Preferred Label : Rathke's pouch;
Uberon definition : A pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum
and gives rise to the anterior and intermediate lobes of the pituitary gland[MP].
In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth
in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary
(adenohypophysis), a part of the endocrine system[WP].;
Uberon synonym : pouch of Rathke; Rathke pouch;
Uberon related term : Rathke's cyst; Rathke's pocket; craniopharyngeal pouch; Rathke's cleft; craniobuccal pouch; pituitary diverticulum; nasohypophyseal pouch; hypophyseal pouch; hypophyseal diverticulum;
Uberon narrow term : adenohypophysial pouch; Rathkes pouch epithelium;
Uberon Homology note : It (the hypophysis) develops embryonically in all vertebrates from two ectodermal
evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon
of the brain, and Rathke's pouch extends dorsally from the roof of the developing
mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon,
which becomes the hypothalamus, and gives rise to the part of the gland known as the
neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in
most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis.
(...) A well-developed hypophyseal system with functional connections to the hypothalamus
is unique to craniates.[well established][VHOG];
Uberon Taxon note : median funnel -shaped invagination of ectoderm, the nasohypophyseal pouch. It will
contribute to the formation of the pituitary gland of the adult lamprey and is homologous
to Rathke's pouch and perhaps to Hatschek 's pit (amphioxus).;
Origin ID : 0005356;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
- develops from
- develops into
- has part
- part of
A pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum
and gives rise to the anterior and intermediate lobes of the pituitary gland[MP].
In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth
in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary
(adenohypophysis), a part of the endocrine system[WP].
