Preferred Label : non-neural ectoderm;
Uberon synonym : non neural ectoderm;
Uberon related term : ventral ectoderm; surface ectoderm;
Uberon narrow term : epidermal ectoderm; epithelial ectoderm;
Uberon Development note : After gastrulation, neural crest cells are specified at the border of the neural plate
and the non-neural ectoderm.;
Uberon Homology note : In the early gastrula of vertebrates, factors from the organizer (e.g. noggin, chordin,
and follistatin in Xenopus) antagonize the epidermalizing factor bone morphogenetic
protein 4 (BMP4), thus dividing the epiblast into neuroectoderm. In Drosophila, decapentaplegic,
the homologue of BMP4, interacts similarly with the protein short gastrulation, the
homologue of chordin. Thus, a comparable molecular mechanism for distinguishing non-neural
ectoderm from neural ectoderm was probably present in the common ancestor of all bilaterally
symmetrical animals.[well established][VHOG];
Origin ID : 0005497;
develops into