Preferred Label : pharyngeal pouch 4;
Uberon definition : A pharyngeal pouch between pharyngeal arch 4 and arch 5 or 6 (a fifth arch never establishes
in amniotes).;
Uberon synonym : 4th arch branchial pouch endoderm; fourth arch pharyngeal pouch; fourth visceral pouch; fourth branchial pouch; visceral pouch 4; 4th branchial pouch; 4th pharyngeal pouch endoderm; 4th arch branchial pouch; pharyngeal pouches 4;
Uberon related term : fourth pharyngeal pouch;
Uberon Development note : Derivatives include: superior parathyroid glands and ultimobranchial body which forms
the parafollicular C-Cells of the thyroid gland. Musculature and cartilage of larynx
(along with the sixth pharyngeal pouch)[WP] in most mammals, excluding rodents, the
dorsal part of each fourth pouch develops into a superior parathyroid gland (parathyroid
IV), which lies on the dorsal surface of the thyroid gland (the parathyroid glands
derived from the third pouches descend with the thymus and are carried to a more inferior
position than the parathyroid glands that are derived from the fourth pouches); the
elongated ventral part of each fourth pouch develops into the ultimopharyngeal body,
which fuses with the thyroid gland, giving rise to the calcitonin-producing parafollicular
or C-cells of the thyroid gland. In the mouse, but also in the rat and hamster, the
dorsal fourth pouch does not generate a parathyroid. Thus, rodents develop only one
pair of parathyroid glands.;
Uberon Homology note : A conserved feature of all vertebrate embryos is the presence of a series of bulges
on the lateral surface of the head, the pharyngeal arches; it is within these structures
that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid
down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal
pouches.[well established][VHOG];
Origin ID : 0007125;
UMLS CUI : C0231071;
Semantic type(s)
- UMLS correspondences (same concept)
- Uberon cross reference
- develops into
- has part
- part of
A pharyngeal pouch between pharyngeal arch 4 and arch 5 or 6 (a fifth arch never establishes
in amniotes).
