, with results similar to cardiac surgery. We present a case of ST-elevated anterior AMI, complicated by apical PIVSD successfully treated with transcatheter closure. /AbstractText AbstractText Label CASE REPORT An 83-year-old man was hospitalized for chest pain occurred 18 hours before, during the night time. He was an active smoker. Clinical examination revealed normal heart sounds and pulmonary bibasilar crackles. ST-segment elevation with deep T waves inversion in anterior leads were detected on the electrocardiogram. A mildly-reduced ejection fraction (40%) was found by transthoracic echocardiogram. The patient underwent emergency coronary angiography, which revealed a subocclusive stenosis of the mid left anterior descending artery with a TIMI 2 flow, treated by balloon angioplasty and drug-eluting stent. Four days after revascularization, the patient developed an acute deterioration with signs of decompensated heart failure and a new holosystolic murmur with large irradiation. Inotropic agents' administration was required to maintain a precarious hemodynamic condition. A bedside Echo revealed an apical VSD, measuring 15 10 mm, with left-to-right shunting, and pulmonary hypertension. The patient was scheduled for transcatheter PIVSD closure. The procedure was performed under fluoroscopic guide. Two vascular access sites were placed, femoral arterial and right internal jugular vein. Through the right internal jugular vein, a 24-mm Amplatzer atrial septal occluder on a 9 French Amplatzer TREVISIO intravascular delivery system was advanced via right ventricle into the PIVSD. Contrast fluoroscopy was used to assess apposition and the degree of shunt reduction before release. Echocardiographic evaluation performed 48 hours later confirmed a correct apposition of the device with insignificant residual shunt. At 6 months follow-up, he was asymptomatic, with unchanged prosthetic findings. /AbstractText AbstractText Label CONCLUSION Percutaneous closure has been emerged as a valid cost-effective alternative to surgery and should be advised. However, debate remains on the optimal preprocedural optimization, timing of repair and modality of treatment. /AbstractText
2
101718
73
communication interventriculaire; fermeture percutanée; infarctus du myocarde; myocardial infarction; percutaneous closure; ventricular septal defect
22
Avril
S0003-3928(23)00153-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
Mâle
humains
sujet âgé de 80 ans ou plus
résultat thérapeutique
endoprothèses à élution de substances
cathétérisme cardiaque
infarctus du myocarde
procédures de chirurgie cardiaque
dispositif d'occlusion septale
infarctus du myocarde antérieur
communications interventriculaires
communications interventriculaires
communications interventriculaires

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Cas clinique : cas rare d'un faux anévrisme spontané de l'artère fémorale superficielle révélant une maladie de Behçet chez un jeune patient.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38262254
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00142-7
Kejiou H
Rizziki A
Ouhmich M
Benzirare A
Mahi OE
10.1016/j.ancard.2023.101707
Behçet's disease is a chronic inflammatory vascular disorder that can affect arteries and veins of various sizes. Arterial involvement, which plays a significant prognostic role, requires a treatment approach involving corticosteroids, immunosuppressants, and potentially surgical or endovascular procedures. This article presents the case of a young man diagnosed with Behçet's disease, manifested by a spontaneous pseudoaneurysm in the superficial femoral artery. The patient underwent surgical intervention to remove the pseudoaneurysm and restore circulation using a venous graft. This case underscores the importance of considering Behçet's disease in vascular manifestations.
2
101707
73
artère fémorale superficielle; behçet's disease; faux anévrisme; griffon veineuse; maladie de behçet; pseudoaneurysm; superficial femoral artery; venous graft
22
Avril
S0003-3928(23)00142-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
Mâle
humains
faux anévrisme
faux anévrisme
faux anévrisme
maladie de Behçet
maladie de Behçet
artère fémorale
pronostic
procédures endovasculaires

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Une cause rare de syndrome coronarien aigu : l'embolie paradoxale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38262255
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00156-7
Boussaadani BE
Mayoussi S
Zergoune N
Hara L
Amine EC
Raissouni Z
10.1016/j.ancard.2023.101721
Coronary artery embolism is an uncommon cause of myocardial infarction (MI). Among several etiologies of coronary embolism, we mention a very rare cause which is the paradoxical embolism via patent foramen ovale (PFO). It interests generally youngest people without cardiac risk factors. We report three cases who presented ST-elevation MI (STEMI) due to paradoxical embolism with high risk PFO that can justify embolic infarction. The aim of this article is to define the high risk PFO, to establish causal link between PFO and embolic events and to guide therapeutic management.
2
101721
73
coronary artery embolism; embolie de l'artère coronaire; embolie paradoxale; fop et événements emboliques; pfo and embolic events; paradoxical embolism
22
Avril
S0003-3928(23)00156-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
embolie paradoxale
syndrome coronarien aigu
foramen ovale perméable
embolie
infarctus du myocarde

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Association d’un myxome de l’oreillette gauche et d’un rétrécissement mitral : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38266406
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00154-3
Bennani G
Atlas I
Zahri S
Haboub M
Drighil A
Habbal R
10.1016/j.ancard.2023.101719
Atrial myxoma is a rare and benign clinical entity. It remains common in women and mainly affects the left atrium. Its clinical picture is polymorphic. We report the case of a 53-year-old woman who consulted for dyspnea with cardiac failure's picture. The diagnosis of myxoma of the left atrium was made on echocardiography which also objectified the existence of mitral stenosis. The patient underwent surgical excision and mitral valve replacement with good postoperative outcomes.
2
101719
73
cardiac failure; insuffisance cardiaque; left atrium; mitral stenosis; myxoma; myxome; oreillette gauche; sténose mitrale
23
Avril
S0003-3928(23)00154-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
humains
Femelle
adulte d'âge moyen
sténose mitrale
sténose mitrale
sténose mitrale
atrium du coeur
atrium du coeur
échocardiographie
tumeurs du coeur
tumeurs du coeur
tumeurs du coeur
myxome
myxome

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Facteurs de risque de lésions malpighiennes intra-épithéliale de haut grade ou de cancer du col de l’utérus en cas de Maladie Inflammatoire Chronique de l’Intestin.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38266774
Dujardin C
Balcaen T
Vanoost A
Chatelain D
Gondry J
Fumery M
Foulon A
10.1016/j.gofs.2024.01.008
AbstractText Label INTRODUCTION Chronic inflammatory bowel disease (IBD) is thought to increase the risk of high-grade histological intraepithelial lesions (HGIL) and cervical cancer. The risk factors for developing these lesions are poorly understood. /AbstractText AbstractText Label MATERIALS AND METHODS This is a single-center retrospective case-control study including IBD patients followed at our University Hospital Center from 2011 to 2021 who presented with HGIL or cervical cancer. Four controls were case-matched according to IBD type, age, active smoking and multiparity. /AbstractText AbstractText Label RESULTS Eighteen cases and 72 controls were included. We found no significant differences between the 2 groups with regard to mean age at IBD diagnosis, mean duration of IBD, IBD location, history of IBD-related surgery or even association with another chronic inflammatory disease. In our study, the use of immunosuppressants/biotherapies in these patients (50% (9/18) for cases vs. 56% (40/72) for controls; p 0.9) was not a risk factor for IGRA or cervical cancer. Similarly, neither the total duration of exposure to immunosuppressants/biotherapies (9, 9 8 years for cases vs. 6, 6 5.3 years for controls; p 0.1), nor combined therapies (11% (2/18) for cases vs. 6% (4/72) for controls; p 0.3), nor azathioprine or methotrexate use (22% (4/18) for cases vs. 11% (8/72) for controls; p 0.3) were found to be risk factors. /AbstractText AbstractText Label CONCLUSION In our study, we found no risk factors for patients with IBD to develop IGRA or cervical cancer. /AbstractText
22
Janvier
S2468-7189(24)00012-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Les pièges de l’analyse dichotomique d’une variable biologique continue: l’exemple de la taille maternelle et du pronostic de l’accouchement d’un enfant de plus de 4,0kg.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38266775
Boujenah J
Wahnich A
Korb D
10.1016/j.gofs.2024.01.009
22
Janvier
S2468-7189(24)00013-8
publication avant impression
Accès restreint
lettre

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Suspicion d’anomalie constitutionnelle au diagnostic de leucémie chez l’enfant : mise au point du comité leucémies de la Société française des cancers de l’enfant.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267311
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00004-3
Strullu M
Cousin E
de Montgolfier S
Fenwarth L
Gachard N
Arnoux I
Duployez N
Girard S
Guilmatre A
Lafage M
Loosveld M
Petit A
Perrin L
Vial Y
Saultier P
10.1016/j.bulcan.2023.11.011
The spectrum of childhood leukemia predisposition syndromes has grown significantly over last decades. These predisposition syndromes mainly involve CEBPA, ETV6, GATA2, IKZF1, PAX5, RUNX1, SAMD9/SAMD9L, TP53, RAS-MAPK pathway, DNA mismatch repair system genes, genes associated with Fanconi anemia, and trisomy 21. The clinico-biological features leading to the suspicion of a leukemia predisposition are highly heterogeneous and require varied exploration strategies. The study of the initial characteristics of childhood leukemias includes high-throughput sequencing techniques, which have increased the frequency of situations where a leukemia predisposing syndrome is suspected. Identification of a leukemia predisposition syndrome can have a major impact on the choice of chemotherapy, the indication for hematopoietic stem cell transplantation, and screening for associated malformations and pathologies. The diagnosis of a predisposition syndrome can also lead to the exploration of family members and genetic counseling. Diagnosis and management should be based on dedicated and multidisciplinary care networks.
3
291-309
111
childhood leukemia; leucémie de l’enfant; myelodysplastic syndrome; pre-leukemic state; predisposition; prédisposition; syndrome myélodysplasique; état préleucémique
23
Mars
S0007-4551(24)00004-3
publication avant impression
Accès restreint
résumé en anglais
guide de bonnes pratiques
Protéine SAMD9, humain
protéines et peptides de signalisation intracellulaire
enfant
humains
tumeurs
leucémies
leucémies
leucémies
famille
syndrome de Down
prédisposition génétique à une maladie

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Réaction paradoxale tuberculeuse.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267320
Azoulay LD
Houist AL
Feredj E
Vindrios W
Gallien S
10.1016/j.revmed.2024.01.008
Paradoxical tuberculosis reaction is defined as the aggravation of lesions present at diagnosis or the development of new lesions under anti-tuberculosis treatment, after exclusion of other alternate causes. It affects 5 to 30% of tuberculosis patients, with a variable prevalence depending on the site of infection and the clinical background. The diagnosis of paradoxical reaction is one of elimination, and requires having ruled out therapeutic failure, notably linked to poor compliance and/or to the presence of mycobacterial antibiotic resistance. The severity of paradoxical tuberculosis reaction lies in its neurological impairment. Despite its clinical importance, the mechanisms involved remain poorly understood and its management is not consensual. Corticosteroids are the cornerstone in the medical management. The role of anti-TNF agents, currently proposed in cases of corticodependence or corticoresistance, remains to be properly defined.
anti-tnf; corticosteroid; corticoïdes; granulomatose; granulomatosis; immune reconstitution inflammatory syndrome; paradoxical reaction; réaction paradoxale; syndrome inflammatoire de reconstitution immune; tuberculose; tuberculosis
23
Janvier
S0248-8663(24)00028-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

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Soins palliatifs : il est temps de clarifier le champ lexical.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267321
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00029-8
Robert R
Goldberg M
10.1016/j.revmed.2024.01.009
2
61-64
45
end-of-life; fin de vie; limitation arrêt thérapeutique; palliative care; quality of life; qualité de vie; semantic; soins palliatifs; sémantique; withholding withdrawing life support
23
Février
S0248-8663(24)00029-8
publication avant impression
Accès restreint
article de périodique
humains
soins palliatifs
soins terminaux

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Argumentaire « en faveur » de la greffe de cellules souches hématopoïétiques autologues dans la sclérodermie systémique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267322
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00006-7
Pugnet G
10.1016/j.revmed.2024.01.003
Autologous haematopoietic stem cell transplantation for systemic scleroderma, developed over more than 25 years, has shown in three randomised controlled clinical trials a significant impact not only in event-free survival, overall survival, cutaneous and pulmonary involvement, but also in the quality of life of patients living with recent severe diffuse cutaneous systemic scleroderma, compared with IV cyclophosphamid despite a transplant-related mortality between 2.4 and 10%. No immunosuppressants or biologics have shown such an impact on mortality in this disease. The risk of relapse is estimated between 9 and 24%, two years after transplant. On the basis of these results, French and international guidelines now position autologous haematopoietic stem cell transplantation as a level 1A evidence-based therapeutic alternative in severe early and rapidly progressive systemic scleroderma.
2
104-108
45
autogreffe; autologous haematopoietic stem cell transplantation; cell therapy; sclérodermie systémique; systemic scleroderma; thérapie cellulaire
23
Février
S0248-8663(24)00006-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
cyclophosphamide
immunosuppresseurs
humains
qualité de vie
transplantation de cellules souches hématopoïétiques
cyclophosphamide
immunosuppresseurs
transplantation autologue
sclérodermie systémique

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Mise en place du dépistage de l’infection congénitale à cytomégalovirus dans une maternité française de type 3.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38272182
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00014-X
Mazeau PC
Hamon M
Ribot É
Hantz S
Alain S
10.1016/j.gofs.2024.01.010
AbstractText Label OBJECTIVES Congenital cytomegalovirus (CMV) infection is the most common congenital infection and the leading cause of infectious neurosensorial disability in newborns. We wanted to organize the management of women from the beginning of pregnancy allowing access to antenatal treatment with valaciclovir, recognized since 2020 as limiting materno-fetal transmission. To this end, we set up and evaluated the interest of systematic screening for CMV infection in our maternity. We wanted to organize care for women from the very start of pregnancy. /AbstractText AbstractText Label METHODS retrospective and comparative descriptive study carried out at the CHRU de Limoges from July 2017 to December 2019 (targeted screening), then from January 2020 to June 2022, during which period we implemented systematized screening by iterative serologies at the 3rd, 6th, 8th months and before delivery. Our main evaluation criteria were the seroprevalence of CMV infection and the rate of congenital infection. We then described our cases of infection (primary or secondary) during pregnancy. /AbstractText AbstractText Label RESULTS CMV seroprevalence in our pregnant women increased significantly from 52.7% (779/1478 women screened) to 58.4% (3852/6599 women screened) between the 2 study periods (p 0.04). We diagnosed 11 infections during the first part of the study vs. 27 during the second, with a significant increase in primary infections from 0.14% (9/6524 births) to 0.37% (24/6426 births) (p 0.008). Only 3 secondary infections were diagnosed during the second study period. The rate of congenital infections remained stable between the 2 study periods (6 children/6524 0.09% vs. 8 children/6426 0.12%; p 0.57). /AbstractText AbstractText Label CONCLUSION Our results confirmed the interest of screening for CMV infection, while modifying the screening strategy we had initiated. /AbstractText
congenital infection; cytomegalovirus; pregnancy; screening
23
Janvier
S2468-7189(24)00014-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Carcinome à cellules hautes et à polarité inversée du sein : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38272722
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00001-4
Hmidi A
Houcine Y
Kamoun S
Ilhem B
Goucha A
Driss M
10.1016/j.annpat.2024.01.001
Reverse polarity high-cell carcinoma of the breast, formerly known as reverse polarity solid papillary carcinoma, is a rare entity recently introduced into the latest edition of the WHO classification of breast tumors. Its phenotype is triple-negative, and its diagnosis difficult. Although few cases have been reported in the literature, knowledge of this breast tumor is essential to distinguish it from other triple-negative carcinomas, which have a poorer prognosis. We report a case of high-cell, inverted-polarity carcinoma of the breast in a 43-year-old female patient with no history of breast neoplasia and no palpable mass on clinical examination. The tumour was discovered following a screening echomammogram, which revealed a lesion classified ACR 4b. A microbiopsy of this lesion concluded that it was a papillary proliferation that should be removed. A lumpectomy was performed. Histopathological and immunohistochemical studies of the surgical specimen confirmed the diagnosis of high-cell, reverse-polarity carcinoma expressing calretinin and IDH1. Given the rarity of this entity, there is no standard treatment. In our case, a mastectomy without lymph node curage was performed. The extension work-up was negative and the patient received no adjuvant treatment. After 12 months, the patient is in complete remission. In this case report, we describe the histopathological, immunohistochemical and molecular features of this rare entity.
breast cancer; cancer du sein; carcinome à cellules hautes et à polarité inversée; case report; high-cell and reverse polarity carcinoma; lésion papillaire; papillary lesion; rapport de cas; rare
24
Janvier
S0242-6498(24)00001-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Complications pulmonaires de la granulomatose septique chronique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38272769
http://www.em-consulte.com/retrieve/pii/S0761-8425(24)00002-0
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00002-0
Salvator H
Mahlaoui N
Suarez F
Marcais A
Longchampt E
Tcherakian C
Givel C
Chabrol A
Caradec E
Lortholary O
Lanternier F
Goyard C
Couderc LJ
Catherinot E
10.1016/j.rmr.2024.01.002
Chronic Granulomatosis Disease (CGD) is an inherited immune deficiency due to a mutation in the genes coding for the subunits of the NADPH oxidase enzyme that affects the oxidative capacity of phagocytic cells. It is characterized by increased susceptibility to bacterial and fungal infections, particularly Aspergillus, as well as complications associated with hyperinflammation and granulomatous tissue infiltration. There exist two types of frequently encountered pulmonary manifestations: (1) due to their being initially pauci-symptomatic, possibly life-threatening infectious complications are often discovered at a late stage. Though their incidence has decreased through systematic anti-bacterial and anti-fungal prophylaxis, they remain a major cause of morbidity and mortality; (2) inflammatory complications consist in persistent granulomatous mass or interstitial pneumoniae, eventually requiring immunosuppressive treatment. Pulmonary complications recurring since infancy generate parenchymal and bronchial sequelae that impact functional prognosis. Hematopoietic stem cell allograft is a curative treatment; it is arguably life-sustaining and may limit the morbidity of the disease. As a result of improved pediatric management, life expectancy has increased dramatically. That said, new challenges have appeared with regard to adults: difficulties of compliance, increased inflammatory manifestations, acquired resistance to anti-infectious therapies. These different developments underscore the importance of the transition period and the need for multidisciplinary management.
2
156-170
41
aspergillus; chronic granulomatous disease; déficit immunitaire héréditaire; granulomatose septique chronique; inflammation; nadph oxidase; nadph oxydase; primary immunodeficiency
24
Février
S0761-8425(24)00002-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
NADPH oxidase
adulte
humains
enfant
granulomatose septique chronique
granulomatose septique chronique
granulomatose septique chronique
NADPH oxidase
NADPH oxidase
bactéries
poumon
mutation

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François Gros, secrétaire perpétuel de l’Académie des sciences.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38275107
https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.144
https://doi.org/10.5802/crbiol.144
Bach JF
10.5802/crbiol.144
François Gros was Permanent Secretary of the French Academy of Sciences from 1991 to 2000. His immense scientific knowledge, his tireless efforts to develop international relations, particularly with developing countries, and his exceptional personality have greatly contributed to the modernisation and influence of the Academy.François Gros a été secrétaire perpétuel de l’Académie des sciences de 1991 à 2000. Son immense culture scientifique, son activité incessante pour le développement des relations internationales en particulier vers les pays en développement, et sa personnalité exceptionnelle ont grandement contribué à la modernisation et au rayonnement de l’Académie.
S2
91-93
346
académie des sciences; françois gros; secrétaire perpétuel
29
Mars
publication avant impression
Accès restreint
résumé en anglais
article de périodique
académies et instituts
France
article historique

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Caractéristiques et pronostic des insuffisances rénales aiguës dialysées au cours des vascularites à ANCA.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38282439
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ndt.2024.58
Siham A
Hafedh F
Jean-Jacques B
Pierre-Antoine M
10.1684/ndt.2024.58
Renal involvement in ANCA (Anti Neutrophil Cytoplasmic Antigen) vasculitis is common and is associated with increased mortality with a significant risk of progression to end-stage renal disease. The aim of this study is to investigate the epidemiological, clinicopathological, therapeutic and evolutionary characteristics of patients with ANCA vasculitis with acute renal injury, and to evaluate the impact of haemodialysis in the acute phase on mortality and renal recovery. Secondary objectives are to investigate other risk factors that impact on overall and renal survival. 31 patients were included ; the mean follow-up time was 30 months. The mean age was 68.52 years, and the sex ratio 0.72. All patients had acute renal failure, with histology revealing a mixed form in 45% of cases and a sclerotic form in 12.9% of cases. Pulmonary involvement was found in 58% of cases. 71% of patients had ANCA with anti-myeloperoxydase specificity, and 25.8% anti-proteinase 3 specificity. 32.2% of patients required haemodialysis, of which 60% were weaned. As initial treatment, 58.1% of patients received cyclophosphamide and 35.5% rituximab. The relapse rate was 6.5%. Infectious and cardiovascular complications affected more than half of the patients. The mortality rate was 19.35%. Comparing the two groups of patients dialysed in the acute phase and not dialysed, it appears that the overall and renal mortality was comparable. The progression to end-stage renal failure was higher in the dialysis patients. In a multivariate study, the presence of chronic kidney disease in the history and pulmonary involvement were associated with higher mortality.L’atteinte rénale au cours des vascularites à ANCA (anticorps anticytoplasmes des polynucléaires neutrophiles) est fréquente ; elle est associée à une surmortalité avec un risque important d’évolution vers l’insuffisance rénale terminale. L’objectif de ce travail est d’étudier les caractéristiques épidémiologiques, clinico-paracliniques, thérapeutiques et évolutives de patients atteints de vascularite à ANCA avec insuffisance rénale aiguë, et d’évaluer l’impact du recours à l’hémodialyse à la phase aiguë sur la mortalité et la récupération rénale. Les objectifs secondaires sont de rechercher d’autres facteurs de risque ayant un impact sur la survie globale et rénale. Trente et un patients ont été inclus, avec un délai moyen de suivi de 30 mois. L’âge moyen était de 68,5 ans, et le sex ratio de 0,72. Tous les patients avaient une insuffisance rénale aiguë, dont l’histologie a révélé une forme mixte dans 45 % des cas et une forme scléreuse dans 12,9 % des cas. Une atteinte pulmonaire était retrouvée dans 58 % des cas. Parmi les patients, 71 % (22) avaient des ANCA de spécificité anti-myélopéroxydase, contre 25,8 % (8) de spécificité anti-protéinase 3. Au total, 32,2 % des patients ont eu recours à l’hémodialyse, dont 60 % ont été sevrés. En traitement d’attaque, 58,1 % des patients ont reçu du cyclophosphamide et 35,5 % du rituximab. Le taux de rechutes était de 6,5 %. Les complications infectieuses et cardiovasculaires concernaient plus de la moitié des patients. Le taux de mortalité était de 19,35 %. En comparant les deux groupes des patients dialysés à la phase aiguë et non dialysés, il apparaît que la mortalité globale et rénale était comparable. L’évolution vers l’insuffisance rénale terminale était plus élevée chez les patients dialysés. En étude multivariée, la présence d’une insuffisance rénale chronique dans les antécédents et l’atteinte pulmonaire étaient associées à une surmortalité.
1
1-12
20
acute kidney injury; anca; hemodialyse; mortality; kidney survival; vascularitis
28
Février
publication avant impression
Accès restreint
article de périodique
Anticorps anti-cytoplasme des polynucléaires neutrophiles
humains
sujet âgé
dialyse rénale
Anticorps anti-cytoplasme des polynucléaires neutrophiles
Vascularites associées aux anticorps anti-cytoplasme des neutrophiles
études rétrospectives
défaillance rénale chronique
défaillance rénale chronique
pronostic
atteinte rénale aigüe
atteinte rénale aigüe
atteinte rénale aigüe

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Amélioration de l’accès préemptif à la liste d’attente de transplantation rénale entre 2017 et 2021 : bilan d’un programme régional en Aquitaine.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38287662
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ndt.2024.64
Mathilde PR
Karine M
Frederic J
Eric A
Grégoire R
Jean-Christophe B
Savva A
Cécile D
Noëlle B
Arlette C
Brigitte B
Benjamin D
Olivier D
Xabina L
Hannah K
Karen L
Pierre M
Lionel C
10.1684/ndt.2024.64
AbstractText Label INTRODUCTION Pre-emptive access to the kidney transplant (KT) waiting list remains limited in France, with only 3.9% of patients on pre-emptive KT and 5.6% of patients registered at the time of initiation of dialysis. A similar trend was observed in Aquitaine. The aim of this study was to assess the impact of a regional program in terms of access to the waiting list for patients initiating a kidney replacement therapy (KRT). /AbstractText AbstractText Label METHODS We included all patients assessed for registration on the list between 2017 and 2020, 2017 being the reference year and 2018 the beginning of the program. Using the CRISTAL and REIN registries, we assessed changes in the number of patients on the list at the time of initiation of dialysis or transplantation. /AbstractText AbstractText Label RESULTS The number of new assessed candidates increased gradually each year from 255 in 2017 to 352 in 2020 ( 38%). The number of patients on the list sharply increased in 2018 from 229 in 2017 to 319 in 2018 ( 39.3%) and then remained stable. At the initiation of KRT, the proportion of patients registered on the waiting list increased gradually from 7.1% in 2017 to 18.2% in 2020. The proportion of pre-emptive KT remained stable between 2017 and 2021 (around 7%) with a decrease in 2020 (4.6%). Approximately 60% of patients had a contraindication to transplantation throughout the study. /AbstractText AbstractText Label CONCLUSION This study showed that a regional program aimed at providing better information to healthcare professionals and patients and encouraging rapid assessment of transplant candidates could increase the rate of pre-emptive registration on the KT waiting list for eligible patients over 4 years. /AbstractText AbstractText Label INTRODUCTION L’accès préemptif à la liste d’attente de transplantation rénale (TR) reste limité en France, avec seulement 3,9 % de TR préemptives et 5,6 % de patients inscrits lors de l’initiation de la dialyse. Une tendance similaire était observée en Aquitaine. L’objectif de cette étude était d’évaluer l’impact d’un programme régional en termes d’accès à la liste d’attente chez les patients débutant un traitement de suppléance. /AbstractText AbstractText Label MÉTHODES Nous avons inclus l’ensemble des patients évalués pour une inscription sur liste entre 2017 et 2020, 2017 étant l’année de référence et 2018 l’année de début du programme régional. Nous avons évalué de façon annuelle, grâce aux registres CRISTAL et REIN, l’évolution du nombre de patients inscrits sur liste lors de l’initiation du traitement de suppléance par dialyse ou transplantation. /AbstractText AbstractText Label RÉSULTATS Le nombre de nouveaux candidats évalués a augmenté graduellement chaque année, passant de 255 en 2017 à 352 en 2020 ( 38 %). Le nombre de patients inscrits sur la liste a fortement augmenté en 2018 passant de 229 en 2017 à 319 en 2018 ( 39,3 %), puis est resté stable. À l’initiation du traitement de suppléance, la proportion de patients inscrits a augmenté graduellement passant de 7,1 % en 2017 à 18,2 % en 2020. La proportion de TR préemptive est restée stable entre 2017 et 2021 (environ 7 %) avec une baisse en 2020 (4,6 %). Environ 60 % des patients présentaient une contre-indication à la transplantation tout au long de cette étude. /AbstractText AbstractText Label CONCLUSION Cette étude a montré qu’un programme régional visant à mieux informer les professionnels de santé et les patients et favorisant l’évaluation rapide des candidats à la greffe permet d’augmenter en 4 ans le taux d’inscription préemptive sur liste d’attente de TR chez les patients éligibles. /AbstractText
1
1-10
20
chronic kidney disease; epidemiology; kidney transplant waiting list; kidney transplantation; renal replacement therapy
30
Janvier
publication avant impression
Accès restreint
article de périodique

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Que retenir des états généraux de la médecine interne française ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38290857
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00030-4
Sève P
Morlat P
Ranque B
Lavigne C
Bourgarit A
Rauzy O
Godeau B
Mouthon L
10.1016/j.revmed.2024.01.010
Internal medicine is a medical specialty that is often poorly understood by the general public and sometimes misidentified. In an era of increasing subspecialization and high technicality, it is characterized by a comprehensive approach centered on clinical evaluation. Unlike what is observed in most developed countries, where systemic autoimmune diseases are managed by organ specialists based on their mode of presentation, French internists are at the forefront for diagnosing and managing these diseases. Their multidisciplinary training gives them legitimacy to justify this role. Internists also play a crucial role in the management of patients requiring unplanned hospitalizations downstream from emergency departments and in connection with primary care. Internists primarily practice in a hospital setting, with a specific position in the French healthcare system aligned with the training frameworks of all medical specialties. To better define internal medicine, its role in care activities, as well as in education and research, internists organized a General Assembly of internal medicine that took place on September 28, 2023, in Paris. Structured around think tanks focusing on care, education, and research activities, the general assembly aimed to improve visibility on internal medicine and internists. This article recounts the discussions that animated this meeting and highlights the main ideas that emerged. These general assemblies constitute a foundational step and will be followed by a Consultation Conference in order to better identify and promote internal medicine and internists, regardless of their types and places of practice.
2
69-78
45
comprehensive care; estates general; exercice hospitalier; hospital practice; internal medicine; maladies auto-immunes systémiques; médecine interne; prise en charge globale; speciality; spécialité; systemic autoimmune diseases; états généraux
29
Février
S0248-8663(24)00030-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
médecine interne
prestations des soins de santé
Paris

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Accès géographique à l’hémodialyse : une analyse sur les choix des patients.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38294262
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ndt.2024.59
Devictor B
Crémades A
Izaaryene G
Mazoue F
Brunet P
Gentile S
10.1684/ndt.2024.59
AbstractText Label INTRODUCTION Patients do not always go to the facility closest to their home. /AbstractText AbstractText Label DESCRIPTION A study was carried out in Provence-Alpes Côtes d'Azur (PACA) on patients' preferences to mobilize the hemodialysis offer. /AbstractText AbstractText Label METHODS The data were extracted from the REIN Registry. Potential access was compared with actual access. A survey was carried out among a sample of patients travelling an additional distance of more than 25 km. /AbstractText AbstractText Label RESULTS About a quarter of the patients did not travel to the nearest facility. Of these, 16.3% travelled an additional distance of over 25 km. Patients' choices were determined by the relationship of trust with the team that first set up dialysis, followed by their desire to be followed in a multi-purpose facility. /AbstractText AbstractText Label DISCUSSION While distance remained the decisive factor, human factors were cited in the majority of cases to explain the bypass. /AbstractText AbstractText Label CONCLUSION The links between the first team and the next one should be strengthened. /AbstractText AbstractText Label INTRODUCTION Les patients ne se rendent pas toujours dans l’établissement le plus proche de leur domicile. /AbstractText AbstractText Label DESCRIPTION Une étude a été réalisée en Provence-Alpes Côtes d’Azur (PACA) sur les préférences des patients à mobiliser l’offre d’hémodialyse. /AbstractText AbstractText Label MÉTHODES Les données ont été extraites du Registre REIN. L’accès potentiel a été comparé à l’accès réalisé. Une enquête a été effectuée auprès d’un échantillon de patients parcourant une distance supplémentaire supérieure à 25 km. /AbstractText AbstractText Label RÉSULTATS Environ un quart des patients ne se rendait pas dans la structure la plus proche. Parmi eux, 16,3 % parcouraient un trajet supplémentaire supérieur à 25 km. Les choix des patients étaient déterminés par la relation de confiance avec l’équipe de la première mise en place de dialyse, puis par le souhait d’être suivis dans une structure polyvalente. /AbstractText AbstractText Label DISCUSSION Si la distance restait le facteur décisif, les facteurs humains étaient majoritairement cités. /AbstractText AbstractText Label CONCLUSION Il faudrait renforcer les liens entre la première équipe et celle qui prend la suite. /AbstractText
1
1-13
20
access to dialysis services; geographical information systèmes; hemodialysis; patient preference; potential access; revealed access; spatial accessibility; travel distance; travel time
28
Février
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Préférence des patients
dialyse rénale
enregistrements
voyage
accessibilité des services de santé

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Diagnostic et prise en charge du prurit associé à la maladie rénale chronique chez les patients hémodialysés.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38294264
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ndt.2024.60
Lanot A
Misery L
Rostoker G
Testa A
Chauveau P
Touzot M
Florens N
Bataille P
10.1684/ndt.2024.60
Chronic kidney disease-associated pruritus (CKD-aP) is a disabling symptom which is frequent and often underestimated. Pa-MRC has a negative impact on quality of life, and is frequently accompanied by sleep disorders and depression. The approval of difelikefalin – a kappa opioid receptor agonist – in this indication requires updated recommendations. As a first step, secondary causes of pruritus without skin lesions must be ruled out, and general measures taken (emollients, psychological support, optimization of dialysis, normalization of serum calcium, phosphate and PTH in the range proposed by the KGIDO guidelines, treatment of iron deficiency). A therapeutic test with a non-sedating oral antihistamine may be proposed. If this test is negative, Pa-MRC must be strongly suspected, and its intensity (WI-NRS scale) and impact on quality of life assessed. In the case of mild Pa-MRC (WI-NRS 3), only general measures are implemented. If Pa-MRC is moderate to severe (WI-NRS 4), specific treatment with difelikefaline can be initiated for 6 months in addition to general measures. At 3 months, if the response is complete (WI-NRS score 1) or partial (decline 3 points), treatment is continued. At 6 months, if the response is complete, treatment may be discontinued with the patient’s agreement; treatment is maintained if the response is partial. At 3 or 6 months, if response is insufficient (decline 3 points) and/or in the event of intolerance, treatment is discontinued and an alternative treatment (e.g., gabapentinoids, UVB) may be considered after dermatological consultation.Le prurit associé à la maladie rénale chronique (Pa-MRC) est un symptôme invalidant qui est fréquent et souvent sous-estimé. Le Pa-MRC a des conséquences négatives sur la qualité de vie et s’accompagne fréquemment de troubles du sommeil et de dépression. L’approbation de la difélikéfaline – agoniste des récepteurs opioïdes kappa – dans cette indication nécessite l’actualisation des recommandations. Les causes secondaires de prurit sans lésions cutanées doivent être exclues et des mesures générales doivent être prises (émollients, aide psychologique, optimisation de la dialyse, équilibre phosphocalcique avec parathormone [PTH] dans la cible KDIGO [Kidney Disease: Improving Global Outcomes], traitement de la carence martiale). Une épreuve thérapeutique avec un antihistaminique oral non sédatif peut être proposée. En cas de test négatif, il faut fortement suspecter un Pa-MRC et évaluer son intensité (échelle WI-NRS [Worst Itch Numeric Rating Scale]) et son impact sur la qualité de vie. En cas de Pa-MRC léger (WI-NRS 3), seules les mesures générales sont mises en œuvre. Si le Pa-MRC est modéré à sévère (WI-NRS 4), un traitement spécifique par difélikéfaline peut être instauré pour 6 mois en plus des mesures générales. À 3 mois, si la réponse est complète (score WI-NRS 1) ou partielle (baisse 3 points), le traitement est poursuivi. À 6 mois, si la réponse est complète, l’arrêt du traitement peut être envisagé avec l’accord du patient ; il est maintenu en cas de réponse partielle. À 3 ou 6 mois, en cas de réponse insuffisante (baisse 3 points) et/ou d’intolérance, le traitement est interrompu et un autre traitement (par exemple, gabapentinoïdes, ultraviolet de type B [UVB]) peut être envisagé après avis dermatologique.
1
1-11
20
uremic pruritus; chronic kidney disease-associated pruritus; dialysis; chronic kidney disease; difelikefaline; quality of life
31
Janvier
publication avant impression
Accès restreint
article de périodique
humains
qualité de vie
prurit
prurit
prurit
insuffisance rénale chronique
insuffisance rénale chronique
dialyse rénale

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Les temps forts de la transplantation rénale en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38294265
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ndt.2024.63
De Serres SA
Couzi L
10.1684/ndt.2024.63
In 2023, significant advances were made in various areas of kidney transplantation. Firstly, the use of a balanced crystalloid solution in the recipient appears to prevent the delay in graft function, unlike hypothermia in the donor and normothermic pulsatile perfusion. Understanding the pathophysiology of humoral rejection has progressed, highlighting the major role of HLA class II molecules and innate immune cells (NK and monocytes expressing FCGR3A). An automatic Banff classification algorithm has been developed to better categorize biopsies in currently known diagnoses. CXCL10, combined with other variables, seems effective in ruling out rejection, but its role in routine care is yet to be defined. Regarding cytomegalovirus (CMV), letermovir has been proven effective in preventing CMV disease in D R- patients, with fewer hematological side effects. For R patients, monitoring CMV-specific T-cell immunity is suggested to reduce the duration of antiviral prophylaxis. The only innovation in immunosuppression is imlifidase for highly sensitized patients, guided by French recommendations. A new equation for glomerular filtration rate measurement has been developed for kidney transplant recipients, performing well across various analyzed stratifications. Finally, xenotransplantation is making a comeback this year, generating hope. However, the description of early humoral rejections involving innate immune cells indicates that adjustments are still needed before considering its widespread deployment.L’année 2023 a connu des avancées significatives dans plusieurs domaines en transplantation rénale. En premier lieu, l’utilisation d’une solution cristalloïde balancée chez le receveur semble jouer un rôle préventif sur le retard de reprise de fonction contrairement à l’hypothermie chez le donneur et la perfusion pulsatile normothermique. La compréhension de la physiopathologie du rejet humoral a aussi progressé : l’expression des molécules HLA de classe II semble jouer un rôle majeur, ainsi que les cellules immunitaires innées (NK et monocytes exprimant le FCGR3A). Un algorithme de classification automatique de Banff a été mis au point pour aider à mieux classer les biopsies dans les diagnostics actuellement connus. Le CXCL10 couplé à d’autres variables d’intérêt semble être performant pour écarter un diagnostic de rejet, mais sa place dans le soin courant reste à définir. En ce qui concerne le cytomégalovirus (CMV), le letermovir a fait la preuve de son efficacité dans la prévention de la maladie chez les patients D R-, avec moins d’effets indésirables hématologiques. Chez les R , la surveillance de l’immunité cellulaire T spécifique du CMV est proposée pour diminuer la durée de la prophylaxie antivirale. La seule nouveauté en immunosuppression est l’imlifidase pour les patients hyperimmunisés, avec une utilisation encadrée par des recommandations françaises. Une nouvelle équation de mesure du débit de filtration glomérulaire (DFG) a été développée chez le transplanté rénal, fonctionnant bien quelles que soient les stratifications analysées. Enfin, la xénotransplantation revient sur le devant de la scène cette année en suscitant beaucoup d’espoir. Néanmoins, la description de rejets humoraux précoces impliquant des cellules innées montre que des ajustements sont encore nécessaires avant d’envisager son déploiement.
S1
1-9
20
transplantation; rejection; opportunistic infections; xenotransplantation
31
Janvier
publication avant impression
Accès restreint
article de périodique
antiviraux
immunosuppresseurs
humains
transplantation rénale
antiviraux
infections à cytomégalovirus
cytomegalovirus
immunosuppresseurs
rejet du greffon

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Devenir obstétrical des patientes transplantées rénales suivies dans une maternité de type III. Étude rétrospective de 2000 à 2020.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38296107
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00034-5
Reitz A
Rouzaire M
Cahierc R
Pereira B
Lemal R
Garrouste C
Gallot D
10.1016/j.gofs.2024.01.011
AbstractText Label AIM To describe pregnancy outcome of kidney transplant patients till 1 year post-partum. /AbstractText AbstractText Label METHODS This retrospective, monocentric study included 15 kidney transplant patients who presented 18 pregnancy, between January 2000 and January 2020. For each of them, we searched for possible obstetrical, fetal and renal complications and we evaluated renal function before, during and after pregnancy. /AbstractText AbstractText Label RESULTS The live birth rate was 84% (16/19) with an average gestational age at delivery of 37 weeks of gestation. The rate of prematurity was 50% (8/16), gestational diabetes was 16,6% (3/18) and preeclampsia was 27.7% (5/18). Cesarean section was performed in 61,1% (11/18) of cases including, 81.8% (9/11) unplanned surgery. The average birth weight was 2635 grams and 37.5% (6/16) of the newborn were small for gestational age. All patients had stable renal function before conception of pregnancy. We noticed two acute graft rejection during pregnancy with only one resulting in graft loss. 4 patients had a reduced graft function in 12 months of the post-partum. /AbstractText AbstractText Label CONCLUSION Risk of maternal, fetal and renal complications remained high in kidney transplant recipients. Pregnancy should be carefully planned in transplanted women associated with adequate follow-up according to clinical guidelines (normal renal function and blood pressure without proteinuria before pregnancy, no recent graft rejection, period of one year after transplant respected and no teratogenic treatment in the month before pregnancy). /AbstractText
maternal and fœtal complications; pregnancy; renal function; renal transplantation
29
Janvier
S2468-7189(24)00034-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Lupus myocarditis presenting as acute congestive heart failure : A case report.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38301591
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00155-5
Ovaga BE
Zahri S
Mulendele P
Huda A
Bennani G
Charif H
Abbassi I
Haboub M
Drighil A
Habbal R
10.1016/j.ancard.2023.101720
Systemic lupus erythematosus (SLE or lupus) is a disease in which the immune system attacks healthy cells and tissues throughout the body. Lupus myocarditis is a life-threatening condition, observed clinically in 3-9 % of patients with SLE. We report the case of a patient followed for multisystem SLE, presenting with de novo heart failure with severe left ventricular dysfunction revealing lupus myocarditis.
2
101720
73
dysfonction ventriculaire gauche; left ventricular dysfunction; lupus érythémateux systémique; myocardite; myocarditis; systemic lupus erythematosus
30
Avril
S0003-3928(23)00155-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
humains
myocardite
lupus érythémateux disséminé
défaillance cardiaque
dysfonction ventriculaire gauche

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Glaucome primitif à angle ouvert et syndrome d’apnée du sommeil : une revue de la littérature.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38306728
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00574-0
Meurisse PL
Onen F
Zhao Z
Bastelica P
Baudouin C
Bonay M
Labbe A
10.1016/j.jfo.2023.104042
The relationship between glaucoma and Obstructive Sleep Apnea Syndrome (OSAS) has long been discussed, with conflicting study findings. OSAS appears in the most recent studies to be more of an aggravating factor than an independent risk factor for glaucoma. Patients with OSAS may develop a more rapid progression of primary open-angle glaucoma (POAG). OSAS may damage the optic nerve not only by increasing the intraocular pressure (IOP) but also by altering the blood supply to the optic nerve as shown by more recent work with OCT-Angiography. Although the systemic benefits of Continuous Positive Airway Pressure (CPAP) have been demonstrated, few studies have evaluated its effect on the optic nerve. CPAP might act on glaucomatous neuropathy by improving the blood supply to the optic nerve. The study of this mechanism of action might provide new insights into the relationship between OSAS and glaucoma.
2
104042
47
glaucoma; glaucome; nerf optique; oct-angiographie; oct-angiography; obstructive sleep apnea syndrome; optic nerve; syndrome d’apnée obstructive du sommeil
01
Février
S0181-5512(23)00574-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
glaucome à angle ouvert
glaucome à angle ouvert
glaucome à angle ouvert
glaucome
Pression intraoculaire
nerf optique
syndrome d'apnées obstructives du sommeil
syndrome d'apnées obstructives du sommeil
syndrome d'apnées obstructives du sommeil

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Actualisation des indications et techniques de reconstruction mammaire immédiate, notamment en cas de radiothérapie adjuvante.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38307494
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00038-2
Vincent L
Laville C
Jacinto S
Coutant C
Burnier P
10.1016/j.gofs.2024.01.015
In 2023, 62,000 patients were diagnosed with breast cancer in France. Every year, 22,000 mastectomies are performed. Breast reconstruction (BR) should be an integral part of breast cancer management. Yet the MR rate in France is only 28% within 3 years of mastectomy, of which 14% are immediate breast reconstruction (IBR). The number of contraindications to RMI has steadily declined over the last few decades, although some of them remain definitive, such as inflammatory cancer (T4d).Today, many specialists involved in the management of breast cancer consider that IBR can be proposed in cases where adjuvant chemotherapy and/or radiotherapy is indicated, if it is not expected to delay carcinological management. The surgical team must then inform the patient of all available BR techniques. If a team does not offer a particular technique, the patient should be referred to a center that does. In all cases, the proposal for curative and reparative treatment should be the subject of a multidisciplinary discussion involving, in particular, a surgeon, a radiotherapist and a medical oncologist.When adjuvant radiotherapy is indicated, the patient must be informed of the increased risk of complications and deterioration of the aesthetic result. In this indication, RMI by prosthesis is a validated technique. However, if the patient has a history of radiotherapy, autologous techniques should be preferred.In a context of shared decision-making, the choice of whether or not to undergo MR and the type of technique must ultimately be made by the patient, in agreement with the multidisciplinary team.
3
165-169
52
breast cancer; breast prosthesis; chemotherapy; radiotherapy; reconstruction
31
Mars
S2468-7189(24)00038-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Femelle
radiothérapie adjuvante
mastectomie
tumeurs du sein
tumeurs du sein
mammoplastie
traitement médicamenteux adjuvant

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Vaccination contre la varicelle, grossesse et allaitement : un état des lieux.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38309510
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00035-7
Vauzelle C
Elefant E
Coulm B
Latour M
Beghin D
Marin B
10.1016/j.gofs.2024.01.012
The varicella vaccine is recommended for women with no history of varicella who are planning to become pregnant, as well as for post-pregnancy women, to prevent the occurrence of this illness and its severe complications, especially an embryopathy, when it occurs in a pregnant woman (congenital varicella syndrome). This live attenuated vaccine should not be administered during pregnancy, nor in the month preceding it. However, when this occurs inadvertently, the data collected on the outcomes of exposed pregnancies, although few in women seronegative at the time of vaccination, allow to reassure the patients to date, as no congenital varicella syndrome has been reported to date following accidental vaccination in early pregnancy. On the other hand, during breastfeeding, a woman may be vaccinated if there is an expected short- or medium-term benefit (varicella exposure, planned pregnancy …).
vaccin varicella; varicella vaccine; allaitement; breastfeeding; grossesse; pregnancy
01
Février
S2468-7189(24)00035-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Accouchement voie basse spontané compliqué d’un abcès du muscle ilio-psoas. À propos d’un cas et revue de la littérature.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38309511
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00036-9
Asma D
Bilel G
Hini JD
10.1016/j.gofs.2024.01.013
01
Février
S2468-7189(24)00036-9
publication avant impression
Accès restreint
lettre

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Maladie de Rosai-Dorfman à localisation orbito-palpébrale de l’enfant : à propos d’une observation exceptionnelle.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38310692
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00015-9
Wade B
Lame CA
Ndiaye Sow MN
Ndiaye A
Diédhiou F
Diakhaté M
Sarr ELHS
Seck SM
Faye AD
Gueye NN
10.1016/j.jfo.2024.104070
AbstractText Label INTRODUCTION Rosai-Dorfman disease (RDD) is a sinus histiocytosis with massive lymphadenopathy. This rare condition is a benign disease of unknown etiology. Bilateral orbital localization of RDD is rare. /AbstractText AbstractText Label OBSERVATION The authors report the case of a 6-year-old child who presented with bilateral orbital-palpebral masses associated with chronic cervical lymphadenopathy. There were no laboratory signs of inflammation. Serological and tuberculosis screening tests were negative. Histopathological examination of a lymph node biopsy established a diagnosis of Rosai-Dorfman disease. The patient underwent surgical excision of the orbital lesions followed by long-term corticosteroid therapy. A favorable course was observed, with no sign of recurrence after one year of follow-up. /AbstractText AbstractText Label CONCLUSION Rosai-Dorfman disease is very rare in its bilateral orbital presentation. Histopathological diagnosis remains challenging. In Africa, the presence of chronic oculo-palpebral tumor associated with or without cervical lymphadenopathy must raise the suspicion of Rosai-Dorfman disease after ruling out tuberculosis and lymphoma. /AbstractText
2
104070
47
enfant; histiocytose sinusale; maladie de rosai-dorfman; orbital tumor; pediatric; rosai-dorfman disease; sinus histiocytosis; tumeur orbitaire
03
Février
S0181-5512(24)00015-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
humains
enfant
histiocytose sinusale cytophagique
histiocytose sinusale cytophagique
histiocytose sinusale cytophagique
maladies de l'orbite
maladies de l'orbite
biopsie
tuberculose

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Prise en charge de première intention du couple infertile: Mise à jour des RPC 2010 du CNGOF.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38311310
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00037-0
Sonigo C
Robin G
Boitrelle F
Fraison E
Sermondade N
Argent EM
Bouet PE
Dupont C
Creux H
Peigné M
Pirrello O
Trombert S
Lecorche E
Dion L
Rocher L
Arama E
Bernard V
Monnet M
Miquel L
Birsal E
Boukobza SH
Plotton I
Ravel C
Martin VG
Huyghe E
Dupuis HGA
Lefevre T
Leperlier F
Bardet L
Lalami I
Robin C
Simon V
Dijols L
Riss J
Koch A
Bailly C
Rio C
Lebret M
Jegaden M
Fernandez H
Pouly JL
Torre A
Antoine JM
Courbiere B
10.1016/j.gofs.2024.01.014
AbstractText Label OBJECTIVE To update the 2010 CNGOF clinical practice guidelines for the first-line management of infertile couples. /AbstractText AbstractText Label MATERIALS AND METHODS Five major themes (first-line assessment of the infertile woman, first-line assessment of the infertile man, prevention of exposure to environmental factors, initial management using ovulation induction regimens, first-line reproductive surgery) were identified, enabling 28 questions to be formulated using the PICO (Patients, Intervention, Comparison, Outcome) format. Each question was addressed by a working group that had carried out a systematic review of the literature since 2010, and followed the GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology to assess the quality of the scientific data on which the recommendations were based. These recommendations were then validated during a national review by 40 national experts. /AbstractText AbstractText Label RESULTS The fertility work-up is recommended to be prescribed according to the woman's age: after one year of infertility before the age of 35 and after 6 months after the age of 35. A couple's initial infertility work-up includes a single 3D ultrasound scan with antral follicle count, assessment of tubal permeability by hysterography or HyFOSy, Anti Mullerian hormone assay prior to assisted reproduction, and vaginal swabbing for vaginosis. If the 3D ultrasound is normal, hysterosonography and diagnostic hysteroscopy are not recommended as first-line procedures. Chlamydia trachomatis serology does not have the necessary performance to predict tubal patency. Post-coital testing is no longer recommended. In men, spermogram, spermocytogram and spermoculture are recommended as first-line tests. If the spermogram is normal, it is not recommended to check the spermogram. If the spermogram is abnormal, an examination by an andrologist, an ultrasound scan of the testicles and hormonal test are recommended. Based on the data in the literature, we are unable to recommend a BMI threshold for women that would contraindicate medical management of infertility A well-balanced Mediterranean-style diet, physical activity and the cessation of smoking and cannabis are recommended for infertile couples. For fertility concern, it is recommended to limit alcohol consumption to less than 5 glasses a week. If the infertility work-up reveals no abnormalities, ovulation induction is not recommended for normo-ovulatory women. If intrauterine insemination is indicated based on an abnormal infertility work-up, gonadotropin stimulation and ovulation monitoring are recommended to avoid multiple pregnancies. If the infertility work-up reveals no abnormality, laparoscopy is probably recommended before the age of 30 to increase natural pregnancy rates. In the case of hydrosalpinx, surgical management is recommended prior to ART, with either salpingotomy or salpingectomy depending on the tubal score. It is recommended to operate on polyps 10 mm, myomas 0,1,2 and synechiae prior to ART. The data in the literature do not allow us to systematically recommend asymptomatic uterine septa and isthmoceles as first-line surgery. /AbstractText AbstractText Label CONCLUSION Based on strong agreement between experts, we have been able to formulate updated recommendations in 28 areas concerning the initial management of infertile couples. /AbstractText
amh; infertility; ovulation induction; spermogram
02
Février
S2468-7189(24)00037-0
publication avant impression
Accès restreint
résumé en anglais
guide de bonnes pratiques

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Impact de la méthode diagnostique du trouble de personnalité borderline sur la réponse aiguë et le risque de rechute précoce chez les individus déprimés majeurs traités par ECT : une revue systématique de la littérature.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38311474
https://linkinghub.elsevier.com/retrieve/pii/S0013-7006(24)00011-3
Bamouss A
Mungo A
Hein M
10.1016/j.encep.2023.11.021
AbstractText Label INTRODUCTION Given the contradictory data available in the literature, the aim of this systematic review was to investigate the impact of the diagnostic method for borderline personality disorder (BPD) on the acute response and the risk of early relapse in major depressed individuals treated with electroconvulsive therapy (ECT). /AbstractText AbstractText Label METHOD After a systematic literature review performed during March 2023 in the PubMed-Medline database according to the PRISMA criteria, 47 articles were identified using the keyword algorithm (Electroconvulsive Therapy [Mesh] or electroconvulsive therapy) and (Borderline Personality Disorder [Mesh] or borderline personality disorder). The inclusion criteria applied for the selection of articles in this systematic review were: (1) articles investigating the impact of BPD on the acute response and/or the risk of early relapse in major depressed individuals ( 18 years old) treated with ECT, (2) diagnosis of BPD and major depressive disorder by validated screening tests and/or systematic psychiatric interviews based on diagnostic criteria of international classification, (3) any type of study (cross-sectional, longitudinal, prospective, retrospective, interventional and experimental), (4) articles written in English or French, and (5) articles published after January 2000. After assessment of the 47 articles based on these inclusion criteria by two authors, seven studies investigating the impact of BPD diagnosed by systematic psychiatric interview or screening tests on the acute response and the risk of early relapse in major depressed individuals treated with ECT were included in this systematic review. /AbstractText AbstractText Label RESULTS Unlike the three studies diagnosing BPD by screening tests, the four studies diagnosing BPD by systematic psychiatric interview demonstrated a negative impact of this personality disorder on the acute response or the risk of early relapse in major depressed individuals treated with ECT. However, all studies included in this systematic review presented a low level of scientific evidence (cross-sectional epidemiological studies and retrospective cohort studies). /AbstractText AbstractText Label CONCLUSION Despite the need for studies of better scientific quality, the results of this systematic review seem to indicate that screening for BPD by systematic psychiatric interview during the pre-ECT assessment and the establishment of adequate therapeutic strategies in case of comorbid BPD could be promising options to allow better acute response and better prevention of early relapses in major depressed individuals treated with ECT. /AbstractText
borderline personality disorder; depressive relapse; electroconvulsive therapy; major depressive disorder; rechute dépressive; réponse au traitement; treatment response; trouble de personnalité borderline; trouble dépressif majeur; électroconvulsivothérapie
03
Février
S0013-7006(24)00011-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Accès à la transplantation rénale des patients en insuffisance rénale chronique terminale dans les pays du Maghreb : état des lieux et recommandations.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38314548
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ndt.2024.62
Marie-Alice M
Mohamed Mongi B
Amel S
Inass L
Imen S
Christian J
Fateh M
Said Y
Rached B
Jalel Z
Abed El Kader N
Naïma B
Hélène N
Agathe G
Laurent D
Taieb BA
Michel T
10.1684/ndt.2024.62
We present an overview of kidney transplantation activity in the Maghreb countries, based on data from the 9th Colloque France-Maghreb (Paris, May 20 and 21, 2022). For Algeria, Morocco and Tunisia, the incidence of end stage renal failure is respectively 120, 130 and 130 per million inhabitants, its prevalence 626, 900 and 833 per million inhabitants and the part of patients with a functional graft of 10.3, 1.8 et 8.5% with an annual number of transplants of 6.5, 0.8 and 8.7 per million inhabitants. Living donor transplants account for 99% of transplants in Algeria, 93% in Morocco and 80% in Tunisia. In conclusion, access to transplantation remains low in the Maghreb countries. All the modalities (living donor with enlargement of the circle of donors, deceased donors) must be further developed. Recommendations were issued to support activity.Nous présentons un état des lieux de l’activité de transplantation rénale dans les pays du Maghreb à partir des données du 9e Colloque France-Maghreb (Paris, 20 et 21 mai 2022). Pour l’Algérie, le Maroc et la Tunisie, l’incidence de l’insuffisance rénale chronique terminale est respectivement de 120, 130 et 130 par million d’habitants, sa prévalence de 626, 900 et 833 par million d’habitants et la part des patients porteurs d’un greffon fonctionnel est de 10,3, 1,8 et 8,5 % avec un nombre annuel de transplantations de 6,5, 0,9 et 7,7 par million d’habitants. La transplantation avec donneur vivant représente 99 % des transplantations en Algérie, 93 % au Maroc et 80 % en Tunisie. En conclusion, l’accès à la transplantation reste faible dans les pays du Maghreb. Toutes les modalités (donneur vivant avec élargissement du cercle des donneurs, donneurs décédés) doivent être développées. Des recommandations ont été émises pour soutenir cette activité.
1
1-11
20
chronic renal insufficiency; dialysis; epidemiology; maghreb; renal transplantation
05
Février
publication avant impression
Accès restreint
article de périodique
revue de la littérature
humains
transplantation rénale
Algérie
Tunisie
défaillance rénale chronique
défaillance rénale chronique
donneur vivant

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Influence de l’immersion dans l’eau sur le recours à la péridurale pendant le travail.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38316256
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00039-4
Kacha N
Dorel G
Frappé P
Chauleur C
Raia-Barjat T
10.1016/j.gofs.2024.01.016
AbstractText Label OBJECTIVE immersion in water during labor could reduce pain and use of epidural anesthesia during childbirth. The main objective of this study was to evaluate the influence of immersion in water during labor on the use of epidural anesthesia in a midwife care setting. /AbstractText AbstractText Label METHODS We conducted a single-center retrospective study of all women who gave birth in the physiological ward of Saint-Etienne University Hospital between October 2020 and December 2022. /AbstractText AbstractText Label RESULTS The study did not find difference between immersion group and control group concerning the use of epidural anesthesia (p 0.49). The immersion group counted more women with a duration of labor greater than 6 hours than in the control group. The multivariate analysis adjusted for parity and duration of labor did not find difference between both groups (OR 0.58; 95% CI [0.30; 1.09]). /AbstractText AbstractText Label CONCLUSION Even if it does not seem to modify the use of epidurals, immersion in water does not seem to increase maternal and neonatal morbidity and mortality. It represents a therapeutic alternative with reasonable cost to offer for pregnant women who wish to give birth without epidural anesthesia. /AbstractText
accouchement; anesthésie péridurale; childbirth; douleurs; epidural anesthesia; immersion; labor; pain; travail; water immersion
03
Février
S2468-7189(24)00039-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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État des lieux de la mise en place en France des entretiens pharmaceutiques en officine : analyse des réponses issues d’un questionnaire.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38158271
https://linkinghub.elsevier.com/retrieve/pii/S0040-5957(23)00195-6
Barat E
Pouant C
Soubieux A
Arrii M
Bardet JD
Chenailler C
Varin R
10.1016/j.therap.2023.11.010
AbstractText Label OBJECTIVE To evaluate the development of pharmaceutical interviews in pharmacies in France, in order to understand the organization implemented, any limitations and the expansion of eligible pathologies. /AbstractText AbstractText Label METHOD A dematerialized questionnaire was designed and distributed between November 2022 and February 2023 to pharmacists and pharmacy students in France (mainland and overseas) via a link to a Google Form. /AbstractText AbstractText Label RESULTS Ninety-four pharmacists from 8 different regions of France responded to the survey. The 94 responses showed that 56% of pharmacists practiced pharmaceutical interviews. Among pharmacists who practiced interviews, pharmacy owners practiced significantly more interviews than other statuses within the pharmacy (67% vs. 38% P 0.014). No other factor, such as dispensary size or geographical area of practice, had a significant impact on whether or not pharmaceutical interviews were carried out. These talks are often carried out at the patient's request, and 89% of them are accompanied by documents for the patient's attention. For pharmacists who do not carry out interviews, time, staffing and remuneration are the 3 main blocking factors found in both quantitative and verbatim variables. Whether or not pharmacists carry out pharmaceutical interviews, this activity received 87% approval from the 94 respondents, and 84% of them would like to include more chronic disease themes. /AbstractText AbstractText Label CONCLUSION The survey shows that pharmacists approve of the pharmaceutical interviewing activity, but it also highlights obvious logistical obstacles linked to a lack of resources. Thus, even among pharmacists who carry out pharmaceutical interviews, this activity is still carried out relatively infrequently on a routine basis, and often by the incumbent pharmacist, who takes on the responsibility of carrying out this activity. /AbstractText
entretiens pharmaceutiques; iatrogeny; iatrogénie; officine; parcours patient; patient pathway; pharmaceutical care; pharmaceutical interviews; pharmacy; soins pharmaceutiques
16
Décembre
S0040-5957(23)00195-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Une hémoptysie.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38158293
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01323-1
El Amrani S
Imrani K
Charlemagne KEM Jr
Moatassim Billah N
Nassar I
10.1016/j.revmed.2023.12.006
angioscanner; ct angiography; hemoptysis; hémoptysie; pulmonary sequestration; séquestration pulmonaire
28
Décembre
S0248-8663(23)01323-1
publication avant impression
Accès restreint
article de périodique

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Gestion des toxicités des immunothérapies du cancer : challenges et « rechallenges » pour les (jeunes) internistes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38158294
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01320-6
Guitton R
Lambotte O
Chiche L
10.1016/j.revmed.2023.12.003
1
1-5
45
autoimmune diseases; cancer immunotherapy; effets indésirables immuno-médiés; immune checkpoint inhibitor; immune-related adverse events; immunothérapie anticancéreuse; inhibiteur du point de contrôle; internal medicine; maladies auto-immunes; médecine interne
28
Janvier
S0248-8663(23)01320-6
publication avant impression
Accès restreint
article de périodique
humains
immunothérapie
tumeurs

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Diagnostic et évaluation de l’hépatopathie stéatosique métabolique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38158295
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)00880-9
Canivet CM
Faure S
10.1016/j.revmed.2023.10.438
Non-alcoholic fatty liver disease (NAFLD) or recently called Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD), is the leading cause of liver disease, with an estimated worldwide prevalence of 25%. MASLD is suspected, in a metabolic condition, in the presence of hepatic steatosis, moderate hepatic cytolysis or hyperferritinemia. The severity of the disease depends on the stage of liver fibrosis, which can be suspected in clinical practice by simple blood tests such as the FIB-4 or NAFLD fibrosis Score. The treatment is based on lifestyle intervention combining weight loss, increased physical activity and a Mediterranean-style diet. Only a small minority of patients with MASLD will develop advanced liver disease and require liver specialist. Given the high prevalence of MASLD, the identification of these patients cannot be envisaged without the taking part in the screening of all physicians (general practitioners and specialists).
1
41-47
45
cirrhose; cirrhosis; fibrose hhépatique; liver fibrosis; masld; metabolic syndrome; nafld; non-invasive liver fibrosis test; syndrome métabolique; test non invasif de fibrose hépatique
28
Janvier
S0248-8663(23)00880-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
Stéatose hépatique non alcoolique
Stéatose hépatique non alcoolique
Stéatose hépatique non alcoolique
maladies métaboliques
médecins généralistes
mode de vie

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Étude comparative des processus de production et de contrôle analytique des préparations magistrales de mélanges nutritifs parentéraux en néonatalogie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38159720
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(23)00167-0
Bosson A
Durand M
Mazet R
Romaszko MJ
Chennell P
Mounsef F
Quessada T
Choisnard L
Bedouch P
10.1016/j.pharma.2023.12.009
AbstractText Label OBJECTIVES To assess the impact of disparities in production and analytical control processes on the quality of parenteral nutrition (PN) preparations produced in the Auvergne-Rhône-Alpes region. /AbstractText AbstractText Label METHODS This study was carried out in four hospital pharmacies of the Auvergne-Rhône-Alpes region. To assess the impact of production processes, each centre produced ten PN preparations from the same prescription. Analytical controls (sodium, potassium and calcium dosage) were carried out on all the preparations. To assess the impact of the control processes, a batch of ten preparations was produced from the same prescription. Samples were sent to the four hospital pharmacies for analytical control (sodium, potassium and calcium dosage). /AbstractText AbstractText Label RESULTS Measurements of relative production bias show that there is a significant difference between the preparations from the four centres in terms of sodium and potassium content. Each centre had at least one production bias for one of the three electrolytes measured. Concerning analytical controls, there was a significant difference between the four centres in the sodium and potassium levels measured. With the exception of calcium, all the centres reported measurements within the usual specifications of /-10% of the target value. The results obtained have no clinically significant impact. /AbstractText AbstractText Label CONCLUSION The diversity of NP practices has a real impact on the quality of the preparations made. A regional collaboration should be envisaged to standardise patient care. /AbstractText
2
306-317
82
compounding; hospital pharmacy; parenteral nutrition; quality control
28
Mars
S0003-4509(23)00167-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
calcium
sodium
potassium
humains
néonatologie
nutrition parentérale

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Infarctus du myocarde sans artères coronaires obstructives : rôle central de l’imagerie.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38160097
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)00765-8
Sedoud B
Barone-Rochette G
10.1016/j.revmed.2023.10.455
Myocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions ( 6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order to identify the etiological mechanism, and thus set up a suitable treatment. Many tools are available to support diagnosis, notably in the fields of imaging, the principal contributors being coronary angiography, coronary physiology and pharmacological testing, as well as endo-coronary imaging and cardiac MRI. This review will provide an update on the definition, epidemiology, diagnostic strategies and treatment options for patients with MINOCA.
cardiovascular imaging; endo-coronary imaging and cardiac mri; imagerie cardiovasculaire; imagerie endocoronaire et irm cardiaque; minoca
29
Décembre
S0248-8663(23)00765-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

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L’haploinsuffisance de A20 : que doit connaître le clinicien?
2023
http://www.ncbi.nlm.nih.gov/pubmed/38160098
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01321-8
Elhani I
Aouba A
Riller Q
Vergneault H
Boursier G
Rieux-Laucat F
Hentgen V
Georgin-Lavialle S
10.1016/j.revmed.2023.12.004
A20 Haploinsufficiency (HA20) is a monogenic autoinflammatory disease associated with an autosomal dominant mutation in the TNFAIP3 gene. It induces a defect in the inactivation of the pro-inflammatory NF-κB pathway. Less than 200 cases have been described worldwide. The clinical picture of the disease is essentially based on the association of recurrent fever and/or biologic inflammatory syndrome, aphtosis, often bipolar, and cutaneous folliculitis. However, the clinical spectrum of HA20 is very broad, including gastrointestinal (mainly colonic ulceration), articular, cutaneous, pericardial and lymph node involvement, as well as frequent association with organ-specific or non-specific autoimmune manifestations and/or autoantibodies, including antinuclear antibodies and anti-dsDNA. As a result, the diagnosis of a number of systemic or organic disorders, most notably Behçet's disease, Crohn's disease, and sometimes even systemic lupus, has been corrected to HA20 by molecular research for a heterozygous mutation with functional deficiency of TNFAIP3. Although the first signs of the disease often appear in the first years of life, the diagnosis is often made in adulthood and requires the involvement of both paediatric and adult physicians. Treatment for HA20 is not codified and relies on conventional or biological immunomodulators and immunosuppressants adapted to the patient's symptomatology. This review highlights the enormous diagnostic challenges in this autoinflammatory disease.
a20 haploinsufficiency; autoimmunity; autoimmunité; autoinflammatory disease; haploinsuffisance de a20; maladie autoinflammatoire; maladie de behcet; tnfaip3; maladie de crohn
29
Décembre
S0248-8663(23)01321-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

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Utilisation des anti-infectieux au sein d’un centre hospitalier universitaire mère–enfant au Canada : une étude observationnelle.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38160789
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(23)00170-0
Monnier A
Roy H
Blackburn J
Bussières JF
10.1016/j.pharma.2023.12.012
AbstractText Label INTRODUCTION The proper use of antimicrobials is a challenge in healthcare establishments. /AbstractText AbstractText Label OBJECTIVES Describe the detailed antimicrobial consumption profile in 2021-2022. Describe the annual evolutionary profile of the use of antimicrobials in days of therapy/1000 patient days, antibiotic spectrum index/1000 patients days and according to the proportion of days of therapy administered by parenteral route from 2005-2006 to 2021-2022. /AbstractText AbstractText Label METHOD Descriptive and retrospective study. All patients admitted to our mother-child hospital center between April 1, 2005 and March 31, 2022 were included. The study covers the consumption of all antimicrobials through the AWaRe classification of the World Health Organization and antibiotic spectrum index. /AbstractText AbstractText Label RESULTS A total of 673.9 days of therapy/1000patients days was calculated in 2021-2022, i.e. 550.8 for antibiotics, 46.5 for antivirals, 67.9 for antifungals and 8.7 for others. A total of 2436 ASI/1000 patient days was calculated in 2021-2021. According to the AWaRe classification, in 2021-2022, 52.1% (287/551) of days of therapy/1000patients days referred to the Access group, 47.8% (263/551) to the Watch group and 0.2% (1/551) to the Reserve group. /AbstractText AbstractText Label CONCLUSION This study aims to explore the use of antimicrobials in a mother-child hospital center. It puts into perspective a stable or even slightly decreasing use of a selection of antimicrobials and compares favorably with published data. Antibiotic governance is based in particular on the periodic evaluation of consumption. Our study illustrates different approaches to quantify and describe this use. /AbstractText
2
318-328
82
asi; antibiotic stewardship; antimicrobials; treatment days; utilization
29
Mars
S0003-4509(23)00170-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
étude d'observation
anti-infectieux
antibactériens
humains
études rétrospectives
anti-infectieux
antibactériens
hôpitaux universitaires
Canada
relations mère-enfant

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La Commission de la transparence de la Haute Autorité de santé.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38176970
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00485-X
Lengliné E
10.1016/j.bulcan.2023.12.002
The Transparency Committee (TC) in France plays a crucial role in the evaluation of post-market authorization (MA) drugs for reimbursement by the social security system. Although its organization has evolved since its creation, the principle of its existence has persisted since the establishment of the social security system. The TC, transitioning from the Medicines Agency to the Haute Autorité de santé in 2005, focuses on the medico-scientific evaluation of drugs, influencing decisions on reimbursement eligibility and price negotiations. It assesses the benefit and added medical value of drugs. Comprising experts with no conflicts of interest with pharmaceutical companies, the TC conducts a scientific evaluation of submissions by pharmaceutical laboratories. Recently, it has also been involved in evaluating requests for early access authorization prior to MA.
2
228-234
111
drugs; evaluation; health technology assessment; industrie pharmaceutique; médicament; pharmaceutical industry; régulation; évaluation
03
Février
S0007-4551(23)00485-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
préparations pharmaceutiques
humains
France

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Corrigendum à l’article « Nouvelles AMMs européenne : utilisation du zanubrutinib en monothérapie dans le traitement de la leucémie lymphoïde chronique » [Bull Cancer 2023;110:744–745].
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182437
Thiam M
Cavalieri D
10.1016/j.bulcan.2023.12.001
04
Janvier
S0007-4551(23)00483-6
publication avant impression
Accès restreint
erratum publié

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Qu’est-ce que 2023 aura permis de changer dans nos pratiques en cancérologie ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38184423
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00486-1
Bay JO
Auberger B
Bouleuc C
Cohen R
Delom F
Firmin N
Gandemer V
L'Allemain G
Magne N
De Nonneville A
Orbach D
Pellier I
Rodrigues M
Wislez M
pour le comité de rédaction du Bulletin du Cancer
10.1016/j.bulcan.2023.12.003
In 2023, the improvement of our therapeutic management has largely taken shape. The aim of our article is to highlight the major advances that will change our practices. These are not only in the field of treatment, but also in the improvement of supportive care. Here, we present these new developments organ by organ, cancer by cancer. You can read everything or concentrate on the cancers that are your areas of expertise. But this exhaustiveness should be representative of our current state of progress.
1
18-32
111
actualités 2023 en cancérologie; new treatments in oncology; nouveaux traitements; updates in 2023
05
Janvier
S0007-4551(23)00486-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
tumeurs
oncologie médicale

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Les Printemps de la Médecine Interne : l’intelligence artificielle face aux experts internistes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38331591
Albaladejo A
Lorleac'h A
Allain JS
10.1016/j.revmed.2024.01.012
AbstractText Label INTRODUCTION The Printemps de la Médecine Interne are training days for Francophone internists. The clinical cases presented during these days are complex. This study aims to evaluate the diagnostic capabilities of non-specialized artificial intelligence (language models) ChatGPT-4 and Bard by confronting them with the puzzles of the Printemps de la Médecine Interne. /AbstractText AbstractText Label METHOD Clinical cases from the Printemps de la Médecine Interne 2021 and 2022 were submitted to two language models: ChatGPT-4 and Bard. In case of a wrong answer, a second attempt was offered. We then compared the responses of human internist experts to those of artificial intelligence. /AbstractText AbstractText Label RESULTS Of the 12 clinical cases submitted, human internist experts diagnosed nine, ChatGPT-4 diagnosed three, and Bard diagnosed one. One of the cases solved by ChatGPT-4 was not solved by the internist expert. The artificial intelligence had a response time of a few seconds. /AbstractText AbstractText Label CONCLUSIONS Currently, the diagnostic skills of ChatGPT-4 and Bard are inferior to those of human experts in solving complex clinical cases but are very promising. Recently made available to the general public, they already have impressive capabilities, questioning the role of the diagnostic physician. It would be advisable to adapt the rules or subjects of future Printemps de la Médecine Interne so that they are not solved by a public language model. /AbstractText
artificial intelligence; bard; case report; chatgpt; diagnostic; intelligence artificielle
07
Février
S0248-8663(24)00032-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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La chimiothérapie intra-péritonéale dans le traitement de la carcinose péritonéale d’origine colorectale. CHIP, PIPAC, état des lieux et perspectives.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38331695
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00423-X
Quénet F
Carrère S
Sgarbura O
10.1016/j.bulcan.2023.10.006
After more than a decade of good results using the combination of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) in the treatment of peritoneal carcinosis of colorectal origin, the PRODIGE7 study, which specifically evaluated the role of HIPEC, failed to show any superiority in terms of overall and disease-free survival for the CRS HIPEC combination compared with CRS alone. This study constituted a radical change in the knowledge and therapeutic attitudes observed to date. After reviewing the literature and the consensus of national and international experts, a synthesis is provided, together with an outlook on the questions raised and the therapeutic trials and innovations of the near future. An analysis of recent advances due to the advent of a new technique, PIPAC, is also proposed, as well as a review of current therapeutic trials in this field.
3
285-290
111
chip; cancer colorectal; carcinose péritonéale; chirurgie de cytoréduction; colorectal cancer; cytoreductive surgery; hipec; pipac; peritoneal carcinomatosis
07
Mars
S0007-4551(23)00423-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
hyperthermie provoquée
perfusion régionale de chimiothérapie anticancéreuse
tumeurs colorectales
carcinomes
tumeurs du péritoine
association thérapeutique
protocoles de polychimiothérapie antinéoplasique
taux de survie

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Référentiel national de traitement des carcinomes épidermoïdes des voies aérodigestives supérieures.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38336530
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00016-X
Dolivet G
Barry B
Abdeddaim C
Baujat B
Blanchard N
Calais G
Carrat X
Chatellier A
Clatot F
Coste F
Cupissol D
Cuvelier P
de Mones Del Pujol E
Deneuve S
Duffas O
Dupret-Bories A
Even C
Evrard C
Evrard D
Faivre S
Fakhry N
Garrel R
Gorphe P
Houliat T
Huguet F
Kaminsky MC
Krebs L
Lapeyre M
Lindas P
Malard O
Mirghani H
Mondina M
Moriniere S
Mouawad F
Pestre-Munier J
Pham Dang N
Picard A
Ramin L
Renard S
Salvan D
Schernberg A
Sire C
Thariat J
Vanbockstael J
Vo Tan D
Wojcik T
Klein I
Block V
Baumann-Bouscaud L
de Raucourt D
10.1016/j.bulcan.2023.08.015
4
327-332
111
08
Avril
S0007-4551(24)00016-X
publication avant impression
Accès restreint
éditorial
humains
carcinome épidermoïde
carcinome épidermoïde
tumeurs de la tête et du cou

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Dépôts immuns le long des basales tubulaires au cours de la néphropathie à BK virus.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38336535
Belgaid YC
Moktefi A
10.1016/j.annpat.2024.01.009
08
Février
S0242-6498(24)00034-8
publication avant impression
Accès restreint
article de périodique

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Une tumeur maligne rare de la veine rénale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38336536
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00227-4
Mouaddine A
Thiebaut PA
Sabourin JC
10.1016/j.annpat.2023.11.001
The renal vein is an exceptional location for leiomyosarcoma, an aggressive malignant tumor of smooth-muscle origin with a poor prognosis. We report the case of a 55-year-old female patient who consulted for left flank pain that had been present for 6 months. A CT scan revealed a 9.4cm left retroperitoneal mass in contact with the psoas muscle, left kidney, stomach, spleen, left colon and extending up to the pancreas, raising the suspicion of a tumour originating in the retroperitoneal tissues. A biopsy revealed a smooth-muscle cell tumour with a degree of malignancy difficult to define. The patient underwent a monobloc left compartmentectomy, which led to the diagnosis of leiomyosarcoma of the left renal vein. A review of the literature on these rare tumours in this location is presented.
2
137-141
44
leiomyosarcoma; léiomyosarcome; renal vein; veine rénale
08
Mars
S0242-6498(23)00227-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
présentations de cas
Femelle
humains
adulte d'âge moyen
veines rénales
léiomyosarcome
léiomyosarcome
léiomyosarcome
tomodensitométrie
tumeurs du rein
tumeurs du rein
tumeurs du rein

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Un péricarde coloré.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38336537
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00030-0
Pham F
Boulagnon-Rombi C
10.1016/j.annpat.2024.01.007
2
152-153
44
08
Mars
S0242-6498(24)00030-0
publication avant impression
Accès restreint
article de périodique
présentations de cas

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Une cystite compliquée.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38336584
Martin-Lecamp G
Vandenhende MA
Meriglier E
10.1016/j.revmed.2024.01.013
cystite emphysémateuse; emphysematous cystitis; infection urinaire; urinary tract infection
08
Février
S0248-8663(24)00033-X
publication avant impression
Accès restreint
article de périodique

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Office white-coat effect tail: A useful tool in family practice?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38340382
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(24)00012-X
Humbert X
Touze E
Le Bas J
Schonbrodt L
Couette PA
De Jaegher S S
Pithon A
Alexandre J
Puddu PE
10.1016/j.ancard.2024.101733
AbstractText Label BACKGROUND White coat effect (WCE) and white coat hypertension (WCH) are hardly both compared in primary care. /AbstractText AbstractText Label OBJECTIVE To assess the usefulness of repeated measures of systolic blood pressure (SBP) to dissociate various forms of white-coat interactions. /AbstractText AbstractText Label METHODS An open cross-sectional study on consecutive patients treated or not for high blood pressure was made in family physicians' offices. SBP was measured 5 times by an electronic device. Measurements were performed before (SBP1) and after (SBP5) the office visit by a lay assistant and at the beginning (SBP2), middle (SBP3) and end (SBP4) of visit, by the family physician. Home BP (HBPM) was measured from 3 consecutive days by the patient. WCE and office WCE tail (OWCET) were defined, respectively, as a 10 mmHg SBP increase or decrease between SBP2-SBP1 or SBP4-SBP2. WCH was considered when HBPM was normal (SBP 135 mmHg) at home and high during the SBP2 office visit. /AbstractText AbstractText Label RESULTS Two hundred five patients (134 women versus 71 men, ratio 1.9, aged 59.8 15.7 years) were recruited. In categorical terms, there were 51 patients (25%) who presented with WCE, OWCET was seen in 121 patients (62%) and 47 patients (23%) had WCH. Only 36 patients (18%) presented both OWCET and WCE and 32 (16%) had both OWCET and WCH. The receiver operating characteristic curves (ROCs) of OWCET in diagnosing WCE or WCH were respectively 0.67 (p 0.0001) and 0.53 (NS). /AbstractText AbstractText Label CONCLUSION Thus, OWCET was predictive of WCE and not of WCH and it is worthwhile to be measured in the family physician office. /AbstractText
2
101733
73
automesures tensionnelles; blood pressure measurement; effet blouse blanche; home blood pressure; mesure de pression artérielle; white-coat effect
09
Avril
S0003-3928(24)00012-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
Mâle
humains
Femelle
études transversales
hypertension artérielle
hypertension de la blouse blanche
pression sanguine
surveillance ambulatoire de la pression artérielle

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Gaspillage d’héparine sodique dans un centre hospitalo-universitaire français.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38340805
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00007-5
Franchina MP
Charpiat B
10.1016/j.pharma.2024.02.002
AbstractText Label OBJECTIVES In a context of heparin shortage, we studied the wasted quantities in three intensive care units (ICU) of a university hospital where two electric syringe pump (ESP) heparin protocols coexist (20000UI/48mL used in the cardiology ICU and 25000UI/50mL use in the medical and surgical ICUs). /AbstractText AbstractText Label METHOD We performed a prospective observational study of patients treated with heparin ESP. We collected the information recorded in the prescription software connected to the ESP (dosage, start time, infusion rate, interruption times, date and time of end of treatment). We observed the ESPs, noted the time of start written on the label and the quantity remaining, and questioned nurses about the constraints that lead for changing the ESPs. /AbstractText AbstractText Label RESULTS Between 23/03/23 and 19/05/23, 164 vials of 25000UI/5mL were used. The wasted quantity was equivalent 42 vials: 18 vials (43%) of treatment stopped, nurses practices such as changing the ESP in advance 6 vials (14%), application of the rule discard the ESP 24 hours after preparation 9 vials (21.5%) and 9 vials (21.5%) corresponding to the 45 mL discarded for the 45 ESP prepared in the cardiology ICU. /AbstractText AbstractText Label CONCLUSION More than a quarter of the heparin purchased is wasted. The results should lead to policy decisions concerning the medications supply chain, i.e. abandoning the 20000UI/48mL protocol, supply of ready to use heparin syringes by industry or by the pharmacy. It is essential that these data be fed back to nurses teams, in order to gather their suggestions before considering any changes of their practices. /AbstractText
3
575-583
82
electric syringe pump; heparin; protocol; waste
08
Mai
S0003-4509(24)00007-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
étude d'observation
héparine
humains
héparine
hôpitaux universitaires
unités de soins intensifs
pharmacie
études prospectives

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Gestation pour autrui altruiste en France : contexte et perspectives.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38340981
Agopiantz M
Dap M
Mougniotte G
Bertholdt C
Morel O
10.1016/j.gofs.2024.02.001
lgbt; droits reproductifs; femme porteuse; gestation pour autrui (gpa); intended parents; parents d’intention; reproductive rights; surrogacy; surrogate
08
Février
S2468-7189(24)00040-0
publication avant impression
Accès restreint
éditorial

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Un polype vaginal inhabituel.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341310
Pamart J
Catteau X
Noël JC
10.1016/j.annpat.2023.11.002
09
Février
S0242-6498(23)00228-6
publication avant impression
Accès restreint
article de périodique

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La pseudotumeur fibro-osseuse des doigts : une tumeur fibroblastique/myofibroblastique liée à USP6.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341311
El Bejjaj I
Mercier A
Mcleer A
Valmary-Degano S
10.1016/j.annpat.2023.12.004
Fibro-osseous pseudotumor of the digits is a benign tumour closely related to myositis ossificans. It is a rare lesion seldom reported in the literature. We report the case of a 33-year-old woman with lancinating pain in the first phalanx of the second finger of the right hand, associated with inflammation. The histopathological examination of the surgical excision biopsy of the lesion revealed a spindle-shaped proliferation within a sclerosing, hyaline, and osteoid stroma. In our observation, immunohistochemistry and molecular biology are the main elements that helped to establish the diagnosis and eliminate the various differential diagnoses, despite a non-specific histopathological aspect.
benign tumour; biologie moléculaire; fibro-osseous pseudotumour of the digits; gène usp6; immunohistochemistry; immunohistochimie; molecular biology; pseudotumeur fibro-osseuse des doigts; spindle-cell tumour; tumeur bénigne; tumeur à cellules fusiformes; usp6 gene
09
Février
S0242-6498(23)00232-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Tumeur neuroépithéliale avec fusion PATZ1 – à propos d’un cas et mise au point sur une entité mal définie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341312
Fontaine A
Basset L
Milin S
Argentin J
Uro-Coste E
Rousseau A
10.1016/j.annpat.2024.01.002
The neuroepithelial tumor with PATZ1 fusion is a recently described tumor type, at the border between central nervous system and mesenchymal tumors. The histopathological diagnosis of this neoplasm, not recognized by the 2021 WHO classification, is challenging due to its varied and non-specific morphologic features. Most cases are densely cellular with monomorphous nuclei. Perivascular pseudo-rosettes of the ependymal type and astroblastic features are frequent. Blood vessels may be hyalinized. The tumor may display low- or high-grade features. OLIG2 and GFAP are variably expressed. Guided by DNA methylation profiling, a pathologist aware of this tumor type will search for a fusion involving PATZ1 and EWSR1 or MN1. The physiopathology of neuroepithelial tumor with PATZ1 fusion is not fully understood. The prognosis appears to align with that of intermediate-grade tumors but follow-up data are scarce. The therapeutic management is often similar to that of high-grade neoplasms. Nonetheless, PATZ1 fusion is a potential therapeutic avenue that may lead to personalized and less aggressive treatments.
biologie moléculaire; central nervous system; dna methylation; gene fusion; gène de fusion; molecular biology; méthylome; neuroepithelial tumor with patz1 fusion; système nerveux central; tumeur neuroépithéliale avec fusion patz1
09
Février
S0242-6498(24)00006-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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2. Carcinome papillaire de la thyroïde de sous type folliculaire, encapsulé, invasif.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341313
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00234-1
Guyétant S
10.1016/j.annpat.2023.12.006
2
101-105
44
09
Mars
S0242-6498(23)00234-1
publication avant impression
Accès restreint
article de périodique
humains
tumeurs de la thyroïde

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Hyperoxalurie primitive diagnostiquée sur biopsie ostéomédullaire : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341314
Sassi S
Derqaoui S
10.1016/j.annpat.2024.01.011
09
Février
S0242-6498(24)00036-1
publication avant impression
Accès restreint
article de périodique

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Intérêt d’une séance éducative « flash » coordonnée par des pharmaciens d’officine pour des patients âgés diabétiques de type 2 en milieu rural.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341320
Fougère E
Delavaud JM
Filloux C
Danigo A
Fagnère C
Jost J
Teissier MP
Demiot C
10.1016/j.therap.2024.01.003
The number of elderly people with type 2 diabetes (T2D) is increasing worldwide. Community pharmacies, thanks to their proximity, provide more easy access to therapeutic education for rural patients. Populations living in isolated areas require specific educational resources related to their condition. The aim of this project was to perform a short (FLASH) educational intervention, coordinated by community pharmacists, and then evaluate the impact of this intervention on patient knowledge of their disease. The study was performed in Issoudun, a rural French town of approximately 10,000 inhabitants. Educational priorities were defined and the project was presented to health authorities and local health professionals. Pharmacies in Issoudun recruited patients, either alone or accompanied by their caregivers. The educational intervention lasted 2h and focused on 4 teaching objectives: knowledge concerning diabetes, diabetic complications and how to monitor them; how to react to hypoglycemia; understanding treatments; and understanding glycated hemoglobin. The impact of this educational intervention was assessed using a questionnaire delivered before the intervention, immediately after, and after 6months. Forty-five patients aged 71 6years with T2D duration of 14 6years were recruited over 6months. Some false beliefs were identified before the intervention. The educational session led to a significant improvement in the percentage of correct answers (before: 60.3% 7.5, after: 99% 0.4, P 0.0002) and at 6months (99.5% 0.3, P 0.0002) compared with the patients' initial knowledge. Almost all false beliefs were corrected by the intervention and patients were able to recall the mechanism of action of their drugs, with the help of a key and lock schematic. This short FLASH educational intervention, coordinated by community pharmacists, showed that the model was both interesting to patients and effective. This method could be expanded to other rural communities and medical deserts.
community pharmacy; diabète de type 2; elderly patients; intervention éducative courte; milieu rural; patient âgé; pharmacien d’officine; rural area; short educational intervention; therapeutic patient education; type 2 diabetes; éducation thérapeutique du patient
23
Janvier
S0040-5957(24)00006-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Anomalie de connexion de l'artère coronaire droite au niveau de l'artère pulmonaire associée à une sténose du tronc commun gauche.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341990
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(24)00016-7
Ait Mokhtar O
Hamidouche K
Amini N
Boudjemline Y
Azzouz A
Benkhedda S
10.1016/j.ancard.2024.101737
We describe herein a case of a 16 years-old female patient referred to our department for further exploration of a chest pain. Color Doppler echocardiography revealed an abnormal flow at the level of the pulmonary artery. Exercise testing was abnormal leading to further imaging including computed cardiac tomography followed by coronary angiography which showed anomalous origin of the right coronary artery from the pulmonary artery (ARCAPA) associated with mid shaft left main stenosis. We discuss this uncommon association and therapeutic options.
2
101737
73
arcapa; anomalies de connexion des coronaires; cardiopathie congénitale; congenital heart disease; anomalous connections of coronary aerteries; arcapa; coronary stenosis; coronary reimplantation; réimplantation coronaire; sténose coronaire
10
Avril
S0003-3928(24)00016-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
humains
Femelle
adolescent
artère pulmonaire
anomalies congénitales des vaisseaux coronaires
anomalies congénitales des vaisseaux coronaires
tomodensitométrie
coronarographie
sténose coronarienne
sténose coronarienne

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Aerococcus viridans might not be the cause in this case.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38341991
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00064-1
Fernström N
Rasmussen M
10.1016/j.ancard.2023.101629
2
101629
73
10
Avril
S0003-3928(23)00064-1
publication avant impression
Accès restreint
lettre
humains
aerococcus

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Prévalence des ménorragies chez les femmes à La Réunion.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38342237
Battegay M
Khaled S
Reitz L
Balaya V
Theobald PV
Boukerrou M
Tran PL
10.1016/j.gofs.2024.02.002
AbstractText Label OBJECTIVES To estimate the prevalence of menorrhagia in women in Reunion Island using the Higham score, to evaluate self-reporting as an alternative diagnostic method, and to study women's level of knowledge about menorrhagia and its impact on their quality of life. /AbstractText AbstractText Label METHODS This was a descriptive, cross-sectional observational study involving 185 adult women with menstrual periods living in Reunion Island. Women volunteered to answer an online self questionnaire proposed by healthcare professionals from January to May 2023 in Reunion Island. They completed a general information questionnaire, the Higham score, a menorrhagia knowledge questionnaire and a menstrual quality of life questionnaire. /AbstractText AbstractText Label RESULTS The prevalence of menorrhagia in the sample was 48.1% using the Higham score and 46.5% using self-report. Women's level of knowledge about menorrhagia is still insufficient, given the significant impact on quality of life during menstruation among those suffering from this symptom. /AbstractText AbstractText Label CONCLUSION The prevalence of menorrhagia in our sample of women on Reunion Island is high. Measures need to be taken to break the taboos surrounding menstruation, promote menstrual education and foster a better understanding by women of menstrual pathologies, particularly menorrhagia. Early detection of this symptom would enable faster treatment and avoid complications and adverse effects on quality of life. /AbstractText
heavy menstrual bleeding; prevalence; higham score; reunion island
09
Février
S2468-7189(24)00041-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Les forums de discussion dédiés au cancer du sein peuvent-ils être utiles aux soignants? Analyse des messages initiaux du forum de la Ligue Nationale Contre le Cancer pendant une année.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38342238
Burgué H
Trensz P
Mathelin C
Schohn A
10.1016/j.gofs.2024.02.003
AbstractText Label OBJECTIVES forums are a source of health information and exchange. They can be studied to determine patients' needs and improve caregivers' practices. The aim of this study was to identify the needs of breast cancer patients based on messages posted on a discussion forum. /AbstractText AbstractText Label METHODS Initial messages posted in 2021 on the Ligue Nationale Contre le Cancer (LNCC) breast cancer forum were analyzed quantitatively. Message content was classified into three categories: testimonial, request for advice or request for medical opinion. The tone of the message (positive, neutral, or negative) was recorded. The temporality of the illness during which the patient expressed herself was defined. Analysis was carried out on the initial messages using the Chi2, Fisher, and Kruskal-Wallis tests, with a significance level of 0.05. /AbstractText AbstractText Label RESULTS In 2021, 640 initial messages posted on the LNCC forum dedicated to breast cancer were analyzed. Messages were posted by 312 authors, including 275 patients and 37 family members. Three main types of messages were identified: requests for medical advice (n 339), advice (n 164) and testimonials (n 137). Requests for medical advice elicited fewer responses than testimonials (p 0.001). A need for supportive care was identified in 42.8% of messages, mostly concerning social (17.3%) and psychological (13%) care. /AbstractText AbstractText Label CONCLUSION Our study revealed a need for more information especially regarding the social impact of the disease and the side-effects of treatment. The period of greatest need of information was the diagnostic waiting time. However, patients using discussion forums are not representative of all women with breast cancer and our results should not be generalized to all patients treated for breast cancer. /AbstractText
breast cancer; care pathway; forum; social support; support care
09
Février
S2468-7189(24)00042-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Comment Palmer faisait… Raoul Palmer et l’aventure de la coeliochirurgie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38342239
Madelenat P
Chene G
10.1016/j.gofs.2024.02.004
raoul palmer; endoscopy; history of medicine; laparoscopy; minimal invasive surgery
09
Février
S2468-7189(24)00043-6
publication avant impression
Accès restreint
article de périodique

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Synovialosarcome primitif du rein : si tout était déjà dans les urines pyéliques ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38342653
Da Silva F
Saada-Sebag G
Leer AM
Meilhac-Fournier C
Valmary-Degano S
Giovannini D
10.1016/j.annpat.2023.12.002
Synovialosarcoma is a malignant mesenchymal tumor of young adults that occurs in the deep soft tissues, particularly around large joints. When it occurs in more unusual sites, it could present a significant diagnostic challenge. In this case, a 19-year-old girl was treated for a pyloric mass. A pyelic urine cytology performed simultaneously with a pyloric biopsy proved to be a significant element of orientation and perfectly concordant with the histopathological aspect of the pyelic mass after nephrectomy. We report here the first case of renal synovialosarcoma documented in pyelic urine.
cell block; cellules rhabdoïdes; cytobloc; cytologie; cytology; primary renal synovial sarcoma; pyelic urine; renal sarcoma; ss18-ssx; sarcome rénal; synovialosarcome rénal primitif; urines pyéliques; rhabdoid cells
10
Février
S0242-6498(23)00230-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Les temps forts en dialyse en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38345207
Bataille S
Céline N
10.1684/ndt.2024.66
There has been a wealth of new developments in dialysis this year with the publication of several trials relating to dialysis technique, physical activity and the use of new dialysis treatments. Quality of life should be assessed and managed in all dialysis patients. Lowering the temperature of the dialysis bath in the MyTemp trial does not appear to have an effect on mortality and cardiovascular events. High volume convective hemodiafiltration currently represents the reference technique in hemodialysis; the Convince study confirms its superiority in terms of all-cause mortality. The DIATT study shows the benefit of the presence of an adapted physical activity professional to promote physical activity in dialysis patients and shows that it is necessary for this support to be reimbursed. The RENAL-AF and AXADIA-AFNET 8 studies lack power to conclude on the use of new oral anticoagulants in hemodialysis. For angiotensin receptor neprilysin inhibitors, studies are too weak to allow their use. SGLT2 inhibitors could be used in peritoneal dialysis to increase diuresis or delay the appearance of peritoneal fibrosis but to date only studies on models animals exist. Factor XI inhibitors are a new therapeutic class that could be used and would reduce the risk of thrombosis and hemorrhage. Increasingly, the feelings of patients and caregivers are more and more taken into account. Patient/caregiver communication must be at the heart of care. We will also be looking at the conservative treatment, the management of pruritus in hemodialysis and finally the care of patients with calciphylaxis.Les nouveautés en dialyse ont été riches cette année avec la publication de plusieurs essais touchant aussi bien à la technique de dialyse, à l’activité physique et à l’utilisation de nouveaux traitements en dialyse. La qualité de vie doit être évaluée et prise en charge chez tous les patients dialysés. La baisse de température du bain de dialyse dans l’essai MyTemp ne semble pas avoir d’effet sur la mortalité et les événements cardiovasculaires. L’hémodiafiltration haut volume convectif représente la technique de référence en hémodialyse dialyse actuellement : l’étude Convince confirme sa supériorité en termes de mortalité toute cause. L’étude DIATT montre l’intérêt de la présence d’un professionnel en activité physique adaptée pour favoriser l’activité physique chez les patients dialysés et montre qu’il est nécessaire que cette prise en charge soit remboursée. Les études RENAL-AF et AXADIA-AFNET 8 manquent de puissance pour conclure sur l’utilisation des nouveaux anticoagulants oraux en hémodialyse. Pour les angiontensin receptor neprilysin inhibitor, les études sont trop faibles pour permettre leur utilisation. Les inhibiteurs des cotransporteurs sodium-glucose de type 2 (iSGLT2) pourraient être utilisés en dialyse péritonéale pour augmenter la diurèse ou retarder l’apparition de la fibrose péritonéale mais, à ce jour, seules des études sur modèles animaux existent. Les inhibiteurs du facteur XI sont une nouvelle classe thérapeutique qui pourrait être utilisée et diminuerait le risque de thrombose et d’hémorragie. Le ressenti des patients et aidants est de plus en plus pris en compte. La communication patients/soignants doit être au cœur de la prise en charge. Seront abordés également le traitement conservateur, la prise en charge du prurit en hémodialyse et le soin des patients atteints de calciphylaxie.
S1
1-11
20
communication; hemodiafiltration; adapted physical activity; conservative treatment
12
Février
publication avant impression
Accès restreint
article de périodique
humains
dialyse rénale
qualité de vie
hémodiafiltration
défaillance rénale chronique
dialyse péritonéale

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Les temps forts en néphrologie en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38345208
Bobot M
Lemoine S
10.1684/ndt.2024.67
This article aims to summarize the “Quoi de neuf en néphrologie?” session held at the 2023 SFNDT Congress in Liège and sessions focused on updates regarding IgA nephropathy (NIgA) and ANCA-associated vasculitis. The agenda for the nephrology “Quoi de neuf en néphrologie?” session this year was to review key publications from non-nephrology journals, discussing topics such as nephroprotection, treatment of glomerulopathies (IgA and APOL1), clinical trials on arterial hypertension, urinary lithiasis, and other areas of renal physiology, including glomerular filtration rate estimation.Cet article a pour but de résumer d’une part la session « Quoi de neuf en néphrologie ? » qui a eu lieu au congrès de la Société francophone de néphrologie, dialyse et transplantation (SFNDT) 2023 à Liège en Belgique, mais également les sessions portant sur les actualités de la néphropathie à IgA (NIgA) et des vascularites associées aux anticorps anticytoplasme des polynucléaires neutrophiles (ANCA). Le cahier des charges du « Quoi de neuf en néphrologie ? » cette année était de reprendre les principaux articles publiés dans des revues hors néphrologie et s’est articulé sur les publications autour de la néphroprotection, du traitement des glomérulopathies (IgA et APOL1), des essais cliniques sur l’hypertension artérielle ou dans la lithiase urinaire, ou dans d’autres champs de la physiologie rénale comme l’estimation du débit de filtration glomérulaire.
s1
1-9
20
iga nephropathy; anca-associated vasculitis; nephroprotection; kidney physiology; clinical trials
12
Février
publication avant impression
Accès restreint
article de périodique
Protéine APOL1, humain
humains
néphrologie
glomérulonéphrite à dépôts d'IgA
Débit de filtration glomérulaire
urolithiase

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A rare case of upper septal fascicular ventricular tachycardia presented in a case report.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38354636
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(24)00017-9
Zaccaro L
Avondo S
Albani S
Scacciatella P
10.1016/j.ancard.2024.101738
AbstractText Label CASE SUMMARY A 71-year-old presented at the outpatient clinic with palpitations and NYHA II functional class. 12-lead ECG exhibited Upper septal idiopathic left ventricular tachycardia (US-ILVT). Ventricular tachycardia (VT) was interrupted with Verapamil administration, no further recurrences were documented after beta-blockers therapy was started. No coronary artery stenosis were detected. The US-ILVT was successfully treated by ablating the proximal site of the left anterior fascicle (LAF), where diastolic potential (P1) and pre-systolic potential (P2) with inverted sequence were detected during the electrophysiology study (EP) study. Cardiac magnetic resonance imaging (CMR) was performed with demonstration of intramyocardial late gadolinium enhancement (LGE) at the level of middle-basal portions of interventricular septum and basal portion of infero-lateral wall and no edema detection. A single catheter implantable cardioverter defibrillator (ICD) was implanted as secondary prevention. VT has never recurred during 3 months of follow-up with remote control of ICD. /AbstractText AbstractText Label DISCUSSION To the best of our knowledge, this is the first report in which US-ILVT was associated with ventricular septal LGE, suggestive of previous myocarditis, as substrate of re-entrant circuit. Scar-related ventricular tachycardia circuit is also suggested by the evidence of a premature ventricular complex (PVC) as trigger of recurrent VT in our case. /AbstractText
2
101738
73
ablation d'arytmies par cathéter; cardiac magnetic resonance; case report; catheter ablation; fait clinique; résonance magnétique cardiaque; tachycardie ventriculaire; ventricular tachycardia
13
Avril
S0003-3928(24)00017-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
produits de contraste
gadolinium
humains
sujet âgé
tachycardie ventriculaire
tachycardie ventriculaire
tachycardie ventriculaire
imagerie par résonance magnétique
cicatrice
ablation par cathéter

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Takotsubo syndrome : A cause of reversible microvascular coronary dysfunction.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38354637
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(24)00013-1
Zeitouni M
Procopi N
Redheuil A
Collet JP
10.1016/j.ancard.2024.101734
Since the first description of takotsubo syndrome 30 years ago, only a little is known on the underlying physiopathology leading to peculiar left ventricular function alteration and myocardial damage related to acute emotional or physical stress. In the present case, we used continuous invasive thermodilution to evaluate coronary microvascular function at the acute phase of takotsubo and after recovery. The acute phase of takotsubo was characterized by a reduced coronary output and altered reserved flow with persistently high resistance during hyperaemia. At 6 weeks, we described a complete recovery of microvascular function, concomitant to LVEF recovery.
2
101734
73
cardiopathie de stress; coronary physiology; physiologie coronaire; stress cardiopathy; takotsubo
13
Avril
S0003-3928(24)00013-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
humains
syndrome de tako-tsubo
fonction ventriculaire gauche
débit cardiaque

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Des taux élevés d’auto-anticorps anti-topo-isomérase-1 sont associés à l’extension de la fibrose cutanée et à la progression vasculaire chez les patients atteints de sclérodermie systémique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38355359
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01250-X
Dol C
Granel B
Resseguier N
Kaplanski G
Reynaud-Gaubert M
Schleinitz N
Grob JJ
Delaporte E
Lafforgue P
Rossi P
Bardin N
Benyamine A
10.1016/j.revmed.2023.11.006
AbstractText Label BACKGROUND Anti-centromere antibodies, anti-topoisomerase-1 antibodies (ATA), and anti-RNA-polymerase III antibodies are three Systemic Sclerosis (SSc)-specific autoantibodies. Their detection is helpful in determining the prognosis. We aimed to evaluate whether ATA levels were associated with disease severity at diagnosis or disease progression during follow-up in ATA positive patients. /AbstractText AbstractText Label METHODS We conducted a single-centre French retrospective observational study, between 2014 and 2021. ATA positive patients fulfilling the ACR/EULAR 2013 classification criteria for SSc with a minimal follow-up of 1 year and 2 ATA dosages were included. SSc patients with high IgG ATA levels at baseline ( 240IU/mL) were compared with SSc patients with low levels ( 240IU/mL), at inclusion and at 1 and 3 years. A variation of at least 30 % of ATA levels was considered significant. /AbstractText AbstractText Label RESULTS Fifty-nine SSc patients were included and analysed. There was a predominance of women and of patients with diffuse interstitial lung disease. Patients with high ATA levels exhibited a higher skin sclerosis assessed by the modified Rodnan skin score (P 0.0480). They had a lower carbon monoxide transfer coefficient (P 0.0457), a lower forced vital capacity (FVC) (P 0.0427) and more frequently had a FVC under 80 %, when compared to patients with low ATA levels (P 0.0423). Initial high ATA levels were associated with vascular progression at one year (21.95 % vs. 0 %; P 0.0495). /AbstractText AbstractText Label CONCLUSION ATA levels are associated with skin sclerosis and vascular progression in SSc. Beyond the detection of ATA, quantifying this autoantibody might be of interest in predicting disease severity and prognosis in SSc. /AbstractText
3
126-131
45
anti-scl70; anti-topoisomerase-1 antibody; anticorps anti-scl-70; anticorps anti-topoisomérase-1; autoantibody level.; disease progression; disease severity; gravité; progression; sclérodermie systémique; systemic sclerosis; taux d’auto-anticorps
13
Mars
S0248-8663(23)01250-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
étude d'observation
autoanticorps
humains
Femelle
Mâle
autoanticorps
sclérose
sclérodermie systémique
sclérodermie systémique
pronostic
fibrose

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Pathologie thyroïdienne : actualités et problèmes pratiques. Réponses au pré-test.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38355378
Guyétant S
Belleannée G
Decaussin-Petrucci M
10.1016/j.annpat.2024.01.003
13
Février
S0242-6498(24)00008-7
publication avant impression
Accès restreint
article de périodique

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Les tumeurs des glandes salivaires associées à des transcrits de fusion.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38355379
Laé M
Lanic MD
Lépine C
Hourseau M
Benzerdjeb N
Uro-Coste E
Costes-Martineau V
10.1016/j.annpat.2023.12.012
Salivary gland tumors represent a diagnostic challenge for pathologists due to their rarity, their very wide histopathological and immuno-phenotypic spectrum, and the recent identification of new entities. This article presents the main molecular characteristics of these tumors in order to allow any pathologist to perceive the diagnostic tracks of these ENT tumors and to better guide the molecular approach to establish the diagnosis and guide therapy.
fusion genes; gènes de fusion; ngs; salivary glands tumors; transcript; transcrits; ngs; tumeurs des glandes salivaires
13
Février
S0242-6498(24)00005-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Tumeurs nasosinusiennes à translocation.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38355380
Lépine C
Trinquet A
Laé M
Costes-Martineau V
10.1016/j.annpat.2023.12.013
In recent years, several nasal cavity and sinus entities have been described with fusion genes. Salivary gland tumors with fusion genes will not be discussed in this article, but it should be kept in mind that accessory salivary glands are present in the nasal cavity and sinuses and can therefore lead to tumoral lesions. Entities with specific or more frequently described rearrangements in the nasal cavities and sinuses are DEK::AFF2 squamous cell carcinomas,;non-intestinal and non-salivary nasosinusal adenocarcinomas, some of which displaying ETV6 gene rearrangements; biphenotypic nasosinusal sarcomas, most of which displaying PAX3 gene rearrangements; and Ewing's adamantinoma-like sarcomas, which display the same rearrangements as conventional Ewing's sarcomas, mainly the EWSR1::FLI1 rearrangement. Each entity will be described morphologically, immunohistochemically, and prognostically.
carcinoma; carcinome; fosses nasales; nasal cavity; rearrangement; réarrangement; sarcoma; sarcome; sinus
13
Février
S0242-6498(24)00007-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Étude CamiCon : évaluation d’un nouvel outil pour la réalisation d’un calendrier mictionnel automatisé et connecté.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38364362
Alameda F
Audenet F
Mandron E
Timsit MO
Fontaine E
Pietak M
Mejean A
Hurel S
10.1016/j.fjurol.2024.102582
AbstractText Label INTRODUCTION A voiding diary (VD) is a key element in the evaluation of patients with overactive bladder (OAB) at initial presentation and during treatment to assess its effectiveness. In order to be clinically relevant, it must be performed over 3 days according to the International Continence Society (ICS). Unfortunately, some patients find it cumbersome. We aimed to evaluate the reliability and patient satisfaction when using a connected tank device. /AbstractText AbstractText Label MATERIAL AND METHOD We conducted a single-center prospective study including 41 patients. Each patient completed a paper voiding diary and then a diary with Diary Pod (DP) or inversely depending on the study arm. Data from 34 patients were collected. After completion of both diaries, patients completed a satisfaction questionnaire sent by email via GoogleForm. Study statistics were performed with Jamovi and Excel software. /AbstractText AbstractText Label RESULT Data from 34 patients were analyzed. There was a statically significant difference (P 0.046) between the mean volume calculated from the paper VD and that calculated from the connected VD (DP). There was no statistically significant difference (P 0.112) between the mean number of daytime voids, mean number of nighttime voids (P 0.156), mean water intake (P 0.183) reported on the paper VD and the connected VD. Thirteen (42%) paper VD and 1 connected VD did not include documentation of the presence or absence of urine leakage or urgency. There was no statistically significant difference between the two calendars regarding the presence or absence of urine leakage (P 0.180) and urinary urgency (P 0.564). Eighty-four percent (26/31) preferred the connected tank to the usual method (paper/pen), while 55% (17/31) and 29% (9/31) of the participants respectively answered that the DP was very definitely or definitely an aid for performing VD. Nevertheless, 39% (12/31) and 55% (17/31) considered its price to be high or fair and only 22% (7/31) were inclined to buy it. /AbstractText AbstractText Label CONCLUSION This study showed that the Diary connected reservoir Pod is a reliable and innovative tool for voiding schedules. It facilitates data collection for the majority of patients (83%) and could, through better patient compliance, provide better quality data and help their interpretation by the physician. These factors could encourage the implementation of the connected voiding diary as a diagnostic tool. It would also be used for the assessment of treatment effectiveness in daily clinical practice as well as in research. Its cost remains a major obstacle, judged by 39% of patients to be too high, and could therefore be proposed in specific situations requiring precise data. /AbstractText
3
102582
34
dispositif d’enregistrement; dispositif médical; electronic diary; journal mictionnel; journal électronique; lower urinary tract symptoms; medical device; overactive bladder; recording device; symptômes des voies urinaires inférieures; vessie hyperactive; voiding diary
15
Février
S2950-3930(24)00037-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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« Les réunions de concertation pluridisciplinaire de pelvi-périnéologie modifient-elles les prises en charges thérapeutiques ? ».
2024
http://www.ncbi.nlm.nih.gov/pubmed/38367348
Delacroix C
Martis S
Allegre L
Fatton B
De Tayrac R
Wagner L
10.1016/j.fjurol.2024.102587
AbstractText Label INTRODUCTION Since the banning of trans-vaginal meshes for pelvic organ prolapse treatment by the FDA in 2019, French authorities have been gradually regulating the use of prosthetic materials in urogynecology. The decision to fit a mid-urethral sling or a reinforcement implant for the cure of prolapse, as well as the management of complex genital prolapse and serious post-implant complications, must be the subject of multidisciplinary consultation and a shared medical decision. To comply with these regulations, multidisciplinary team meetings (MDTMs) have been set up. The aim of the study was to evaluate the impact of these meetings on patient management. /AbstractText AbstractText Label MATERIAL We carried out a retrospective study in a tertiary hospital in France on all cases presented in MDTM of urogynecology over the year 2022. MDTMs were held weekly, with a Prosthesis MDTM focusing on slings, sacrocolpo/hysteropexies and prosthetic complications, lead by the urology team, and a Prolapse MDTM focusing on pelvic organ prolapse and complex prolapses, lead by the gynecology team. We compared the initial proposal of the patient's referring physician versus the final proposal of the MDTM. /AbstractText AbstractText Label RESULTS Three hundred and seventy-five cases were presented in our center in 2022: 188 in Prosthetic MDTM and 187 in Prolapse MDTM. The Prosthetic and Static MDTMs agreed with the initial proposal in 83 and 64% of cases respectively, while the therapeutic strategy was questioned in 12 and 36% of cases respectively. /AbstractText AbstractText Label CONCLUSION For almost a quarter (24%) of patients, the MDTM of urogynecology opted for a different management from that proposed by the referring physician. The presentation of cases to the MDTM is a legal obligation in specific indications. It also plays an educational role, enabling shared decision-making and responsibility, which is an asset in functional surgery. /AbstractText
3
102587
34
bandelette sous-urétrale; complications; incontinence urinaire; miduretral sling; multidisciplinary team meeting; pelvic organ prolapse; prolapsus; promontofixation; réunion de concertation pluridisciplinaire; sacrocolpo/hysteropexy; urinary incontinence
16
Février
S2950-3930(24)00042-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Évaluation de la pratique pharmaceutique en établissement de santé : une étude exploratoire comparant les processus en France et au Québec.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38367934
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00030-0
Marc M
Rambourg P
Bussières JF
10.1016/j.pharma.2024.02.010
AbstractText Label CONTEXT To ensure compliance with the legal and normative framework, the professional orders which supervise the practice of pharmacy have established a professional inspection process. In addition to this process, other external organizations also require an accreditation, authorization, certification or validation process for professional practices. /AbstractText AbstractText Label OBJECTIVE The main objective is to identify and compare the methods of evaluating pharmaceutical practice in hospitals in France and Quebec. /AbstractText AbstractText Label RESULTS In order to identify and compare the methods of evaluating pharmaceutical practice in hospitals in France and Quebec, our approach allowed us to identify more organizations in France (i.e. High Authority of Health, regional health agencies, the National Order of Pharmacists, the Nuclear Safety Agency, the Biomedicine Agency and the National Agency for the Safety of Medicines and Health Products) than in Quebec (i.e. Accreditation Canada, Ordre des pharmaciens du Québec and Health Canada). The study highlights the legal framework and applicable standards, the surveyors, the evaluation methods and the particularities for the evaluation of the hospital, the pharmacy department and the members of the department. /AbstractText AbstractText Label CONCLUSIONS This study highlights the evaluation processes of pharmaceutical practice in hospitals. In France as in Quebec, we recognize the importance of the drug circuit in the hospital, the development and operation of a pharmacy department and the practice of pharmacy. While there are more similarities for the assessment of the drug circuit in hospitals and pharmacy department, important differences are observed for the assessment of individuals. We believe that the publication of a comparative analysis can contribute to discussions and exchanges to benefit from the best practices of each country. /AbstractText
3
560-574
82
professional inspection; accreditation; approval; audit; authorization; certification; evaluation of professional practices; hospital pharmacist
15
Mai
S0003-4509(24)00030-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
préparations pharmaceutiques
humains
Québec
pharmacie d'hôpital
hôpitaux
pharmacie
pharmaciens
France

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Mise en place d’un système de planification et d’ordonnancement avancé dans un contexte pharmaceutique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38367935
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00027-0
Belghith M
Bouajaja S
10.1016/j.pharma.2024.02.007
Optimizing its supply chain has now become more than a necessity for any company seeking to expand its national and international market, so that it is able to continue its progress and fulfil its obligations towards its employees and its customers, particularly in the pharmaceutical context. The Covid-19 pandemic has shown the importance of resilience in the pharmaceutical industry to deal with unexpected disruptions and high demand from patients and authorities. Better production planning based on data management and predictive analysis, through the use of new Industry 4.0 tools, improves operational performance in terms of productivity and flexibility in relation to the vagaries of the request. It is in this vision that we approach the implementation of an Advanced Planning and Scheduling -APS system, in a pharmaceutical laboratory. It is a leading company in the Tunisian pharmaceutical market that seeks to expand its national and international market. In this work, we describe its project to implement an Advanced Planning and Scheduling system and its integration with its already functional Enterprise Resource Planning software system, as complementary decision-making tools.
3
584-595
82
digitalisation; digitalization; industrie pharmaceutique; pharmaceutical industry; planification et ordonnancement; planning and scheduling
15
Mai
S0003-4509(24)00027-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
préparations pharmaceutiques
humains
pandémies
pharmacie
industrie pharmaceutique

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Traumatologie lacrymale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38368761
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00021-4
Ducasse A
Larré I
10.1016/j.jfo.2024.104076
Among lacrimal system injuries, canalicular lacerations are at the top of the list. Men are more affected than women, but children are most likely to experience such trauma. The cause depends on the patient's age: in young children, there is a higher prevalence of animal bites (dogs and cats); in young adults, fights predominate, since motor vehicle accidents have become less common; in the elderly, falls are among the most frequent causes. Tetanus vaccination is required in all cases, but assessment for rabies exposure is necessary in the case of dog or cat bites. Diagnosis is very simple: it is based on examination or wound probing. Other head, facial, or ocular injuries must be excluded; for example, an injury to the globe must take precedence over a canalicular laceration. In the absence of an ocular injury, the canalicular wound should be managed surgically within 48hours under an operating microscope: identification of both severed ends of the injured canaliculus, suture of the severed canaliculus with monofilament suture, and appropriate lacrimal intubation if indicated. Other trauma to the lacrimal system, such as sharp or blunt trauma to the lacrimal sac or nasolacrimal duct, are much rarer.
3
104076
47
canalicular laceration; intubation monocanaliculaire; lacrimal sac laceration; lacrimal system trauma; monocanalicular intubation; nasolacrimal duct injury.; plaie du canalicule; plaie du conduit lacrymonasal; plaie du sac lacrymal; traumatologie lacrymale
17
Mars
S0181-5512(24)00021-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
enfant
sujet âgé
Mâle
jeune adulte
Femelle
humains
animaux
chats
chiens
enfant d'âge préscolaire
maladies des chats
maladies des chiens
appareil lacrymal
lésions traumatiques de l'oeil
lésions traumatiques de l'oeil
lésions traumatiques de l'oeil
lacérations
lacérations
lacérations

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Enquête de qualité de vie auprès de 3738 patients traités par injections intravitréennes pour leur dégénérescence maculaire liée à l’âge.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38368762
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00020-2
Uzzan J
Haddad M
Salamé N
10.1016/j.jfo.2024.104075
AbstractText Label PURPOSE To evaluate the peri- and post-intravitreal injection (IVI) symptoms reported by patients who have been repeatedly injected for age-related macular degeneration (AMD) and to analyze these according to the protocols of the injector. /AbstractText AbstractText Label MATERIALS AND METHODS Multi-center, cross-sectional, consecutive, analytical survey. /AbstractText AbstractText Label RESULTS The IVI protocols of 106 injectors differed in terms of the number of instillations of povidone-iodine, its contact time, and rinsing of the ocular surface post-injection. In total, 3,738 patients responded to the survey, 60.1% of whom were women; 36.4% had received more than 20 IVIs; 50.7% of patients reported irritation upon application of povidone-iodine. Post-IVI, depending on the symptom in question, between 44.8% and 57.4% of patients reported symptoms of ocular surface change. The number of instillations of povidone-iodine, its contact time with the ocular surface, and abundant rinsing post-IVI increased the immediate symptoms. Patients who received more IVIs were more prone to experiencing gritty eyes, and the incidence of acute pain increased in patients who had previously received over 20 IVIs. Women and patients previously treated for dry eye or glaucoma were at greater risk of worse symptoms. /AbstractText AbstractText Label CONCLUSION Comparing injecting centers' practices with patients' self-assessments showed an aggravation of symptoms of ocular surface changes related to povidone-iodine. This survey contributes to providing data for the implementation of a protocol to improve the quality of life of patients injected repeatedly for AMD. /AbstractText
3
104075
47
age-related macular degeneration; dégénérescence maculaire liée à l’âge; enquête; injections intravitréennes; intravitreal injections; ocular surface; proms; povidone iodine; povidone iodée; quality of life; qualité de vie; surface oculaire; survey
17
Mars
S0181-5512(24)00020-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
povidone iodée
humains
Femelle
Mâle
injections intravitréennes
qualité de vie
études transversales
povidone iodée
dégénérescence maculaire
dégénérescence maculaire

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L’électroconvulsivothérapie chez les médecins tunisiens : les controverses et les insuffisances.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38369427
Samaâli S
Lansari R
Hamdoun J
Larnaout A
Melki W
10.1016/j.encep.2023.12.001
connaissance; electroconvulsive therapy; enseignement; ethics; knowledge; perception; teaching; électroconvulsivothérapie; éthique
17
Février
S0013-7006(24)00021-6
publication avant impression
Accès restreint
article de périodique

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Mortalité maternelle par pathologies cardiovasculaires en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373486
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00052-7
Bruyère M
Morau E
Verspyck E
pour le Comité National d’Experts sur la Mortalité Maternelle
10.1016/j.gofs.2024.02.012
Between 2016 and 2018, cardiovascular diseases were responsible for 41 deaths, making it the leading cause of maternal death within 42 days postpartum in France. The maternal mortality ratio (MMR) for cardiovascular disease is 1.8 per 100,000 NV, a non-significant increase compared with the 2013-2015 triennium (MMR of 1.5 per 100,000 NV). Deaths from cardiac causes accounted for the majority (n 28), with 26 deaths secondary to cardiac disease aggravated by pregnancy (indirect deaths) and 2 deaths related to peripartum cardiomyopathy (direct deaths). Deaths from vascular causes (n 13) corresponded to 9 aortic dissections and 4 ruptures of large vessels, including 3 ruptures of the splenic artery. Preventability of death (possible or probable) was found in 56% of cases compared with 66% in the previous triennium. Care was considered sub-optimal in 57% of cases, down from 72% in the 2013-2015 triennium. In women with known cardiovascular disease, the areas for improvement concern multidisciplinary follow-up, repeated assessment of the cardiovascular risk (WHO grade) and early referral to an expert centre (expert cardiologists, obstetricians, anaesthetists and intensive care). In all pregnant women or women who have recently given birth, a cardiovascular etiology should be considered in the presence of suggestive symptoms (dyspnea, chest or abdominal pain). Ultrasound point of care examination (fluid effusions, cardiac dysfunction) and cardiac enzymes assay can help in the diagnosis. Finally, the woman must be involved in her own care.
4
221-230
52
cardiovascular disease; interdisciplinary communication aneurysm splenic artery aortic dissection; maternal mortality; quality of care
17
Avril
S2468-7189(24)00052-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
Femelle
grossesse
humains
mortalité maternelle
maladies cardiovasculaires
décès maternel
période du postpartum
France

---
Mortalité maternelle par hémorragie obstétricale en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373487
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00055-2
Verspyck E
Morau E
Chiesa-Dubruille C
Bonnin M
pour le Comité National d’Experts sur la Mortalité Maternelle
10.1016/j.gofs.2024.02.016
Between 2016 and 2018, 20 maternal deaths were related to obstetric haemorrhage, excluding haemorrhage in the first trimester of pregnancy, representing a mortality ratio of 0.87 per 100,000 live births (95% CI 0.5 -1.3). Obstetric haemorrhage is the cause of 7.4% of all maternal deaths up to 1 year, 10% of maternal deaths within 42 days, and 21% of deaths directly related to pregnancy (direct causes). Between 2001 and 2018, maternal mortality from obstetric haemorrhage has been considerably reduced, from 2.2 deaths per 100,000 live births in 2001-2003 to 0.87 in the period presented here. Nevertheless, obstetric haemorrhage is still one of the main direct causes of maternal death, and remains the cause with the highest proportion of deaths considered probably (53%) or possibly (42%) preventable according to the CNEMM's collegial assessment (see chapter 3). The preventable factors reported are related to inadequate content of care in 94% of cases and/or organisation of care in 44% of cases. In this triennium, maternal death due to haemorrhage occurred mainly in the context of caesarean delivery (65% of cases, i.e. 13/20), and mostly in the context of emergency care (12/13). The main causes of obstetric haemorrhage were uterine rupture (6/20) in unscarred uterus or in association with placenta accreta, and surgical injury during the caesarean delivery (5/20). Every maternity hospital, whatever its resources and/or technical facilities, must be able to plan any obstetric haemorrhage situation that threatens the mother's vital prognosis. Intraperitoneal occult haemorrhage following caesarean section and uterine rupture require immediate surgery with the help of skilled surgeon resources with early and appropriate administration of blood products.
4
238-245
52
caesarean; césarienne; haemorrhage; hémorragie; maternal death; mort maternelle; quality of care; qualité des soins; rupture utérine; uterine rupture
17
Avril
S2468-7189(24)00055-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
mortalité maternelle
décès maternel
césarienne
hémorragie de la délivrance
rupture utérine

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Mortalité maternelle et prise en charge par les services d’urgence en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373488
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00047-3
Rossignol M
Verspyck E
Jonard M
10.1016/j.gofs.2024.02.008
In France, 272 maternal deaths occurred during the period 2016-2018, of which 131 were initially treated by healthcare professionals not specialized in obstetric. Fifty-six files were excluded because they did not concern emergency services or because there was insufficient data to allow analysis. Seventy-five cases of maternal deaths initially treated by emergency services (in-hospital emergency department (ED) or emergency medical ambulance (SAMU)) were analyzed. Fifty-six cases were treated by the SAMU and 22 by an ED (both in 3 cases). The causes of death were 20 cardiovascular events, 18 pulmonary embolisms, 9 neurological failures and 8 hemorrhagic shocks. The event occurred during pregnancy in 48 cases (64%) and during per or postpartum period in 27 cases (36%). The motivations for consultation at the ED were mainly pain (n 9), respiratory distress (n 6) or faintness (n 3). The reasons for calling emergency dispatching service (SAMU) were cardiorespiratory arrest in 32 cases (57%) and neurological failure (coma or status epilepticus) in 6 cases (11%). Among the 56 patients treated outside the hospital, 17 died on scene and 39 were transported to a resuscitation room (n 13), a specialized department (n 13), an obstetrics department (n 8) and less often in the ED (n 2). This was considered appropriate in 35 out of 39 cases (90%). Concerning the 75 files analyzed (ED and SAMU), death was considered unavoidable in 37 cases (49%) and potentially avoidable in 29 cases (38%) (maybe 23, probably 6). Avoidability could not be established in 9 cases. Among the 29 potentially avoidable deaths (38%), one of the criteria of avoidability concerned emergency services in 14 cases (ED 9, SAMU/SMUR 5, 18% of the files studied). ED's cares were considered optimal in 11 cases (50%) and non-optimal in 11 cases (50%). SAMU's cares were considered optimal in 45 cases (80%).
4
288-295
52
arrêt cardiaque; cardiac arrest; cardiopulmonary arrest; emergency medical assistance system; emergency department; emergency medicine; maternal mortality; mobile emergency and resuscitation services; mortalité maternelle; médecine d’urgence; samu; smur; service d’accueil des urgences
17
Avril
S2468-7189(24)00047-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
décès maternel
services des urgences médicales
service hospitalier d'urgences
hôpitaux
France

---
Mortalité maternelle par accident vasculaire cérébral en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373489
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00059-X
Lepercq J
Rossignol M
Jonard M
pour le Comité National d’Experts sur la Mortalité Maternelle
10.1016/j.gofs.2024.02.019
Between 2016 and 2018, twenty maternal deaths were associated with a stroke. The 20 deaths whose main cause was stroke represent 7.4% of all maternal deaths, i.e. a maternal mortality ratio (MMR) of 0.9 per 100,000 live births(95% CI 0, 6-1,3). Among the 20 stroke deaths, it was hemorrhagic in 17 cases (85%), ischemic in 2 cases, and due to thrombophlebitis in 1 case. Stroke occurred during pregnancy in 8 women (40%) - one case before 12 weeks, 3 cases between 28 and 32 weeks, and 4 cases between 34 and 40 weeks; in 3 cases the stroke occurred intrapartum, and for the other 9 cases (45%) the stroke occurred postpartum between Day 1 and Day 15. Care was assessed as non-optimal in 10/19 (56%) of cases but mortality as possibly avoidable in 24% of cases (4/17 cases with conclusion established by the CNEMM) and not established in two cases. The potentially improvable elements identified were a delay in carrying out initial brain imaging in three cases (one case antepartum, two cases postpartum) and insufficient hemodynamic monitoring in intensive care in one case.
4
259-262
52
accident vasculaire cérébral hémorragique; hemorragic stroke; accident vasculaire cérébral ischémique; grossesse; ischemic stroke; maternal mortality; mortalité maternelle; pregnancy
17
Avril
S2468-7189(24)00059-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
mortalité maternelle
décès maternel
période du postpartum
accident vasculaire cérébral
France

---
Mortalité maternelle et organisation des soins en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373490
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00048-5
Morau E
Lejeune-Saada V
Chiesa-Dubruille C
Deneux-Tharaux C
10.1016/j.gofs.2024.02.009
Organization of care is a factor which is considered in addition to the content of care when assessing mortality cases. The factors related to the organization of care concern the suitability of the place of care, the completion of a necessary transfer, the adequacy of human and material resources, and the communication between caregivers. For the 2016-2018 triennium these preventability factors are the subject of a dedicated chapter. Overall, one or more preventability factors linked to the organization of care were reported in 51 cases, i.e. 24% of all assessed cases. The field of communication was the most frequently reported (32/51), followed by inappropriate place of care (20/51), insufficient human resources (13/51), transfers not performed or performed late (11/51) and insufficient material resources (9/51). An overall analysis can be made along two dimensions: organization within the maternity unit, and coordination with other sectors or outpatient medicine. Areas for improvement within the maternity unit relate to the ability to deal with life-threatening emergencies, to organize the call for specialized and/or trained human reinforcements, to organize intensive monitoring of patients in the event of organ failure, and to facilitate good communication between caregivers. Regarding coordination with other units, it is proposed to improve collaboration between the maternity unit's emergency department and the general emergency department, and to improve the transfer of information required by all those involved, including primary care physicians, in the pre-, per- and post-partum period. Finally, the place of care for patients presenting with a psychiatric and somatic pathology is a situation that requires careful consultation.
4
280-287
52
patient care management; communication interdisciplinaire; health workforce; interdisciplinary communication; maternal mortality; mortalité maternelle; organisation des soins; quality of health care; qualité des soins; ressources humaines
17
Avril
S2468-7189(24)00048-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
grossesse
Femelle
mortalité maternelle
prestations des soins de santé
France

---
Mortalité maternelle de causes indirectes (hors AVC, maladies cardiovasculaires et infections) en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373491
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00056-4
Guern VL
Rossignol M
Lepercq J
pour le Comité National d’Experts sur la Mortalité Maternelle
10.1016/j.gofs.2024.02.013
Maternal deaths from indirect obstetric causes result from a pre-existing condition or a condition that occurred during pregnancy without obstetric causes but was aggravated by the physiological effects of pregnancy. Twenty-nine deaths with an indirect cause related to a pre-existing condition, excluding circulatory diseases or infections, were analysed by the expert committee. Pre-pregnancy pathology was documented in 16 women (epilepsy, n 7; amyloid angiopathy, n 1; Dandy Walker syndrome, n 1; autoimmune diseases, n 3; diffuse infiltrative pneumonitis, n 1; thrombotic thrombocytopenic purpura, n 1; ovarian cancer in fragile X, n 1; major sickle cell disease, n 1). In 13 women, the pathology was unknown before pregnancy (breast cancer, n 9, epilepsy diagnosed during pregnancy, n 1, brain tumours, n 2 meningioma type, macrophagic activation syndrome, n 1). Death was associated with neoplastic or tumour pathology in 13 women (45%). At the same time, epilepsy was responsible for the death of 8 women (27%), making it the most common cause of death. For both neoplasia and epilepsy, about 50% of deaths were preventable, mainly due to undiagnosed and/or delayed treatment in the case of cancer and failure to monitor or adjust treatment in the case of epilepsy. Pre-conception counselling is therefore strongly recommended if a woman has a known chronic medical condition prior to pregnancy. Finally, if there is a family history of breast cancer, a breast examination is strongly recommended from the first visit during pregnancy, and any breast lumps should be investigated as soon as possible to avoid delaying appropriate treatment.
4
268-272
52
breast cancer; cancer du sein; chronic diseases; consultation préconceptionnelle; epilepsie; epilepsy; maladies chroniques; maternal mortality; mortalité maternelle; preconception consultation
17
Avril
S2468-7189(24)00056-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
décès maternel
maladies cardiovasculaires
mortalité maternelle
accident vasculaire cérébral
France
épilepsie
tumeurs du sein

---
Mortalité maternelle en France, 2016–2018, fréquence, causes et profil des femmes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373492
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00050-3
Saucedo M
Deneux-Tharaux C
Pour le Comité National d’Experts sur les Mort Maternelles
10.1016/j.gofs.2024.02.020
AbstractText Label OBJECTIVE To describe, for the 2016-2018 period, the frequency, causes and risk factors of maternal deaths in France. /AbstractText AbstractText Label METHOD cause of MM up to one year (7%) and 4th cause of MM up to 42 days. /AbstractText AbstractText Label CONCLUSION The overall national maternal mortality ratio does not show a downward trend, even with constant surveillance method. Territorial inequalities persist but change in their magnitude and in the regions concerned. The profile of the causes of maternal mortality up to one year of the pregnancy end shows the leading role of suicides and cardiovascular diseases, which illustrates that the health of pregnant women or those who have recently given birth is not limited to the obstetric domain, and highlights the importance of multidisciplinarity in the management and organization of care for women in this period. /AbstractText
4
185-200
52
france; maternal mortality; audit; confidential enquiry; enquête confidentielle; epidemiology; facteurs de risque; frequency; fréquence; maternal health; mortalité maternelle; risk factors; santé maternelle; surveillance épidémiologique
17
Avril
S2468-7189(24)00050-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
Femelle
humains
grossesse
adulte
adulte d'âge moyen
mortalité maternelle
décès maternel
maladies cardiovasculaires
cause de décès
suicide
France

---
Enquête Nationale Confidentielle sur les Morts Maternelles en France, un système de surveillance améliorée depuis 25 ans, indispensable pour la caractérisation fiable des décès maternels.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373493
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00049-7
Deneux-Tharaux C
Saucedo M
Pour le CNEMM
10.1016/j.gofs.2024.02.010
Although maternal mortality is rare in wealthy countries, it remains a fundamental indicator of maternal health. It is considered to be a sentinel event, the occurrence of which indicates dysfunctions, often cumulative, in the healthcare system. In addition to the classic epidemiological surveillance findings - number of deaths, maternal mortality ratio, distribution of medical causes, sub-groups of women at risk - its study, through a precise analysis of the history of each woman who died, enables to highlight areas for improvement in the content or organisation of care, the correction of which will make it possible to prevent not only deaths but also upstream morbid events involving the same mechanisms. To achieve this dual epidemiological and clinical audit objective, an ad hoc 'enhanced' system is needed. France has had such a system since 1996, the Enquête Nationale Confidentielle sur la Mortalité Maternelle (ENCMM), under the joint supervision of Santé Publique France and Inserm. The ENCMM method aims to identify maternal deaths exhaustively and reliably up to 1 year after the end of pregnancy, and to document each death as fully as possible. The 1st step is the multi-source identification (direct declaration, death certificates, linkage with birth certificates, hospital stay database) of women who died during pregnancy or in the year following its end. The 2nd step is the collection of detailed information for each death by a pair of clinical assessors. The 3rd step is the review of these anonymised documents by the National Expert Committee on Maternal Mortality, which establishes the maternal nature of the death (causal link with pregnancy) and, with a stated aim of improvement rather than judgement, assesses the adequacy of care and the preventability of the death. The summary of the information gathered for maternal deaths in the 2016-2018 period is presented in the other articles of this special issue.
4
178-184
52
audit; confidential enquiry; dispositif amélioré; enhanced system; enquête confidentielle; maternal mortality; mortalité maternelle; surveillance
17
Avril
S2468-7189(24)00049-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
décès maternel
décès maternel
mortalité maternelle
audit clinique
prestations des soins de santé
France

---
Mortalité maternelle par embolie amniotique en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373494
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00054-0
Morau E
Grossetti E
Bonnin M
pour le Comité National d’Experts sur la Mortalité Maternelle
10.1016/j.gofs.2024.02.015
Amniotic embolism remains the 3rd leading cause of maternal death in France, with 21 maternal deaths over the 2016-2018 triennium. The women who died were more likely to be obese (25%), to benefit from induction of labor (71%) and be cared in a maternity hospital 1500 deliveries/year (45%), compared with the reference population (ENP 2016). The symptom occurred mainly during labor (95%) and the course was rapid, with a symptom-to-fatality interval of 4 hours 45 minutes (min: 25 minutes - max: 8 days). Preventability was proposed for 35% of the deaths assessed, with areas for improvement identified in terms of technical skills (haemostasis procedures, management of polytransfusion), non-technical skills (communication) and health care organization (human resources, vital emergency plan, wide access to PSL). An autopsy was performed in 38% of deaths.
4
231-237
52
embolie amniotique; amniotic fluid embolism; arrêt cardiaque; cardiac arrest; haemorrhage; hémorragie; maternal death; mortalité maternelle; quality of health care; qualité des soins
17
Avril
S2468-7189(24)00054-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
embolie amniotique
mortalité maternelle
décès maternel
travail obstétrical
France

---
Mortalité maternelle chez les femmes avec vulnérabilité sociale en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373495
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00057-6
Grossetti É
Tessier V
Gomes E
pour le Comité National d’Experts sur la Mortalité Maternelle
10.1016/j.gofs.2024.02.017
Social vulnerability is a known factor in perinatal medical risk, both for the foetus and the mother. As part of the French confidential enquiry into maternal deaths, the introduction in 2015 of specific items relating to social status has made it possible to recreate this composite variable. Over the period 2016-2018, one woman in three who died was in a situation of social vulnerability. Of these 79 deaths, 32 (41%) were related to direct obstetric causes, 26 (33%) to indirect obstetric causes, 12 (15%) to suicides and 8 (10%) of unknown cause. Care was considered sub-optimal in 73% of cases, compared with 64% in the group of maternal deaths with no identified social vulnerability. 43 deaths were judged to be probably (n 12) or possibly (n 31) avoidable, 25 were not avoidable, and 11 were not sufficiently documented for this assessment; i.e. a proportion of 63% of probable or possible avoidability, a higher proportion compared with the 56% of avoidability among women with no identified social vulnerability. In 1/3 of maternal deaths, a lack of interaction between the woman and the healthcare system was involved in the chain of events leading to death, i.e. 2 times more than in the case of socially non-vulnerable women. Improving the interaction of women in socially vulnerable situations with the hospital system and the institutional and voluntary networks providing care, support and assistance is a priority. A specific, responsive medical and social organisation could contribute to this.
4
273-279
52
care pathway; domestic violence; interaction; maternal mortality; mortalité maternelle; parcours de soin; social vulnerability; violences intrafamiliales; vulnérabilité sociale
17
Avril
S2468-7189(24)00057-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
mortalité maternelle
décès maternel
suicide
France
facteurs de risque

---
Mortalité maternelle par complications hypertensives en France, 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373496
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00058-8
Dreyfus M
Rigouzzo A
Jonard M
10.1016/j.gofs.2024.02.018
Between 2016 and 2018, 13 maternal deaths were due to hypertensive disorders. During this period, the maternal mortality ratio was 0.6/100 000 live births. Hypertensive disorders were responsible for 4.8 % of maternal deaths during the first year, 5.1 % up to 42 days postpartum and for 13.5 % of direct maternal mortality. Maternal deaths due to hypertensive disorders increased close to signification (p 0.09) compared to the last triennium (MMR 0.2/100.000). Classification of the hypertensive disorders was : 5 severe preeclampsia, 3 eclampsia, 4 HELLP syndromes et 1 undefined hypertension. In five cases, a stroke was associated. Mode of delivery was a cesarean section when the hypertensive disorder started before the labour (8/13, 62%). Six women were older than 35 years old and 5/12 were nulliparous. Among the 12 cases where place of birth was known, 5 were born foreigners. Une obésité était présente dans 46% des cas. BMI was over 30 for 46%. Medical care were estimated non optimal in 11/13 of the cases. Among these deaths, 66 % (8/12) seemed to be preventable versus 82 % for the last period 2013-2015. The main causal factor of suboptimal management was unappropriate management by the obstetrical or anesthetist/intensive care squads, respectively: 3 lack of diagnosis, 8 delays for diagnosis and 5 underestimated severity. Four cases corresponded to unappropriated health care organization. Ceci confirme que les complications hypertensives de la grossesse ont un pourcentage d'évitabilité élevé ce qui laisse une grande marge d'amélioration dans leur prise en charge. This study offers the opportunity to stress major points to optimize medical management and health care organization facing hypertensive disorders during pregnancy.
4
263-267
52
hellp syndrome; eclamspia; gestational hypertension; grossesse; hypertension gravidique; maternal death; mort maternelle; preeclampsia; preeclampsie; pregnancy; éclampsie
17
Avril
S2468-7189(24)00058-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
mortalité maternelle
Hypertension artérielle gravidique
décès maternel
césarienne
Pré-éclampsie

---
Mortalité maternelle par thromboembolie veineuse en France 2016–2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373497
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00046-1
Jonard M
Rossignol M
Chiesa-Dubruille C
pour le Comité National d’Experts sur la Mortalité Maternelle
10.1016/j.gofs.2024.02.007
Pregnancy and the postpartum period represent a thromboembolic risk situation, with pulmonary embolism (PE) remaining one of the leading causes of direct maternal deaths in developed countries. Between 2016 and 2018 in France, twenty maternal deaths were caused by venous thromboembolic complications (VTE), yielding a Maternal Mortality Ratio (MMR) of 0.9 per 100,000 live births (95% CI 0.6-1.3), with no change compared to the periods 2013-2015 or 2010-2012. Among these 20 deaths, 1 death was related to cerebral thrombophlebitis, and the remaining 19 were due to PE. Regarding the timing of death, 2 deaths occurred after an early termination of pregnancy, 40% (8/20) during an ongoing pregnancy, and 50% (10/20) in the postpartum period. Among the 20 VTE deaths, 20% (4/20) occurred outside of a healthcare facility (at home or in a public place). Among the nineteen cases with documented BMI, seven women had obesity (37%), three times more than in the population of parturients in France (11.8%, ENP 2016). Among the nineteen PE deaths and the case of cerebral thrombophlebitis, eleven were considered preventable, six possibly preventable (35%), two probably preventable (12%), and three preventability undetermined. The identified preventability factors were inadequate care and the patient's failure to interact with the healthcare system. From the case analysis, areas for improvement were identified, including insufficient consideration of major and minor risk factors, the early initiation of appropriate prophylactic treatment, and the absence of fibrinolysis in cases of s refractory cardiac arrest due to suspected PE.
4
246-251
52
arrêt cardiaque maternel; embolie pulmonaire; grossesse; maternal cardiac arrest; maternal mortality; mortalité maternelle; pregnancy; pulmonary embolism; thrombose veineuse profonde; venous thromboembolism
17
Avril
S2468-7189(24)00046-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
mortalité maternelle
décès maternel
décès maternel
thromboembolisme veineux
thromboembolisme veineux
embolie pulmonaire
France
thrombophlébite

---
En aparté – entretien avec le Dr Camille Boulagnon-Rombi.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38373869
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00039-7
Rousseau A
10.1016/j.annpat.2024.01.014
2
88-89
44
18
Mars
S0242-6498(24)00039-7
publication avant impression
Accès restreint
éditorial

---
Cerclage par indentation sclérale chez un patient myope fort.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38377840
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00562-4
Martiano D
Massonnet S
Butori P
10.1016/j.jfo.2023.104030
3
104030
47
19
Mars
S0181-5512(23)00562-4
publication avant impression
Accès restreint
article de périodique
humains
myopie
myopie
myopie
indentation sclérale

---
Une tumeur conjonctivale atypique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38377843
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00583-1
Fitoussi R
Attia R
Stolowy N
David T
10.1016/j.jfo.2023.104051
3
104051
47
19
Mars
S0181-5512(23)00583-1
publication avant impression
Accès restreint
article de périodique
humains
tumeurs de la conjonctive

---
Malformation artérioveineuse rétinienne dans le cadre du syndrome de Bonnet-Dechaume-Blanc.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38377877
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00033-0
Blin J
Marks C
Drumare I
Smirnov V
10.1016/j.jfo.2024.104088
4
104088
47
19
Avril
S0181-5512(24)00033-0
publication avant impression
Accès restreint
article de périodique
Syndrome de Wyburn-Mason
humains
fistule artérioveineuse
fistule artérioveineuse
hémangiome
syndromes neurocutanés
syndromes neurocutanés
vaisseaux rétiniens
artère centrale de la rétine
artère centrale de la rétine

---
Les actualités en génétique oncologique mammaire pour la population féminine et masculine.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190969
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00002-3
Taris N
Luporsi E
Osada M
Thiblet M
Mathelin C
10.1016/j.gofs.2023.12.007
AbstractText Label OBJECTIVES Breast oncology genetics emerged almost 30 years ago with the discovery of the BRCA1 and BRCA2 genes. The evolution of analytical practices has progressively allowed access to tests whose results now have a considerable impact on the management of both female and male breast cancers.The Sénologie Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF) asked five specialists in breast surgery, oncology and oncological genetics to draw up a summary of the oncogenetic testing criteria used and the clinical implications for the female and male population of the test results, with or without an identified causal variant. In the case of proven genetic risk, surveillance, risk-reduction strategies, and the specificities of surgical and medical management (with PARP inhibitors in particular) were updated. /AbstractText AbstractText Label METHODS This summary was based on national and international guidelines on the monitoring and therapeutic management of genetic risk, and a recent review of the literature covering the last five years. /AbstractText AbstractText Label RESULTS Despite successive technical developments, the probability of identifying a causal variant in a situation suggestive of a predisposition to breast and ovarian cancer remains around 10% in France. The risk of breast cancer in women with a causal variant of the BRCA1, BRCA2, PALB2, TP53, CDH1 and PTEN genes is estimated at between 35% and 85% at age 70. The presence of a causal variant in one of these genes is the subject of different recommendations for men and women, concerning both surveillance, the age of onset and imaging modalities of which vary according to the genes involved, and risk-reduction surgery, which is possible for women as soon as their risk level exceeds 30% and remains exceptionally indicated for men. In the case of breast cancer, PARP inhibitors are a promising new class of treatment for BRCA germline mutations. /AbstractText AbstractText Label CONCLUSION A discipline resolutely focused on understanding molecular mechanisms, screening and preventive medicine/surgery, oncology genetics is currently also involved in new medical/surgical approaches, the long-term benefits/risks of which will need to be monitored. /AbstractText
3
149-157
52
brca; breast canceroncog; enetics; predisposition; risk-reducing mastectomy
06
Mars
S2468-7189(24)00002-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
Femelle
humains
Mâle
sujet âgé
prédisposition génétique à une maladie
tumeurs du sein
tumeurs du sein
tumeurs du sein
gène BRCA2
facteurs de risque

---
Évaluation de la structure factorielle et des qualités psychométriques de l'Échelle de Fatigue Pandémique parmi la population adulte québécoise.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38193199
https://journals.sagepub.com/doi/10.1177/07067437231223331?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub 0pubmed
Marleau JD
Landaverde E
Généreux M
10.1177/07067437231223331
AbstractText Label OBJECTIVE The objective of the study is to evaluate the factorial structure and the psychometric qualities of the Pandemic Fatigue Scale among the Quebec adult population. /AbstractText AbstractText Label METHOD The data analyzed come from a web survey conducted in October 2021 among 10 368 adults residing in Quebec. The scale's factor structure and invariance by gender, age and language used to complete the questionnaire were tested using confirmatory factor analyses. Convergent and divergent validity were also assessed. Finally, the reliability of the scale was estimated from the alpha and omega coefficients. /AbstractText AbstractText Label RESULTS The analyzes suggest the presence of a bidimensional structure in the sample of Quebec adults with informational fatigue and behavioral fatigue. The invariance of the measure is noted for sex, for age subgroups and for the language used for the questionnaire. The results of convergent and divergent validity provide additional evidence for the validity of the scale. Finally, the reliability of the scale scores is excellent. /AbstractText AbstractText Label CONCLUSION The results support the presence of a bidimensional structure as in the initial work of Lilleholt et al. They also confirm that the scale has good psychometric qualities and that it can be used among the adult population of Quebec. /AbstractText AbstractText Label OBJECTIF L’objectif de l’étude est d’évaluer la structure factorielle et les qualités psychométriques de l’Échelle de Fatigue Pandémique parmi la population adulte québécoise. /AbstractText AbstractText Label MÉTHODE Les données analysées proviennent d’une enquête Web réalisée en octobre 2021 auprès de 10 368 adultes résidant au Québec. La structure factorielle de l’échelle et l’invariance selon le sexe, l’âge et la langue utilisée pour le questionnaire ont été testées à l’aide d’analyses factorielles confirmatoires. La validité convergente et divergente ont aussi été évaluées. Enfin, la fidélité de l’échelle a été estimée à partir des coefficients alpha et oméga total. /AbstractText AbstractText Label RÉSULTATS Les analyses suggèrent la présence d’une structure bidimensionnelle dans l’échantillon d’adultes québécois avec la fatigue informationnelle et la fatigue comportementale. L’invariance de la mesure est notée pour le sexe, pour les groupes d’âge et pour la langue utilisée pour la complétion du questionnaire. Les résultats de la validité convergente et divergente apportent des preuves supplémentaires à la validité de l’échelle. Enfin, la fidélité des scores de l’échelle est excellente. /AbstractText AbstractText Label CONCLUSION Les résultats appuient la présence d’une structure bidimensionnelle comme dans les travaux initiaux de Lilleholt et coll. Ils permettent également d’affirmer que l’échelle possède de bonnes qualités psychométriques et qu’elle peut être utilisée parmi la population adulte québécoise. /AbstractText
7067437231223331
quebec adults; adultes québécois; analyse factorielle exploratoire et confirmatoire.; behavioral fatigue; exploratory and confirmatory factor analysis; fatigue comportementale; fatigue informationnelle; fatigue pandémique; informational fatigue; pandemic fatigue; validity and reliability; validité et fidélité
09
Janvier
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Doit-on prendre en compte le stress informationnel de l’oncologue médical ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38199834
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00444-7
Penel N
Mailliez A
Pannier D
Ducrocq C
10.1016/j.bulcan.2023.11.008
Information overload, informational stress and its deleterious consequences constitute a subject of growing interest in the way of work. This is quite well documented among anesthesiologists. Studies have also been carried out on cancer patients or on the general public in terms of cancer prevention. After having defined the concepts and the consequences, we hypothesize the presence of informational stress among medical oncologists. We illustrate this hypothesis regarding adjuvant treatment of breast cancer. Specific studies (qualitative and quantitative ones) would be particularly interesting in oncology.
2
222-227
111
hyperconnexion; informational stress; medical decision-making; prise de décision médicale; stress informationnel
09
Février
S0007-4551(23)00444-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
Femelle
prise de décision
tumeurs du sein
oncologie médicale

---
Pronostic obstétrical et néonatal des patientes ayant un antécédent de mutilation génitale féminine.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38211770
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00006-0
Selides S
Nallet C
Vouga M
Mottet N
Ramanah R
10.1016/j.gofs.2024.01.002
AbstractText Label OBJECTIVE Female genital mutilation (FGM) covers all procedures involving partial or total removal of the external genitalia for non-therapeutic purposes. The period of pregnancy and childbirth is probably more at risk of complications for these women. The main aim of this study was to compare obstetrical, maternal and neonatal outcomes in patients with a history of female genital mutilation with patients without such a history. /AbstractText AbstractText Label METHODS All deliveries taking place between January 2005 and June 2022 at Besançon University Hospital in patients with a history of FGM were included. This group was compared with a randomly selected group of deliveries of patients with no history of FGM. A total of 87 deliveries with a history of FGM were included and compared with 696 deliveries with no history of FGM. /AbstractText AbstractText Label RESULTS There were significantly more instrumental deliveries (27.6% vs. 17.5%, p 0.01), more caesarean sections (23% vs. 14.1%, p 0.01), more episiotomies (9.2% vs. 0.7%, p 0.01), more first-degree perineal tears (30.8% vs. 20.8%, p 0.02), second-degree (13.9% vs. 5.3%, p 0, 01), third-degree (3.1% vs. 0.2%, p 0.02), more anterior perineal tears (23.1% vs. 2.5%, p 0.01), increased duration of pushing efforts (13 mins vs. 10 mins, p 0.05) and greater blood loss (297 cc vs. 165 cc, p 0.01) in the group with a history of FGM. There was no statistically significant difference in neonatal outcome. /AbstractText AbstractText Label CONCLUSION The obstetrical prognosis of patients with a history of FGM is significantly poorer. Neonatal prognosis remains unchanged. /AbstractText
excision; female genital mutilation; infibulation; prognosis
09
Janvier
S2468-7189(24)00006-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Une cause inhabituelle de masse palpébrale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38212205
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00570-3
Sarubbi C
Simonin M
Gauthier AS
Solecki L
10.1016/j.jfo.2023.104038
2
104038
47
10
Février
S0181-5512(23)00570-3
publication avant impression
Accès restreint
lettre
humains
tumeurs de la paupière
tumeurs de la paupière
paupières
blépharoptose

---
Caractéristiques et profils évolutifs des patients avec un diagnostic récent d’artérite à cellules géantes, étude NEWTON.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216390
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01322-X
Goncalves L
Tran VT
Chauffier J
Bourdin V
Nassarmadji K
Vanjak A
Bigot W
Burlacu R
Champion K
Lopes A
Depont A
Borrero BA
Mangin O
Adle-Biassette H
Bonnin P
Boutigny A
Bonnin S
Neumann L
Mouly S
Sène D
Comarmond C
10.1016/j.revmed.2023.12.005
AbstractText Label INTRODUCTION The management of giant cell arteritis (GCA) has evolved with the arrival of tocilizumab (TCZ) and the use of PET/CT. Our objective is to describe the characteristics and followup of patients with recent diagnosis of GCA in current care. /AbstractText AbstractText Label PATIENTS AND METHODS The NEWTON cohort is a monocentric retrospective cohort based on data collected from 60 GCA patients diagnosed between 2017 and 2022 according to the ACR/EULAR 2022 criteria. /AbstractText AbstractText Label RESULTS The median age at diagnosis was 73 [68.75; 81] years old. At diagnosis, the main manifestations were unusual temporal headaches in 48 (80 %) and an inflammatory syndrome in 50 (83 %) patients. Temporal artery biopsy confirmed the diagnosis in 49/58 (84 %) patients. Doppler of the temporal arteries found a halo in 12/23 (52 %) patients. The PET/CT found hypermetabolism in 19/43 (44 %) patients. Prednisone was stopped in 17.5 [12.75; 24.25] months. During follow-up, 22 (37 %) patients received TCZ. At least one complication of corticosteroid therapy was observed in 22 (37 %) patients. After a median follow-up of 24 [12; 42] months, 25 (42 %) patients relapsed. At the end of the follow-up, 29 (48.3 %) patients were weaned from corticosteroid therapy and 15 (25 %) were on TCZ. /AbstractText AbstractText Label CONCLUSION Despite the increasing use of TCZ in the therapeutic arsenal and of the PET/CT in the imaging tools of GCA patients, relapses and complications of corticosteroid therapy remain frequent, observed in more than a third of patients. /AbstractText
artérite à cellules géantes; giant cell arteritis; large vessel; pet scanner; positron emisson tomography; rechute; relapse; tocilizumab; vascularite des gros vaisseaux
11
Janvier
S0248-8663(23)01322-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Une rétinopathie peut en cacher une autre.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216406
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00578-8
Timoumi R
Giocanti-Aurégan A
Fajnkuchen F
Torres-Villaros H
10.1016/j.jfo.2023.104046
3
104046
47
11
Mars
S0181-5512(23)00578-8
publication avant impression
Accès restreint
lettre
humains
nouveau-né
rétinopathie du prématuré

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1. Adénome vésiculaire d’architecture papillaire.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216435
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00235-3
Guyétant S
10.1016/j.annpat.2023.12.007
2
96-100
44
11
Mars
S0242-6498(23)00235-3
publication avant impression
Accès restreint
article de périodique
humains
tumeurs de la thyroïde
adénocarcinome folliculaire

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Localisation hépatique isolée d’une histiocytose langerhansienne : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216436
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00229-8
Allaume P
Meneyrol E
Bernard G
Houssel-Debry P
Emile JF
Turlin B
10.1016/j.annpat.2023.12.001
Langerhans cell histiocytosis (LCH) is a disease whose physiopathology remains unclear, involving both inflammatory processes and clonal proliferation. It is observable at any given age, although about ten times more frequent in children than adults. Hepatic involvement is not rare, mostly part of a systemic disease, and linked to a poor prognosis. We report here a case of LCH with solitary hepatic involvement in a 74 year-old patient. This case demonstrated molecular anomaly of the MAPK pathway, BRAF N486_P490del. Through this observation, we precise the epidemiological and histological aspects and diagnostic criteria of this rare disease.
1
69-74
44
cholangite; cholangitis; foie; histiocytose; histiocytosis; langerhans; liver; mapk
11
Février
S0242-6498(23)00229-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
adulte
enfant
humains
sujet âgé
histiocytose à cellules de langerhans
maladies rares
foie

---
trimestre de la grossesse en population à bas risque?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218336
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00005-9
Quarello E
10.1016/j.gofs.2024.01.001
11
Janvier
S2468-7189(24)00005-9
publication avant impression
Accès restreint
éditorial

---
Agents antibactériens et lutte contre la résistance aux antibiotiques: analyse de la consommation et des dépenses d'une entreprise italienne de soins de santé dans le monde réel.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218426
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00001-4
Ferrara F
Capuozzo M
Pasquinucci R
Langella R
Trama U
Nava E
Zovi A
10.1016/j.pharma.2024.01.001
antibiotic resistance; antibiotics; appropriateness; assessment; consumption; defined daily dose
11
Janvier
S0003-4509(24)00001-4
publication avant impression
Accès restreint
article de périodique

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Atteinte sévère de l’intestin grêle et pseudo-obstruction intestinale chronique au cours de la sclérodermie systémique : bases physiopathologiques, diagnostiques et thérapeutiques, dont la nutrition parentérale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38388303
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00055-9
Suzon B
Louis-Sidney F
Abel A
Moinet F
Bagoée C
Henry K
Coco-Viloin I
Cougnaud R
Wolff S
Guilpain P
Rivière S
Flori N
Deligny C
Maria A
10.1016/j.revmed.2024.02.001
Gastrointestinal involvement in systemic sclerosis can be severe, reaching the critical point of chronic intestinal pseudo-obstruction, secondary to major disorders of small bowel motility. It is associated with some clinical and biological characteristics, in particular the positivity of anti-fibrillarin/U3RNP antibodies. Chronic intestinal pseudo-obstruction (CIPO) is complicated by a small intestinal bacterial overgrowth that requires cyclic antibiotic therapy. CIPO leads to a reduction of the food intake, due to painful symptoms, nausea and vomiting caused by meals, and ultimately to severe malnutrition. Meal splitting is often transiently effective and patients require exogenous nutritional support, mostly parenteral. Systemic sclerosis is not an obstacle to initiation and long-term continuation of parenteral nutrition and central venous catheter implantation is not associated with an increased risk of cutaneous or infectious complications. However, continuation of long-term parenteral nutrition requires monitoring in an expert nutrition center in order to adapt nutritional volumes and intakes and to limit potentially fatal cardiac and hepatobiliary complications. In addition to nutrition, prokinetic treatments, whose side effects must be known, can be associated. Invasive procedures, whose risk-benefit ratio must be carefully assessed, can also be used to treat symptoms exclusively.
3
147-155
45
chronic intestinal pseudo-obstruction; nutrition parentérale; parenteral nutrition; prokinetics; prokinétiques; pseudo-obstruction intestinale chronique; sclérodermie systémique; systemic sclerosis
21
Mars
S0248-8663(24)00055-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
pseudo-obstruction intestinale
pseudo-obstruction intestinale
pseudo-obstruction intestinale
nutrition parentérale
intestin grêle
sclérodermie systémique
sclérodermie systémique
sclérodermie systémique
Appréciation des risques
maladie chronique

---
Chez les sujets ayant eu un accident vasculaire cérébral ischémique mineur ou un accident ischémique transitoire à haut risque dans les 72heures, est-ce que la combinaison aspirine et clopidogrel donnée pour 21jours diminue la récidive d’AVC à 90jours comparativement à l’aspirine seule, tout en étant sécuritaire ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38388304
Lanthier L
Plourde MÉ
Cauchon M
10.1016/j.revmed.2024.02.002
accident vasculaire cérébral; antiplatelet therapy; aspirin; aspirine; clopidogrel; stroke; thérapie antiplaquettaire
21
Février
S0248-8663(24)00056-0
publication avant impression
Accès restreint
lettre

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5. High-grade Tall cell papillary carcinoma.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38388328
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00043-9
Decaussin-Petrucci M
10.1016/j.annpat.2024.02.002
2
114-119
44
21
Mars
S0242-6498(24)00043-9
publication avant impression
Accès restreint
article de périodique
humains
carcinome papillaire

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4. Carcinome vésiculaire encapsulé.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38388329
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00041-5
Belleannée G
10.1016/j.annpat.2024.01.016
2
108-113
44
21
Mars
S0242-6498(24)00041-5
publication avant impression
Accès restreint
article de périodique
humains
tumeurs de la thyroïde
carcinome papillaire folliculaire
tumeurs épithéliales épidermoïdes et glandulaires
adénocarcinome folliculaire

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Le myofibroblastome palissadique intraganglionnaire : une cause rare d’adénopathie inguinale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38395714
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)00881-0
Gomes de Pinho Q
Dales JP
Macagno N
Houser F
Delayre T
Imbert-Joscht I
Rossi P
Benyamine A
Granel B
10.1016/j.revmed.2023.10.439
AbstractText Label INTRODUCTION Lymphadenopathies are a major cause of consultation in internal medicine, with various causes of diagnosis. Unexplained persistent lymphadenopathy must be biopsied to rule out malignant tumor. /AbstractText AbstractText Label CASE REPORT We report the case of a 53-year-old man, with inguinal lymphadenopathy evolving for more than one year. The patient had no associated symptoms and his blood tests were unremarkable. Due to the progression of the adenopathy and its hypermetabolism on PET-CT, an excisional biopsy was performed. Histological analysis revealed an intranodal proliferation of spindle cells with a palisading pattern. β-catenine and smooth muscle actin labelling were positive, leading to the diagnosis of intranodal palisaded myofibroblastoma, a benign tumour. /AbstractText AbstractText Label CONCLUSION Intranodal palisaded myofibroblastoma is a rare benign cause of adenopathy, with often inguinal lymph node localization and slow growth and without risk of recurrence after surgical removal. /AbstractText
3
138-141
45
adénopathie; ctnnb1 catenin beta 1 gene; gène de la bêtacaténine ctnnb1; inguinal tumor; intranodal palisaded myofibroblastoma; lymphadenopathy; myofibroblastome palissadique ganglionnaire; tumeur inguinale
22
Mars
S0248-8663(23)00881-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
Mâle
humains
adulte d'âge moyen
noeuds lymphatiques
tumeurs du tissu musculaire
tumeurs du tissu musculaire
tumeurs du tissu musculaire
biopsie

---
Réponse de Sentilhes L., Sénat M.V., Bouchghoul H., Delorme P., Gallot D., Garabedian C., Madar H., Sananès L., Perrotin F., Schmitz T., à l’article de Boujenah J. intitulé « La cholestase gravidique : pour une vision holistique de la femme. À propos des examens complémentaires lors du diagnostic ». Gynecol Obstet Fertil 2024 ; 52(6). 10.1016/j.gofs.2024.02.023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38408606
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00079-5
Sentilhes L
Sénat MV
Bouchghoul H
Delorme P
Gallot D
Garabedian C
Madar H
Sananès N
Perrotin F
Schmitz T
10.1016/j.gofs.2024.02.024
pitches trial; intrahepatic cholestasis of pregnancy; long term outcome; maternal morbidity; screening
24
Février
S2468-7189(24)00079-5
publication avant impression
Accès restreint
lettre

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La cholestase gravidique: pour une vision holistique de la femme. À propos des examens complémentaires lors du diagnostic.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38408607
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00078-3
Boujenah J
10.1016/j.gofs.2024.02.023
24
Février
S2468-7189(24)00078-3
publication avant impression
Accès restreint
lettre

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Réforme de l’Accès dérogatoire: impact sur la gestion dans une PUI et identification des risques.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38408723
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00032-4
Jouhet O
Demir J
Sitbon M
Bildan MA
Bros A
Kim E
Godron N
Madelaine I
Deville L
10.1016/j.pharma.2024.02.012
The reform of derogatory access authorisations (DAs) on 1st July 2021 has distorted the routine of the hospital pharmacists dealing with innovative medicines that are waiting for marketing authorization or approval. There are two distinct categories of DAs: Compassionate Access Authorisations (CAAs) are granted by the French National Agency for the Safety of Medicines (ANSM) while Early Access Authorisations (EAPs) are granted at the request of pharmaceutical companies by the French National Authority for Health (HAS). All AAPs and a majority of the AACs are supported by a Protocol for Therapeutic Use and Data Collection (PTU-DC). The aim of this study is to assess the impact of the reform on pharmacy process one year following its implementation, and to identify the risks related to the new circuits. The working group, composed of three pharmacists carried out an initial assessment of the effects first measured the impact of the reform on medicine processes in DAs. They performed a comparison of the changes in their management methods: 3 months prior to the reform (M0), and 3 months (M3) and 12 months (M12) post-reform. Risks analysis was conducted using the FMEA (Failure Modes, Effects and Criticality Analysis) method. The analysis was limited to the process steps specific related to DAs drugs were analyzed. The critical severity of the risk situations identified was rated. A critical hierarchy matrix was used to establish priority actions. The priority actions to be taken were determined using the critical hierarchy matrix. Over the span of one year, the number of DAs in our establishment showed a 31.7% increase, from 41 at M0 to 54 at M12. At M0, the proportion of drugs needed inclusion via a drug- specific digital platform, specific to each drug, stood at 27% (11/41) of drugs at M0 while at M12, it rose to 52% (28/54). The percentage of PTU-DCs therefore increased by a factor of 1.7, rising from 29% (12/41) at M0 to 47% (21/45) at M3 and 60% (32/54) at M12. For orders, which are always nominative, approval depends on both the presence of the PTU-DC tracking sheet being present in 12% of PAAs, and the inclusion number in 26% of PAAs. The risk analysis shows 44 failure modes and 28 risk situations. Among the failure modes, 33 have a consequence of acceptable or tolerable criticality under control, whilst 11 are deemed of unacceptable criticality. A suitable control method exists has been identifies for 3 of them. Finally, the ranking evaluation of criticalities has highlighted 4 situations which require immediate action as a priority: delivery times, obtaining completed tracking sheets and ordering procedures. The aim of the DAs reform is to simplify access to innovative medicines. However, the reform has significant and damaging repercussions on pharmaceutical activities. Corrective measures need to be taken in conjunction with all parties involved in the circuits including laboratories and service providers (CROs), authorities and healthcare professionals.
accès dérogatoires; early access program; analyse de risques; risk analysis
24
Février
S0003-4509(24)00032-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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you leave a hole.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38409647
https://doi.org/10.1002/pbc.30917
Kaye EC
10.1002/pbc.30917
5
e30917
71
26
Mai
publication avant impression
Accès restreint
article de périodique
humains
emploi

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État des lieux des connaissances des internes et chefs de clinique d’urologie sur la prise en charge neuro-urologique des patients spina bifida en France.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38417189
https://linkinghub.elsevier.com/retrieve/pii/S2950-3930(24)00035-4
Levy S
Dequirez PL
Mercier J
Taha F
Goujon A
Seguier D
Mesnard B
Seizilles de Mazancourt E
Joussen G
Margue G
Berchiche W
Anastay V
Deleuze C
Kaulanjan K
Cotte J
Peyrottes A
Gamé X
Peyronnet B
10.1016/j.fjurol.2024.102580
AbstractText Label OBJECTIVE To assess the current knowledge of French urology residents and fellows about neurogenic lower urinary tract dysfunction and their management in patients with spina bifida. /AbstractText AbstractText Label MATERIAL AND METHOD A 7-question questionnaire, covering the responder's experience and the various stages in the neuro-urological management of spina bifida, was drafted by an expert urologist. Responses were collected within 5days of being e-mailed to members of the Association française des urologues en formation (AFUF), and a descriptive analysis was carried out. /AbstractText AbstractText Label RESULTS Of the 448 members, 155 completed the questionnaire. Of the participants, 83.8% said they knew the definition of spina bifida, and 76.8% had already had to care for a spina bifida patient. Of the participants, 48.4% correctly estimated the number of spina bifida patients in France. Neurogenic lower urinary tract dysfunction to look for and the specificities of management seemed to have been acquired by a majority of respondents (correct response rates of 70.7% and 75.4%, respectively), unlike the extra-urological aspects (53.9%), and the choice of examinations useful for the initial work-up and follow-up (55.8%). /AbstractText AbstractText Label CONCLUSION While the expected neurogenic lower urinary tract dysfunction and the specificities of therapeutic management of spina bifida patients appear to be well known to urologists in training, knowledge of extra-urological symptoms and the choice of examinations could be improved. These results could be used to adjust the teaching given to French urologists in training on the urological management of spina bifida patients. /AbstractText AbstractText Label LEVEL OF EVIDENCE Grade 4. /AbstractText
3
102580
34
education; formation; internes; neuro-urologie; neuro-urology; pédagogie; residents; spina bifida; training
27
Février
S2950-3930(24)00035-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Endocardite infectieuse : facteurs prédictifs de mortalité intrahospitalière.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38417204
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(24)00019-2
Safia O
Asma J
Hana H
Sarra J
Aymen Z
Mouna J
Amal M
Rym BK
10.1016/j.ancard.2024.101740
AbstractText Label INTRODUCTION Infective endocarditis (IE) remains a serious disease with significant morbidity and mortality despite therapeutic advancements. The aim of our study was to determine the predictive factors of in-hospital mortality. /AbstractText AbstractText Label PATIENTS AND METHODS A prospective comparative study over a period of 54 months was conducted, including all patients admitted for definite infective endocarditis, diagnosed according to the modified Duke criteria published in 2015 by the European Society of Cardiology. /AbstractText AbstractText Label RESULTS Thirty-four patients were included. Drug addiction was the main risk factor for infective endocarditis (56%). Tricuspid valve involvement was predominant (50%). Staphylococcus aureus was the most commonly isolated pathogen (65%). In-hospital mortality rate was 47%. In multivariate analysis, predictive factors for mortality were acute heart failure (OR 7.4; p 0.026; 95% CI [1.2-44]) and cerebral embolic localization (OR 11.1; p 0.024; 95% CI [13-90]). /AbstractText AbstractText Label CONCLUSIONS Cardiac and cerebral complications influence the prognosis of IE. Thus, close collaboration among multidisciplinary teams is necessary for improved diagnostic and therapeutic management. /AbstractText
2
101740
73
diagnosis; diagnostic; emergency; endocardite; endocarditis; epidemiology; prognosis; pronostic; urgence; épidémiologie
27
Avril
S0003-3928(24)00019-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
études prospectives
mortalité hospitalière
études rétrospectives
endocardite bactérienne
endocardite
facteurs de risque

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Prévention de l’allo-immunisation anti-RH1 au premier trimestre de la grossesse: recommandations pour la pratique clinique du Collège National des Gynécologues-Obstétriciens Français.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38417789
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00081-3
Vigoureux S
Maurice P
Sibiude J
Garabedian C
Sananès N
10.1016/j.gofs.2024.02.026
AbstractText Label OBJECTIVE To provide recommendations for the prevention of Rh D alloimmunization in the first trimester of pregnancy. /AbstractText AbstractText Label MATERIALS AND METHODS The quality of evidence of the literature was assessed following the GRADE methodology with questions formulated in the PICO format (Patients, Intervention, Comparison, Outcome) and outcomes defined a priori and classified according to their importance. An extensive bibliographic search was performed on Pubmed, Cochrane, EMBASE, and Google Scholar databases. The quality of evidence was assessed (high, moderate, low, very low) and a recommendation was formulated: (i) strong, (ii) weak, or (iii) no recommendation. The recommendations were reviewed in two rounds with reviewers from the scientific board of the French College of the OB/GYN (Delphi survey) to select the consensus recommendations. /AbstractText AbstractText Label RESULTS The three recommendations from PICO questions reached agreement using the Delphi method. It is recommended not to administer Rh D immunoglobulin before 12 weeks of gestation to reduce the risk of alloimmunization in case of abortion or miscarriage, in RhD negative patients when the genitor is RhD positive or unknown (Weak recommendation. Very low-quality evidence). It is recommended not to administer Rh D immunoglobulin before 12 weeks of gestation to reduce the risk of alloimmunization in cases of bleeding in an ongoing intrauterine pregnancy (Weak recommendation. Very low-quality evidence). The literature data are insufficient in quality and quantity to determine if the injection of Rh D immunoglobulin reduces the risk of alloimmunization in the case of an ectopic pregnancy (No recommendation. Very low-quality evidence). /AbstractText AbstractText Label CONCLUSION Even though the quality of evidence from the studies is very low, it is recommended not to administer Rh D immunoglobulin in case of abortion, miscarriage or bleeding before 12 weeks of amenorrhea. The quality of evidence was too low to issue a recommendation regarding ectopic pregnancy. /AbstractText
rhesus d; abortion; alloimmunization; bleeding; ectopic pregnancy; first trimester; miscarriage; prevention
26
Février
S2468-7189(24)00081-3
publication avant impression
Accès restreint
résumé en anglais
guide de bonnes pratiques

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6. Anaplastic thyroid carcinoma, epidermoid subtype.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38418289
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00042-7
Decaussin-Petrucci M
10.1016/j.annpat.2024.02.001
2
120-124
44
27
Mars
S0242-6498(24)00042-7
publication avant impression
Accès restreint
article de périodique
humains
Carcinome anaplasique de la thyroïde
tumeurs de la thyroïde

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Histoséminaire biopsies du péritoine - Introduction.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38418290
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00035-X
Benzerdjeb N
Dartigues P
Illac C
Valmary-Degano S
10.1016/j.annpat.2024.01.010
27
Février
S0242-6498(24)00035-X
publication avant impression
Accès restreint
article de périodique

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Référentiel national de traitement des carcinomes épidermoïdes des voies aérodigestives supérieures – Principes généraux de traitement.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38418334
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00024-9
Barry B
Dolivet G
Clatot F
Huguet F
Abdeddaim C
Baujat B
Blanchard N
Calais G
Carrat X
Chatellier A
Coste F
Cupissol D
Cuvelier P
De Mones Del Pujol E
Deneuve S
Duffas O
Dupret-Bories A
Even C
Evrard C
Evrard D
Faivre S
Fakhry N
Garrel R
Gorphe P
Houliat T
Kaminsky MC
Krebs L
Lapeyre M
Lindas P
Malard O
Mirghani H
Mondina M
Moriniere S
Mouawad F
Pestre-Munier J
Pham Dang N
Picard A
Ramin L
Renard S
Salvan D
Schernberg A
Sire C
Thariat J
Vanbockstael J
Vo Tan D
Wojcik T
Klein I
Block V
Baumann-Bouscaud L
De Raucourt D
10.1016/j.bulcan.2023.12.007
AbstractText Label OBJECTIVES The management of upper aerodigestive tract cancers is a complex specialty. It is essential to provide an update to establish optimal care. At the initiative of the INCa and under the auspices of the SFORL, the scientific committee, led by Professor Béatrix Barry, Dr. Gilles Dolivet, and Dr. Dominique De Raucourt, decided to develop a reference framework aimed at defining, in a scientific and consensus-based manner, the general principles of treatment for upper aerodigestive tract cancers applicable to all sub-locations. /AbstractText AbstractText Label METHODOLOGY To develop this framework, a multidisciplinary team of practitioners was formed. A systematic analysis of the literature was conducted to produce recommendations classified by grades, in accordance with the standards of the French National Authority for Health (HAS). /AbstractText AbstractText Label RESULTS The grading of recommendations according to HAS standards has allowed the establishment of a reference for patient care based on several criteria. In this framework, patients benefit from differentiated care based on prognostic factors they present (age, comorbidities, TNM status, HPV status, etc.), conditions of implementation, and quality criteria for indicated surgery (operability, resectability, margin quality, mutilation, salvage surgery), as well as quality criteria for radiotherapy (target volume, implementation time, etc.). The role of medical and postoperative treatments was also evaluated based on specific criteria. Finally, supportive care must be organized from the beginning and throughout the patients' care journey. /AbstractText AbstractText Label CONCLUSION All collected data have led to the development of a comprehensive framework aimed at harmonizing practices nationally, facilitating decision-making in multidisciplinary consultation meetings, promoting equality in practices, and providing a state-of-the-art and reference practices for assessing the quality of care. This new framework is intended to be updated every 5 years to best reflect the latest advances in the field. /AbstractText
4
393-415
111
carcinomes épidermoïdes des voies aérodigestives supérieures; chirurgie; facteurs pronostics; literature review; medical treatments; prognostic factors; radiotherapy; radiothérapie; recommandations; recommendations; revue de la littérature; soins de support; squamous cell carcinomas of the upper aerodigestive tract; supportive care; surgery; traitements; traitements médicaux; treatments
27
Avril
S0007-4551(24)00024-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
carcinome épidermoïde
tube digestif

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Ischémie du segment antérieur de l’œil secondaire à une cryoglobulinémie de type 1 : à propos d’un cas et revue de la littérature.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38418361
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00060-2
Wyttynck A
Raby M
Le Gall F
Dupuy A
Soethoudt M
Fouchard M
10.1016/j.revmed.2024.02.006
AbstractText Label INTRODUCTION Type 1 cryoglobulinemia is characterized by a large number of clinical signs. The lack of specificity of these signs can make diagnosis difficult. Ocular manifestations are rarely described across medical literature. Only 15 cases of ophthalmological involvement secondary to cryoglobulinaemia have been reported. /AbstractText AbstractText Label COMMENT We report the case of a 69-year-old patient with cutaneous type 1 cryoglobulinaemia. He presented with bilateral anterior segment ischemia without retinal involvement with unilateral neovascularisation. Treatment of the B lymphocyte clone with rituximab and bendamustine and plasma exchange were initiated with successfully. Two similar cases describing ischaemic damage to the iris during type 1 cryoglobulinemia have been reported in the literature. /AbstractText AbstractText Label CONCLUSION Irial ischaemia should be considered as a potential in type 1 cryoglobulinaemia. /AbstractText
anterior segment ischemia; atteinte oculaire; cryoglobulinemia; cryoglobulinémie; glaucome néovasculaire; ischémie segment antérieur; neovascular glaucoma; ocular involvement
27
Février
S0248-8663(24)00060-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Les enjeux éthiques de la réhabilitation psychosociale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38423859
https://linkinghub.elsevier.com/retrieve/pii/S0013-7006(23)00200-2
Richa S
Choueifati D
Chemali N
Amado I
10.1016/j.encep.2023.09.003
Psychosocial rehabilitation (PSR) is a therapeutic approach which aims to improve the overall functioning of people with severe mental disorders. We detail the principles of bioethics applied to care and seek to demonstrate how PSR meets the requirements of a humanistic psychiatry. The four fundamental principles of the ethics of care - autonomy, beneficence, non-maleficence and justice - are found in the practice of PSR. The practice and implementation of PSR is strongly encouraged in universal codes of ethics.
autonomie; autonomy; cognitive remediation; ethics; psychosocial; psychosociale; rehabilitation; remédiation cognitive; réhabilitation; éthique
28
Février
S0013-7006(23)00200-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Analyse d’une cohorte française d’encéphalopathies néonatales anoxo-ischémiques à l’ère de l’hypothermie thérapeutique: questions-réponses.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38428637
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00080-1
Debillon T
Beck J
Guellec I
Vilotitch A
Pierrat V
Baud O
Sentilhes L
Kayem G
Ego A
10.1016/j.gofs.2024.02.025
AbstractText Label OBJECTIVE to improve knowledge of Neonatal Hypoxic-Ischemic Encephalopathy, a prospective, nationwide, population-based cohort of affected children is being set up between September 2015 and March 2017. /AbstractText AbstractText Label METHODS during this period, 794 cases are collected, with information on pregnancy, delivery, neonatal stay and outcome at the end of hospitalization. Clinical and parental questionnaire follow-up is planned until the child is 4 years old. /AbstractText AbstractText Label RESULTS this article presents the clinical presentation of the newborns included, the analysis of factors associated with short-term outcome at hospital discharge and the organizational factors associated with treatment with Therapeutic Hypothermia. /AbstractText AbstractText Label CONCLUSION these data illustrate the value of a prospective cohort to analyze the management of EAI in France. /AbstractText
neonatal encephalopathy; optimal care; risk factors; short term outcome; therapeutic hypothermia
28
Février
S2468-7189(24)00080-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Milan 2.0 – 2023 : apports et nouveautés de la seconde édition du système de Milan pour rapporter la cytopathologie des glandes salivaires.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38429132
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00037-3
Bigorgne C
10.1016/j.annpat.2024.01.012
actualisation; cytopathologie; glandes salivaires; seconde édition; système de milan pour rapporter la cytopathologie des glandes salivaires; terminologie
29
Février
S0242-6498(24)00037-3
publication avant impression
Accès restreint
article de périodique

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Gestion périopératoire des cigarettes conventionnelles et électroniques. Actualisation 2023. Une revue narrative de la littérature.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38429192
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00115-3
Mestdag M
Degey S
Deflandre E
10.1016/j.rmr.2024.02.001
AbstractText Label INTRODUCTION Tobacco addiction is the leading cause of preventable death. During the perioperative period, patients who smoke are at increased risk of systemic as well as surgical site complications. /AbstractText AbstractText Label STATE OF THE ART Surgery is an ideal time for change of lifestyle habits. It is vital to seize this opportunity to improve the patient's health in the long- as well as the short-term. Smoking cessation should be encouraged in all surgical patients. Initiating smoking cessation combines pharmacological treatment and a behavioral approach. In this field, significant advances have been recorded over the last decade. This review proposes a practical approach that every practitioner will be able to apply. /AbstractText AbstractText Label PERSPECTIVES In this review, we will also examine ongoing research, particularly as regards vaccination and the place of biomarkers. /AbstractText AbstractText Label CONCLUSIONS Smoking represents a major source of health-related complications. Smoking cessation must therefore remain a priority in the management of medical and surgical patients. /AbstractText
3
237-247
41
complications postopératoires; médecine personnalisée; perioperative complication; personalized medicine; sevrage tabagique; smoking; smoking cessation; tabagisme
29
Mars
S0761-8425(24)00115-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
Arrêter de fumer
Dispositifs électroniques d'administration de nicotine
Fumer
Fumer
Fumer

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Ablation endoscopique par micro-onde : une nouvelle alternative pour le traitement loco-régional des tumeurs pulmonaires malignes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38429193
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00134-7
Bondue B
Leduc D
10.1016/j.rmr.2024.02.004
3
175-179
41
bronchoscopie; bronchoscopy; cancer du poumon; electromagnetic navigation bronchoscopy; lung cancer; micro-wave ablation; navigation électro-magnétique; radiothérapie stéréotaxique; stereotaxic radiotherapy; thermo-ablation par micro-onde
29
Mars
S0761-8425(24)00134-7
publication avant impression
Accès restreint
éditorial
humains
bronchoscopie
tumeurs du poumon
tumeurs du poumon
nodule pulmonaire solitaire
phénomènes électromagnétiques

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Profil épidémiologique et évolutif de l’asthme professionnel des travailleurs tunisiens.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38429194
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00116-5
Gaddour A
Chatti S
Chouchene A
Kacem I
Bouhoula M
Aloui A
Marnaoui M
Maoua M
Brahem A
Kalboussi H
El Maalel O
Mrizek N
10.1016/j.rmr.2024.02.002
AbstractText Label INTRODUCTION This study aims to identify the epidemiological and occupational characteristics of patients with occupational asthma (OA) and to assess their clinical evolution and occupational outcomes. /AbstractText AbstractText Label METHODS We carried out a descriptive epidemiological study over a period of five years (from 2012 to 2016) about the OA cases in the private sector reported in the Tunisian region of Zaghouan. /AbstractText AbstractText Label RESULTS All in all, 165 OA cases were reported during the study period, representing an annual incidence of 733.3 cases per 1,000,000 workers in the private sector. Our study population was composed predominantly (85.5%) of women, whose mean age was 41.5 6.8years. More than three quarters of the affected persons were working in the automobile industry, and most illnesses (77%) were attributable to isocyanates. The mean time to onset of the respiratory symptoms was longer for low molecular weight agents (13.6 3.1years) compared to high molecular weight agents (12.0 3.9years) (P 0.0006). The majority of OA cases (66.7%) lost their jobs. Job loss was significantly more frequent among asthmatic women and workers with OA due to isocyanates. Among the 62 cases of OA for whom risk factors were eliminated, 45 nonetheless remained symptomatic. /AbstractText AbstractText Label CONCLUSION Effective prevention strategies involving the various actors need to be implemented in work environments so as to reduce the frequency and the medico-legal repercussions of a disabling condition. /AbstractText
3
227-236
41
asthma; asthme; devenir professionnel; déclaration; epidemiology; occupational; occupational outcomes; professionnel; report; épidémiologie
29
Mars
S0761-8425(24)00116-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
isocyanates
humains
Femelle
adulte
adulte d'âge moyen
asthme professionnel
asthme professionnel
asthme professionnel
professions
incidence
facteurs de risque
maladies professionnelles
maladies professionnelles
exposition professionnelle

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Glaucome pigmentaire unilatéral dans le cadre d’un syndrome de Claude Bernard-Horner : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38429204
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00057-3
Tatry M
Brasnu E
Labbé A
Baudouin C
10.1016/j.jfo.2024.104112
4
104112
47
29
Avril
S0181-5512(24)00057-3
publication avant impression
Accès restreint
lettre
présentations de cas
humains
syndrome de Claude Bernard-Horner
syndrome de Claude Bernard-Horner
blépharoptose
glaucome à angle ouvert
glaucome à angle ouvert

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Oxygénothérapie hyperbare et maladies oculaires : une revue de la littérature.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38430627
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00052-4
Bastelica P
Florentin G
Baudouin C
Labbé A
10.1016/j.jfo.2024.104107
Hyperbaric oxygen therapy consists of breathing 100% oxygen continuously or intermittently in a chamber at a pressure equal to or greater than 1.4 absolute atmospheres. Indicated for the emergency treatment of carbon monoxide poisoning and other medical-surgical pathologies such as gas embolism or necrotizing soft-tissue infections, various studies have shown a beneficial effect of hyperbaric oxygen therapy in certain ocular pathologies, notably of microcirculatory origin, such as central retinal artery occlusion or macular edema linked to retinal vein occlusions. In addition, hyperbaric oxygen might represent an alternative treatment for ocular quinine toxicity and might also be useful as an adjuvant to surgery and antibiotics in cases of periorbital necrotizing fasciitis. On the other hand, oxygen in high concentrations has toxic ocular effects due to the production of reactive oxygen derivatives.
4
104107
47
cataract; cataracte; central retinal artery occlusion; hyperbaric oxygen therapy; occlusion de l’artère centrale de la rétine; oxygénothérapie hyperbare
01
Avril
S0181-5512(24)00052-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
oxygène
humains
oxygénation hyperbare
microcirculation
maladies de l'oeil
fasciite nécrosante

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Apport du scanner cardiaque dans la prise en charge des cardiopathies congénitales : expérience de l'institut de cardiologie d'Abidjan à propos de 27 cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38430813
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(24)00018-0
Avoh AEM
N'goran YNK
N'cho-Mottoh MP
Traore DF
Tano-Akoto M
Doh CZ
Vy L
Anzouan KJ
Kramoh KE
10.1016/j.ancard.2024.101739
AbstractText Label INTRODUCTION AND OBJECTIVES In contrast to developed countries, cardiac CT is not widely used in West Africa for the assessment of congenital heart disease, and has only recently been introduced in Côte d'Ivoire. The lack of data prompted this study, the aim of which was to describe our experience of the contribution of CT to the management of congenital heart disease in the Ivorian cardiology setting. /AbstractText AbstractText Label PATIENTS AND METHOD This was a prospective study which took place in the pediatric cardiology department over a period of 9 months (September 2022 to June 2023) which included all patients with congenital heart disease explored by echocardiography and cardiac scan. /AbstractText AbstractText Label RESULTS The average age was 5.7 4.7 years with extremes of 5 months and 16 years. We noted a female predominance with a sex ratio of 0.52. The main heart diseases were: tetralogy of Fallot (37.1%), followed by pulmonary atresia with open septum (18.52%). The assessment of the anatomy of the pulmonary arteries (81.48%), the search for aortopulmonary collaterals (59.63%) and finally the assessment of the anatomy of the aorta (18.52%) were the main indications. The practice of cardiac CT scanning has enabled better accuracy in the diagnosis and management of congenital heart disease in several cases: an interruption of the aortic arch was found in 1 case initially suspected of hypoplasia of the aortic arch, three cases of partial abnormal pulmonary venous return and one case of total abnormal pulmonary venous return. Also, agenesis of the left pulmonary artery with birth anomaly of the right coronary artery in the assessment of tetralogy of Fallot was found in 1 case. The CT scan made it possible to specify the exact topography of the aortopulmonary collaterals in four cases of pulmonary atresia with an open septum. /AbstractText AbstractText Label CONCLUSION CT has enabled better visualization of the arterial and venous pulmonary tree, identification and exact localization of aorto-pulmonary collaterals, precise description of the three-dimensional anatomy of the coronary arteries, and better precision of congenital anomalies of the aorta. /AbstractText
3
101739
73
cardiac scan; cardiopathies congénitales; congenital heart disease; extracardiac structure; scanner cardiaque; structure extracardiaque
01
Mars
S0003-3928(24)00018-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Le concept de pneumopathie interstitielle diffuse avec manifestations auto-immunes (IPAF).
2024
http://www.ncbi.nlm.nih.gov/pubmed/38433068
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00059-6
Bermudez J
Habert P
Coiffard B
10.1016/j.revmed.2024.02.005
Interstitial lung diseases (ILD) are a heterogeneous group of respiratory diseases often related to connective tissue diseases. Some patients will develop an ILD with autoimmune features without reaching the recommended criteria for autoimmune diseases. Their management is difficult because they have both features for idiopathic and connective tissue disease. To better identify these patients, the concept of interstitial pneumonia with autoimmune features (IPAF) has been created. The diagnosis relies on ILD without identified cause and the presence of at least one defined criterion among 2 of the 3 following domains: clinic, serologic, and morphologic. The mean age at diagnosis is 60, a sex ratio of 1/1, and depending on the authors close to 20% of patients with IPAF will develop a connective tissue disease according to the international criterion. Their prognosis is better than for patients with idiopathic ILD and with an average 5-year survival of 70%. Older age at diagnosis, a pattern of usual interstitial pneumonia, and an impaired diffusing capacity for carbon monoxide have been identified as poor prognosis factors. The treatment relies on usual care for chronic respiratory diseases and is often associated with immunosuppressive and/or antifibrotic therapies. The objective of this classification is to better characterize these patients and improve their management.
auto-immunité; autoimmunity; connective tissue diseases; connectivites indifférenciées; fibrose pulmonaire; interstitial lung diseases; tomodensitométrie; x-ray computed tomography
02
Mars
S0248-8663(24)00059-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

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Ressenti des femmes après traitement prophylactique par héparine de bas poids moléculaire après une césarienne.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38437947
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00083-7
Deruelle P
Debalme C
Garcia-Lebailly K
Giusto CD
Sentilhes L
10.1016/j.gofs.2024.02.027
AbstractText Label OBJECTIVE To assess women's experiences with skin-related side effects following subcutaneous Low Molecular Weight Heparin (LMWH) injections after a cesarean section, and to analyze their impact on treatment adherence. /AbstractText AbstractText Label METHOD A questionnaire was developed in collaboration with Cesarine, a patients' association, to explore various aspects of LMWH administration, including prevention methods, cutaneous side effects, treatment compliance, perceived constraints, apprehension, and understanding of treatment benefits. Additionally, women's opinions on an alternative oral administration approach were solicited, taking into consideration breastfeeding contraindication. The questionnaire was on the Facebook page and blog of the association. /AbstractText AbstractText Label RESULTS 164 women participated in the survey. Among them, 139 women (84.8%) reported bruising, while 117 (71.3%) reported pruritus, erythema, or nodules at the injection site. Treatment discontinuation was observed in 36 cases (22%), decided mostly by the women themselves (77.8%). The main reasons cited for discontinuation were discomfort during injection (71.4%), skin reactions (31;4%), and a perceived lack of effectiveness (54.3%). Furthermore, 88 women (53.7%) wanted to quit the treatment prematurely, citing similar reasons. Thirty-three women (20.1%) reported oversights. For most women, the treatment was perceived as burdensome and caused apprehension. An alternative oral administration method was of interest to 131 women (79.9%). However, only 28 (17.8%) would have accepted if the medication was incompatible with breastfeeding. /AbstractText AbstractText Label CONCLUSION Cutaneous side effects of LMWH injections, as well as injection process itself, have a negative impact on adherence in the postpartum period following a c-section. These findings highlight the need to explore alternative to improve women's compliance and comfort. /AbstractText
caesarean section; césarienne; effets secondaires; phlebitis; phlébite; post-partum; postpartum; prevention; side effects
02
Mars
S2468-7189(24)00083-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Mise en place de consultations pharmaceutiques d’initiation en oncologie digestive dans un centre hospitalo-universitaire : bilan à un an.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38438283
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00043-2
Chapron P
Petit M
Huon JF
Nizet P
10.1016/j.bulcan.2024.01.003
AbstractText Label INTRODUCTION The announcement of a cancer diagnosis is traumatic for the patient. In France, an announcement system has been in place, providing medical time for announcement and treatment proposal, nursing time for support, without including the pharmacist. In order to improve management of patients treated with intravenous anticancer drugs, we set up introductory pharmaceutical consultations in digestive oncology. The aims were to assess the situation one year after the introduction of these consultations, and to assess their contribution. /AbstractText AbstractText Label METHODS When a patient was diagnosed with digestive cancer and receiving intravenous treatment, a pharmaceutical initiation consultation was scheduled. Indicators of activity (number of consultations, average duration, average preparation time and various delays) and results (number and type of pharmaceutical interventions, patient satisfaction) were collected in order to assess activity. /AbstractText AbstractText Label RESULTS Forty-seven pharmaceutical initiation consultations were carried out. The average duration of the consultations was 39.3minutes. Consultations were carried out on average 12.1 days after the medical consultation and 9.6 days before the first chemotherapy treatment. Twenty-nine patients responded to the satisfaction questionnaire. All were satisfied, and the majority of patients said they had improved their knowledge of cancer treatment. /AbstractText AbstractText Label DISCUSSION This activity enables us to review with patients essential aspects of their care, such as implanting an implantable chamber catheter, anti-cancer treatment and managing potential side effects and improve their self-care skills. /AbstractText
4
363-370
111
adverse effects; cancer therapy; consultation pharmaceutique; digestive oncology; effets indésirables; oncologie digestive; patient care; pharmaceutical consultation; soins aux patients; thérapie anticancéreuse
03
Avril
S0007-4551(24)00043-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
antinéoplasiques
préparations pharmaceutiques
humains
oncologie médicale
hôpitaux d'enseignement
antinéoplasiques
orientation vers un spécialiste

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Le taux circulant de PD-L1 : un biomarqueur émergent de réponse aux inhibiteurs de checkpoints immunitaires.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38438284
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00048-1
Chovet F
Passot AS
Mangon Q
Rouzaire P
Dougé A
10.1016/j.bulcan.2023.12.013
Immune checkpoint inhibitors (ICI) have recently become the standard of care for many metastatic solid tumors, with considerable improvements in patient prognosis. However, a non-negligible proportion of patients does not respond to this type of treatment, making it essential to identify predictive factors of this response in order to better adapt the therapy. Among the biomarkers that have been most extensively studied in recent years, tumor PD-L1 levels come out on top, with controversial results for predicting response to ICI. The determination of circulating PD-L1 (or soluble PD-L1) in peripheral blood seems to be an interesting emerging biomarker. Indeed, several studies have investigated its prognostic value, and/or its potential predictive value of response to immunotherapy, and it would appear that there is a correlation between the level of soluble PD-L1 and the level of tumor aggressiveness and therefore prognosis. Furthermore, the results suggest that higher PD-L1 levels are associated with a poorer response to immunotherapy, although this remains to be confirmed in large-scale studies.
4
416-427
111
biomarkers; biomarqueurs; immune checkpoint inhibitors; inhibiteurs de checkpoints immunitaires; pd-l1 soluble; pd-l1 tumoral; solid tumors; soluble pd-l1; tumeurs solides; tumoral pd-l1
03
Avril
S0007-4551(24)00048-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
antigène CD274
marqueurs biologiques tumoraux
humains
tumeurs
pronostic
tumeurs du poumon

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Tumeurs des glandes salivaires : OMS 2022 et au-delà.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38448262
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00046-4
Lépine C
10.1016/j.annpat.2024.02.005
In 2022, the 5th edition of the WHO classification of Head and Neck tumors was published online. In the salivary gland chapter, a new benign entity, the keratocystoma, was introduced. The sclerosing polycystic adenosis has been recognized as tumoral and is now termed sclerosing polycystic adenoma. The striated duct adenoma now has its own dedicated chapter. Additionally, a new variant of pleomorphic adenoma, termed canalicular adenoma-like, has been incorporated. Regarding malignant tumors of the salivary glands, significant doubts now exist regarding the actual existence of oncocytic carcinoma, which has been reclassified among emerging entities. Two new malignant entities have also emerged: microsecretory adenocarcinoma and microcystic sclerosing adenocarcinoma. Finally, primary mucinous adenocarcinoma of the salivary glands has been acknowledged as a distinct entity.
2022 who classification; classification oms 2022; nouveautés; novelties; salivary gland tumors; tumeurs des glandes salivaires
05
Mars
S0242-6498(24)00046-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Tumeur fibromyxoïde ossifiante (TFO) de la joue : une néoplasie distincte des tissus mous.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38448263
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00044-0
Shaker N
Pradhan D
Abu Shakra R
Sangueza OP
10.1016/j.annpat.2024.02.003
05
Mars
S0242-6498(24)00044-0
publication avant impression
Accès restreint
article de périodique

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Un « lâcher de ballons » faussement inquiétant !
2024
http://www.ncbi.nlm.nih.gov/pubmed/38448264
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00049-X
Tauziède-Espariat A
Grand B
Benali A
Georges M
Rialland T
Georges O
10.1016/j.annpat.2024.02.008
05
Mars
S0242-6498(24)00049-X
publication avant impression
Accès restreint
article de périodique

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Léiomyosarcome parotidien en territoire irradié.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38448265
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00048-8
Boullaud L
Bergemer AM
Micaletti F
Periers L
Bakhos D
10.1016/j.annpat.2024.02.007
AbstractText Label INTRODUCTION First case of radiation-induced parotid leiomyosarcoma. /AbstractText AbstractText Label ANATOMO-CLINICAL OBSERVATION A 50-year-old woman with a history of cervical irradiation for Hodgkin's lymphoma presented with a right parotid tumefaction. Examination noted a deep adherent pretragal mass with peripheral facial palsy. A total parotidectomy with intra-operative examination and cervical curage was performed. Histopathological analysis concluded to a grade 3 parotid leiomyosarcoma according to the National Federation of Cancer Centers. Adjuvant radiotherapy was performed. After 24 months of follow-up, the patient presented bone and liver metastases without local recurrence. /AbstractText AbstractText Label DISCUSSION This is the first case of radiation-induced leiomyosarcoma and the 12th case of parotid leiomyosarcoma described in the literature. The management associates surgery with adjuvant radiotherapy. Follow-up is by clinical examination, parotid MRI, and annual thoracoabdominal CT scan to search for metastases. Recurrences occur during the first year in 40 to 64% of cases, and distant metastases in 40 to 60% of cases. The 5-year survival rate is between 10 and 30%. /AbstractText
leiomyosarcoma; léiomyosarcome; parotid gland; parotide; radiation-induced; radio-induit; radiotherapy; radiothérapie
05
Mars
S0242-6498(24)00048-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Un carcinome basocellulaire avec différenciation myoépithéliale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38448266
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00045-2
David C
Taillandier A
Chantreau PL
Kerdraon R
Delalande F
Michenet P
10.1016/j.annpat.2024.02.004
05
Mars
S0242-6498(24)00045-2
publication avant impression
Accès restreint
article de périodique

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Syndrome orbitaire aigu dans le syndrome VEXAS : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38448312
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00073-1
Rimbert N
Retout A
Muraine M
Thorel D
10.1016/j.jfo.2024.104128
104128
05
Mars
S0181-5512(24)00073-1
publication avant impression
Accès restreint
lettre

---
2024
http://www.ncbi.nlm.nih.gov/pubmed/38449386
https://www.cambridge.org/core/product/identifier/S0714980824000096/type/journal_article
Vignolo J
Jacus JP
Darnaud T
Cuervo-Lombard CV
10.1017/S0714980824000096
0,0001).
1-8
alzheimer’s disease; aging; aidants formels; anosognosia; anosognosie; awareness; caregiving; conscience; maladie d’alzheimer; professional caregivers; relation d’aide; vieillissement
07
Mars
S0714980824000096
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Hypoplasie fovéolaire chez un patient atteint du syndrome « morning glory ».
2024
http://www.ncbi.nlm.nih.gov/pubmed/38452597
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00077-9
Lejoyeux R
Landman-Vu J
Atia R
10.1016/j.jfo.2024.104132
4
104132
47
06
Avril
S0181-5512(24)00077-9
publication avant impression
Accès restreint
article de périodique
présentations de cas
humains
troubles de la vision
papille optique
syndrome

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Rétinographies ultra-grand champ montrant une angéite givrée.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38452598
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00070-6
Smiri M
Haddoum KN
Mansouri A
El Sanharawi M
10.1016/j.jfo.2024.104125
4
104125
47
06
Avril
S0181-5512(24)00070-6
publication avant impression
Accès restreint
article de périodique
humains
vascularite rétinienne
vascularite rétinienne
maladies de l'oeil
techniques de diagnostic ophtalmologique
angiographie fluorescéinique
fond de l'oeil

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Filariose oculaire à Loa loa.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38452599
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00069-X
Hasnaoui I
Hazil Z
Krichen MA
Hassina S
Akkenour Y
Serghini L
Elhassan A
10.1016/j.jfo.2024.104124
4
104124
47
06
Avril
S0181-5512(24)00069-X
publication avant impression
Accès restreint
article de périodique
humains
animaux
loase
filarioses
oeil
face
loa

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Analyse des effets des inhibiteurs de l’aromatase en traitement prolongé chez les femmes ménopausées atteintes d’un cancer du sein non métastatique hormonodépendant ayant déjà reçu cinq ans d’hormonothérapie adjuvante : revue systématique et méta-analyse.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38453587
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00051-1
Trenou KC
Mésidor M
Diorio C
Eslami A
Talbot D
10.1016/j.bulcan.2023.12.016
AbstractText Label INTRODUCTION Evaluating the benefits and risks of prolonged hormonal treatment with aromatase inhibitors (AIs) for treating hormone-dependent breast cancer. /AbstractText AbstractText Label METHODS A systematic review and meta-analysis was conducted. Studies reporting on randomized clinical trials concerning prolongating hormonal therapy with AIs as compared to a placebo or no prolongation, after an initial five years of hormonal therapy, were eligible. /AbstractText AbstractText Label RESULTS Seven clinical trials were included. Prolonged AI therapy was associated with a statistically significant improvement in disease-free survival (RR 0.70, 95% CI 0.60 to 0.80). A statistically significant increase was observed for osteoporosis (RR 1.17, 95% CI 1.03 to 1.33), hot flushes/flashes (RR 1.27, 95% CI 1.08 to 1.49), myalgia (RR 1.23, 95% CI 1.09 to 1.39), fractures (RR 1.26, 95% CI 1.09 to 1.45) and arthralgia (RR 1.17, 95% CI 1.10 to 1.25). However, no statistically significant association was observed between prolonged AI therapy and overall survival, cardiovascular events, and bone pain. /AbstractText AbstractText Label DISCUSSION Prolonged AI therapy has significant benefits in terms of disease-free survival in women with hormone-dependent breast cancer. However, adverse effects and a lack of evidence for a benefit on overall survival must be considered in the decision-making process regarding adjuvant hormone therapy extension. /AbstractText
4
356-362
111
aromatase inhibitors; breast neoplasms; cancer du sein; disease-free survival; essai clinique randomisé; inhibiteurs de l’aromatase; randomized clinical trials; survie sans maladie
06
Avril
S0007-4551(24)00051-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
méta-analyse
inhibiteurs de l'aromatase
adjuvants immunologiques
hormones
antinéoplasiques hormonaux
tamoxifène
Femelle
humains
tumeurs du sein
inhibiteurs de l'aromatase
association thérapeutique
traitement médicamenteux adjuvant
adjuvants immunologiques
hormones
antinéoplasiques hormonaux
tamoxifène

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François Gros (1925–2022).
2024
http://www.ncbi.nlm.nih.gov/pubmed/38456447
https://doi.org/10.5802/crbiol.146
Petit C
Kourilsky P
10.5802/crbiol.146
François Gros, a biologist by training, began his research at the Institut Pasteur. In 1961, he discovered the molecular nature of the proposed intermediary between the gene and the protein, a so-called messenger RNA (mRNA), and determined its main characteristics. The author of numerous books, François Gros has helped shape and enlightened the birth of molecular biology and the development of related biotechnologies since the 1970s. He was Professor at the Collège de France and Permanent Secretary of the French Academy of Sciences. Within the Academy, he initiated the creation of a committee for developing countries (COPED). François Gros was a humanist driven by moral rigour and an unfailing sense of commitment.François Gros, biologiste de formation, a débuté ses travaux de recherche à l’Institut Pasteur. En 1961, il découvre la nature moléculaire de l’intermédiaire proposé entre le gène et la protéine, un ARN dit messager (ARNm) et en détermine les principales caractéristiques. À travers la rédaction de nombreux ouvrages, il a accompagné et éclairé de sa réflexion, la naissance de la biologie moléculaire et le développement des biotechnologies associées, à partir des années 1970. Il a été professeur au Collège de France et secrétaire perpétuel de l’Académie des sciences. Il a initié au sein de l’Académie la création d’un comité pour les pays en voie de développement (COPED). François Gros était un humaniste animé d’une rigueur morale et d’un sens de l’engagement sans faille.
S2
3-8
346
françois gros; hommage; notice biographique
29
Mars
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
France
académies et instituts
biographie

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Ophtalmomyiase palpébrale : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38457902
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00054-8
Masson A
Kamoun PD
Malclès A
Eperon G
Massa H
10.1016/j.jfo.2024.104109
4
104109
47
07
Avril
S0181-5512(24)00054-8
publication avant impression
Accès restreint
article de périodique
présentations de cas
animaux
humains
myiases
diptera
paupières
parasitoses oculaires
larve

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Peptides antimicrobiens : une nouvelle alternative pour le traitement des aspergilloses.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38458868
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00141-4
Rochard C
Bigot J
Balloy V
Hennequin C
Guitard J
10.1016/j.rmr.2024.02.011
Aspergillus fumigatus is the predominant fungal species causing pulmonary aspergillosis. The present-day anti-aspergillosis arsenal is limited, with a number of molecules occasioning severe side effects (amphotericin B) or provoking significant drug interactions (azole derivatives). Moreover, the recent emergence of azole-resistant A. fumigatus strains is a cause for concern. In this context, antimicrobial peptides (AMPs) are emerging as a promising therapeutic approach and alternative or complement to conventional antifungals.
4
283-288
41
aspergillus fumigatus; antifongique; antifungal; antimicrobial peptide; aspergillose; aspergillosis; peptide antimicrobien
07
Avril
S0761-8425(24)00141-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
antifongiques
azoles
humains
résistance des champignons aux médicaments
aspergillose
aspergillose
antifongiques
azoles
tests de sensibilité microbienne

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Pembrolizumab en association à la chimiothérapie de première ligne du traitement des adénocarcinomes gastriques ou de la jonction œsogastrique, HER2 négatifs, localement avancés non résécables ou métastatiques.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38458924
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00072-9
Duval M
Zaanan A
10.1016/j.bulcan.2024.01.004
adénocarcinome de la jonction œsogastrique; adénocarcinome gastrique; first-line treatment; gastric adenocarcinoma; gastro-esophageal junction adenocarcinoma; immunotherapy; immunothérapie; maladie métastatique; metastatic disease; première ligne
07
Mars
S0007-4551(24)00072-9
publication avant impression
Accès restreint
lettre

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Talquetamab – myélome multiple en quatrième ligne.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38458925
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00049-3
Fatrara T
Chalayer E
10.1016/j.bulcan.2023.12.014
4
336-337
111
anticorps bispécifique; bispecific antibody; multiple myeloma; myélome multiple; talquetamab
07
Avril
S0007-4551(24)00049-3
publication avant impression
Accès restreint
lettre
anticorps bispécifiques
humains
myélome multiple

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Sacituzumab-govitecan dans les cancers du sein avancés RH HER2– en situation de résistance aux traitements anti-hormonaux et à au moins deux lignes de chimiothérapie en phase avancée.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38458926
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00046-8
Besnainou H
Cabel L
10.1016/j.bulcan.2023.12.011
4
333-334
111
antibody-drug conjugate (adc); anticorps drogue-conjugués (adc); breast cancer; cancer du sein; hormone receptor positive; récepteur hormonal positif (rh ); sacituzumab-govitecan; targeted therapies; thérapies ciblées
07
Avril
S0007-4551(24)00046-8
publication avant impression
Accès restreint
lettre
camptothécine
immunoconjugués
hormones
humains
Femelle
tumeurs du sein
camptothécine
tumeurs du sein triple-négatives

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Quelle connaissance et perception ont les professionnels de santé d’un Centre de lutte contre le cancer à propos des pratiques palliatives encadrées par la loi Claeys-Leonetti : étude PAL PRAT.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38458927
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00044-4
Locatelli M
Flahault C
Roche N
Mateus C
Blot F
Lucile Montalescot
Le Provost JB
Fasse L
10.1016/j.bulcan.2023.12.009
AbstractText Label INTRODUCTION The issue of end-of-life care is the subject of a sensitive debate in French society, particularly regarding the possibility for certain patients to have access to medical assistance in dying. The aim of this study was to assess the knowledge and opinion of healthcare providers on the care practices for patients at the end of life, as well as to highlight any specificities in their discourse. /AbstractText AbstractText Label METHOD A survey of healthcare providers' opinions, composed of closed and open questions, that were analyzed using a lexicometric approach, was distributed in a cancer center. /AbstractText AbstractText Label RESULTS The results of the study reveal a good knowledge of the different procedures. Professionals considered that advance directives should be systematically collected; a majority of them differentiated euthanasia from deep continuous sedation and perceived the latter as a means of relieving patients' suffering without inducing death. The different procedures related to the active assistance in dying were known by a majority of professionals and the survey did not identify a dominant trend concerning the will to practice euthanasia if the legal framework allowed it. Half of the participants considered their training insufficient, indicating the need to fill this gap. /AbstractText AbstractText Label DISCUSSION This survey underlines the importance of training and support for the professionals caring for patients in palliative situation and their relatives in France. /AbstractText
active assistance in dying; aide active à mourir; cancer; deep and continuous sedation until death; euthanasia; euthanasie; healthcare providers; lexicometry; lexicométrie; soignants; sédation profonde et continue jusqu’au décès
07
Mars
S0007-4551(24)00044-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Barrières et facilitateurs à l’activité physique en oncologie en Seine-Saint-Denis : étude qualitative selon l’approche socio-écologique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38458928
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00052-3
Sarreboubee C
Aumaitre A
Labiadh L
Foucaut AM
10.1016/j.bulcan.2023.12.017
AbstractText Label INTRODUCTION Despite the undeniable benefits of physical activity during and beyond cancer treatments, patients do not always undertake and/or maintain it. The aim of the study is to identify, describe and understand the barriers and facilitators of physical activity practice among adults arriving at the end of treatment for solid cancer, in precarious situations, living in Seine-Saint-Denis. /AbstractText AbstractText Label METHODS The study was conducted using a descriptive qualitative phenomenological method involving semi-directed interviews with 23 participants during and beyond cancer. /AbstractText AbstractText Label RESULTS Multiple-level factors (micro, meso, macro) are involved in active behavior of patients. Three main facilitators were identified: perceived benefit, social support, and urban planning. Three barriers are identified: (1) physical and psychological disorders whether or not related to cancer and its treatment, (2) precariousness, organizational constraints, unfavorable social environment, (3) lack of coordination, lack of accurate and appropriate information, lack of realistic referral to physical activity offers. /AbstractText AbstractText Label DISCUSSION A diversity of representations, combinations of factors, and experiences are described. Getting people with cancer to engage in and maintain long-term physical activity is a complex task, requiring multidisciplinary action on all socio-ecological factors. /AbstractText
4
371-383
111
activité physique; barrier; barrière; cancer; exercise; facilitateur; facilitator; modèle socio-écologique; physical activity; precarity; précarité; socio-ecological model
07
Avril
S0007-4551(24)00052-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
adulte
humains
exercice physique
recherche qualitative
soutien social
troubles mentaux
motivation

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Chirurgie bariatrique et médicaments : revue de la littérature et analyse des effets indésirables dans la banque nationale de pharmacovigilance.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38458944
https://linkinghub.elsevier.com/retrieve/pii/S0040-5957(24)00033-7
Nicol C
Jacquot J
Chebane L
Combret S
Pecquet PE
Massy N
Bagheri H
10.1016/j.therap.2024.02.003
AbstractText Label INTRODUCTION ) currently recognized as effective both in achieving tangible and lasting weight loss, and in improving obesity-related comorbidities such as type 2 diabetes, hypertension, and cardiovascular complications. Bariatric surgery, like any other surgery of the digestive tract, can have an impact on nutrient absorption, as well as on drug absorption. The literature on drug management in bariatric surgery patients concerned mainly of case reports and retrospective studies involving a small number of patients. No official guidelines are available. /AbstractText AbstractText Label METHODS We conducted a literature search on the consequences of bariatric surgery in terms of drug bioavailability and/or effect. The Medline (PubMed) database was searched using the following keywords: bariatric surgery, bioavailability, gastric bypass, and obesity. We completed this review with an analysis of reports of adverse drug reactions (ADRs) in post-bariatric surgery patients for obesity registered in the National pharmacovigilance database (PVDB). We selected all cases with the mention of bariatric surgery and/or gastrectomy as medical history. After reading the cases, we excluded those in which the patient had undergone surgery for an indication other than obesity, where the route of administration was other than oral, and cases in which ADRs resulted from voluntary overdose, attempted suicide, allergy, switch to Levothyrox new formulation, meningioma under progestative drugs, inefficacy related to generic substitution and medication error. /AbstractText AbstractText Label RESULTS The literature search identified mainly case report about the impact of bariatric surgery on so-called narrow therapeutic window drugs. We identified 66 informative cases out of a total of 565 cases selected (11%) in the PVDB. Nevertheless, the information does not allow a clear relationship between the occurrence of the ADR and the influence of bariatric surgery. /AbstractText AbstractText Label CONCLUSION There is a lack of official information and/or recommendations on medication use in subjects who have undergone bariatric surgery. Apart from under-reporting, ADRs reports remain largely uninformative. Health professional and patients would be awareness for improving, quantitatively and qualitatively the reporting of ADRs in this population. /AbstractText
adverse drug reactions; bariatric surgery; chirurgie bariatrique; effet indésirable; obese; obèse; pharmacovigilance
24
Février
S0040-5957(24)00033-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Mortalité maternelle en France 2016–2018 : ni tout à fait la même, ni tout à fait une autre.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38460617
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00077-1
Deneux-Tharaux C
Morau E
Dreyfus M
CNEMM
10.1016/j.gofs.2024.02.022
4
173-174
52
confidential enquiry; enquête confidentielle; france; maternal mortality; mortalité maternelle
07
Avril
S2468-7189(24)00077-1
publication avant impression
Accès restreint
article de périodique
rétractation de publication
humains
Femelle
mortalité maternelle
décès maternel
complications de la grossesse
France

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Le plan national fertilité: projet médical ou action politique?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38460618
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00084-9
Allart JB
10.1016/j.gofs.2024.03.001
bioethic law; fertility; fertility national plan
07
Mars
S2468-7189(24)00084-9
publication avant impression
Accès restreint
éditorial

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Anévrisme carotido-ophtalmique révélé par une cécité brutale mimant une occlusion de l’artère centrale de la rétine de l’œil droit : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38461083
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00072-X
Chapron L
Le Pape C
Mouriaux F
10.1016/j.jfo.2024.104127
104127
08
Mars
S0181-5512(24)00072-X
publication avant impression
Accès restreint
lettre

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Le facteur de croissance des nerfs (NGF) dans l’hypertension pulmonaire (HTP).
2024
http://www.ncbi.nlm.nih.gov/pubmed/38461086
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00137-2
Bouchet C
Guibert C
Freund-Michel V
10.1016/j.rmr.2024.02.007
Pulmonary hypertension (PH) is the main pathology in lung circulation, characterized by increased pressure in pulmonary arteries and ultimately resulting in right heart failure with potentially fatal outcomes. Given the current lack of available curative treatments, it is of paramount importance to identify novel therapeutic targets. Due to its involvement in pulmonary arterial remodeling, hyperreactivity, and inflammation, our explorations have focused on the nerve growth factor (NGF), offering promising avenues for innovative therapeutic approaches.
4
265-268
41
circulation pulmonaire; facteur de croissance des nerfs (ngf); hypertension pulmonaire; inflammation; nerve growth factor (ngf); pulmonary circulation; pulmonary hypertension
08
Avril
S0761-8425(24)00137-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
Facteur de croissance nerveuse
humains
hypertension pulmonaire
hypertension pulmonaire
circulation pulmonaire
artère pulmonaire

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Encouragement à l’activité physique adaptée pendant trois mois après la fin des traitements de patients atteints de cancer des VADS : étude interventionnelle pré-post.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38316578
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00006-7
Buiret G
Meniscus L
Riffard G
Caudroit J
10.1016/j.bulcan.2023.11.012
AbstractText Label CONTEXT In our institution, patients with upper aero-digestive tract cancer receive adapted physical activity (APA) awareness training as part of their holistic oncology care program. The main aim of this study was to show that raising awareness of APA helped to increase self-reported PA levels, as assessed by questionnaire. /AbstractText AbstractText Label METHOD This retrospective study included 67 patients with localized Head and Neck cancer. The intervention consisted of an APA teacher; a face-to-face consultation before the start of oncological treatment, four monthly telephone interventions in the three months following the end of treatment. The pre-post evaluation focused on self-reported APA practices before and three months after the end of oncology treatment. /AbstractText AbstractText Label RESULTS APA awareness training significantly increased average total PA, average moderate PA intensity, average weekly walking frequency, average walking intensity, and significantly reduced daily sitting time. The search for correlations between body composition or type of treatments and changes in PA levels showed no significant results. /AbstractText AbstractText Label CONCLUSION This study showed that a basic APA awareness training integrated into a holistic oncology care program could increase patients' self-reported PA levels. The next step will be to verify the objectivity of the increase in self-reported PA, and then to assess its effect on quality of life and survival. /AbstractText
4
384-392
111
activité physique adaptée; adapted physical activity; cancer des voies aérodigestives supérieures; head and neck cancer; soins oncologiques de support; supportive care in cancer
04
Avril
S0007-4551(24)00006-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
qualité de vie
études rétrospectives
exercice physique
marche à pied
tumeurs de la tête et du cou

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Kinésithérapie respiratoire libérale : intérêts et modalités de prescription.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38320877
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(23)00268-1
Proffit M
Magni M
Huck O
Karsandi K
Abdellaoui A
Pichon R
10.1016/j.rmr.2023.10.008
AbstractText Label INTRODUCTION Respiratory diseases represent a major public health issue and impact both quality of life and life expectancy of the patients. /AbstractText AbstractText Label STATE OF ART Several interventions used in respiratory physiotherapy have been shown to reduce dyspnoea, improve quality of life and reduce hospitalisation in many respiratory diseases. However, respiratory physiotherapy remains poorly known to the medical community and may be under-prescribed. /AbstractText AbstractText Label PERSPECTIVES In order to improve the interdisciplinarity around the patient with respiratory impairment, we describe the interests and prescription modalities of liberal respiratory physiotherapy. In the context of respiratory physiotherapy acts, the precision of drafting prescription directly conditions the means implemented by the physiotherapist regarding care provided to the patient. /AbstractText AbstractText Label CONCLUSION The increased knowledge of prescribers, both concerning the prescription methods and the precise content of the rehabilitation sessions is one of the keys to their success. /AbstractText
3
248-256
41
kinésithérapie respiratoire; modalities; modalités; pratique libérale; prescription; private practice; respiratory physiotherapy
05
Mars
S0761-8425(23)00268-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
qualité de vie
techniques de physiothérapie
ordonnances
pratique professionnelle privée
maladies de l'appareil respiratoire

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Corrélations cliniques, morphologiques et génétiques dans les tumeurs mélanocytaires avec translocations chromosomiques.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38320889
Schoelinck J
Pissaloux D
Mouthon M
Vergara R
de la Fouchardière A
10.1016/j.annpat.2024.01.008
In some tumoral subtypes chromosomal translocations lead to an oncogenic chimeric protein acting as a tumorigenesis driver event. The main fusion model combines the promoter swapping of an inactivated tumor suppressor gene and a functional kinase that evades its regulatory system. The range of described fusions keeps growing in the 2023 WHO classification of melanocytic tumours. It is not limited to the group of Spitz tumours as previously but now extends to blue tumours and dermal tumours with a melanocytic phenotype. Molecular pathology helps detect these anomalies using clinical and morphological features. This analysis is essential as this strongly conditions the adapted local treatment of such tumours who are often overtreated.
blue tumour; chromosomal translocation; clear cell tumour; melanocytoma; melanoma; mélanocytome; mélanome; spitz tumour; translocation chromosomique; tumeur bleue; tumeur de spitz; tumeur à cellules claires
05
Février
S0242-6498(24)00031-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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3. Nodule vésiculaire bénin.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38320890
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00028-2
Belleannée G
10.1016/j.annpat.2023.12.014
2
106-107
44
05
Mars
S0242-6498(24)00028-2
publication avant impression
Accès restreint
article de périodique
présentations de cas

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Chronologie de la certification ISO 9001:2015 et enquête de satisfaction au sein du centre d’investigations cliniques plurithématique (CIC-P) de l’historique hôpital Saint-Louis en période de pandémie du COVID-19.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38320894
Ghrieb Z
Walter-Petrich A
Huang J
Chevret S
Montlahuc C
Resche-Rigon M
Kiladjian JJ
Allaoua S
Abdeljalil N
10.1016/j.therap.2023.12.004
The main objectives of multidisciplinary clinical investigation center (CIC-P) are to facilitate the availability of new drugs for patients, to enhance the visibility and attractiveness of French clinical research, to improve the quality of early phase trials, and to enhance the value of academic research by evaluating molecules in rare diseases. Since 2017, the CIC-P has been committed to a quality approach process, launching in 2018 its first satisfaction survey on patient care and clinical trial management of all its employees. A second satisfaction survey targeted by profession type was to be launched in 2020, in view of the requirements of the ISO 9001:2015 standard, but the process was interrupted following the coronavirus diseases 2019 (COVID-19) pandemic. The successful reorganization of the CIC-P activity during the first containment of the COVID-19 pandemic was driven by the implementation of a quality management system that promotes continuous improvement through the organization and involvement of all the staff. This voluntary and participative approach motivated the CIC-P to apply for the organizational sesame. The ISO 9001:2015 certification of CIC-P aims at increasing its performance, to satisfying its customers and to fully integrate its activities in a continuous improvement process, according to the requirements of this international standard, through the deployment of quality tools such as The Deming wheel (PDCA), an indispensable tool for transformation and reorganization; the analysis of the environment by the strengths, weakness, opportunities, threats (SWOT) analysis tool; the analysis and management of risks by the FMEA method, and all with performance indicators (SMART) and precise objectives at each stage of a project/process. The implementation of satisfaction questionnaires remains the essential tool for evaluating the expectations and needs of interested parties, but also for improving the quality of CIC-P activities and services. All these tools put in place have allowed us to continuously improve the means of production and to constantly improve our organization.
covid-19 pandemic; centre d’investigations cliniques plurithématique; certification iso 9001:2015; enquête de satisfaction; hôpital saint-louis; paris; iso 9001:2015 certification; multidisciplinary clinical investigation center; pandémie covid-19; paris; quality management system; smq; saint-louis hospital; satisfaction survey
17
Janvier
S0040-5957(24)00003-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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GPT-4, données de santé et RGPD : l’équation difficile.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38325123
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(24)00016-0
Tahiri Joutei Hassani R
Sandali O
Baudouin C
10.1016/j.jfo.2024.104071
3
104071
47
06
Mars
S0181-5512(24)00016-0
publication avant impression
Accès restreint
éditorial
humains
sécurité informatique

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Néovaisseau fovéolaire pré-rétinien chez une patiente diabétique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38325124
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00571-5
Andoura M
Postelmans L
10.1016/j.jfo.2023.104039
3
104039
47
06
Mars
S0181-5512(23)00571-5
publication avant impression
Accès restreint
article de périodique
Femelle
humains
diabète

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Une pathologie thyroïdienne : la grande simulatrice.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38326138
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00029-4
Senghor F
Hussein Y
Ndiaye K
Slaoui O
Thiam I
Diom ES
10.1016/j.annpat.2024.01.006
AbstractText Label INTRODUCTION Tuberculosis remains a major public health problem in developing countries. Thyroid localization is very rare, and often the cause of misdiagnosis. Pathological anatomy plays an important role in the diagnosis of certainty. The authors report a case of primary thyroid tuberculosis in a 22-year-old patient. We highlight the epidemiological particularities of this case, and discuss diagnostic methods and the contribution of pathological anatomy. /AbstractText AbstractText Label OBSERVATION A 22 year-old male patient, with no reported pathological history, was seen in the clinic for the management of an isolated anterior cervical swelling that had been evolving for two months. Clinical examination revealed only a small thyroid nodule, with no inflammatory or vascular features. Biological tests were unremarkable. Ultrasound revealed a 2.4cm hypoechoic, homogeneous, poorly vascularized tissue mass in the left lobe, classified as EU-TIRADS 3. Fine needle aspiration with cytopathological study revealed a necrotizing granulomatous lesion suggestive of tuberculosis. A lobo-isthmectomy was performed, and histopathology revealed thyroid parenchyma destroyed by tubercular granulomas. The postoperative course was straightforward, with an exeat on postoperative day 6. Anti-tuberculosis treatment was instituted for 6 months. Three- and six-month follow-up examinations were unremarkable. The evolution was favorable, with recovery after treatment. /AbstractText AbstractText Label CONCLUSION Primary thyroid tuberculosis is rare. Cytology is important for orientation, and often helps to avoid misdiagnosis. The diagnosis should be considered in the presence of any thyroid mass in a patient from a tuberculosis-endemic region. /AbstractText
2
125-129
44
anatomie et cytologie pathologiques; pathological anatomy and cytology; thyroïde; tuberculose; tuberculosis; thyroid; ziguinchor
06
Mars
S0242-6498(24)00029-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
Mâle
humains
jeune adulte
adulte
nodule thyroïdien
nodule thyroïdien
thyroïdectomie
cytoponction
tuberculose

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Mise au point diagnostique et prise en charge du pneumothorax spontané idiopathique de l’adolescent.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38326190
Mazenq J
Dubus JC
10.1016/j.rmr.2023.12.002
AbstractText Label INTRODUCTION Due to the absence of consensual definition and agreed-upon pediatric treatment, pneumothorax (PNO) in children and adolescents often remains difficult to properly apprehend. /AbstractText AbstractText Label STATE OF THE ART While initial diagnostic suspicion is clinical, confirmation necessitates chest imaging, and lung ultrasound has become increasingly prevalent, often at the expense of chest radiography. The goal of treatment is twofold, on the one hand to a fully re-expand the lungs, and on the other hand to forestall PNO recurrence. Depending on PNO severity and clinical tolerance, it may be advisable to envision conservative management, oxygen supplementation, needle exsufflation, or chest tube drainage. /AbstractText AbstractText Label PERSPECTIVES In order to harmonize clinical practices, guidelines for the precise definition and graduated management of PNO in children and adolescents are highly advisable. /AbstractText AbstractText Label CONCLUSIONS Idiopathic spontaneous PNO frequently occurs in teenage populations, and its likewise frequent recurrence is not satisfactorily predicted by chest CT findings. It is of paramount importance that patients be fully informed of the risk of recurrence. /AbstractText
2
139-144
41
adolescent; chest tube; drainage; exsufflation; idiopathic spontaneous pneumothorax; pneumothorax spontané idiopathique; thoracoscopie; thoracoscopy
06
Février
S0761-8425(23)00293-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
adolescent
enfant
pneumothorax
pneumothorax
pneumothorax
drainage
drains thoraciques
tomodensitométrie
récidive

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Position de la Société de Pneumologie de Langue Française vis à vis de la nouvelle classification proposée par le groupe GOLD en 2023 : l’accent sur le E.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38326191
Regard L
Deslée G
Zysman M
Le Rouzic O
Roche N
Au nom du Groupe BPCO de la SPLF
10.1016/j.rmr.2024.01.003
2
97-101
41
bpco; copd; classification; exacerbation; fev1; gold; vems
06
Février
S0761-8425(24)00028-7
publication avant impression
Accès restreint
éditorial
humains
broncho-pneumopathie chronique obstructive
troubles respiratoires
maladies de l'appareil respiratoire
maladies de l'appareil respiratoire
langage
Volume expiratoire maximal par seconde
Indice de gravité de la maladie
évolution de la maladie

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Infiltration leucémique bilatérale du nerf optique, première manifestation d’une rechute de leucémie aiguë lymphoblastique : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38330671
Villain P
Bellot L
Mouriaux F
10.1016/j.jfo.2023.104033
2
104033
47
07
Février
S0181-5512(23)00565-X
publication avant impression
Accès restreint
lettre
présentations de cas
humains
nerf optique
leucémie-lymphome lymphoblastique à précurseurs B et T
leucémie-lymphome lymphoblastique à précurseurs B et T
infiltration leucémique
récidive

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