Preferred Label : ventral pancreatic bud;
Uberon definition : pancreatic bud that gives rise to the major pancreatic duct.;
Uberon synonym : pancreas ventral primordium duct bud; pancreas primordium ventral bud;
Uberon related term : ventral pancreatic anlage; anterior pancreatic bud; ventral pancreas anlage; anterior pancreatic anlage;
Uberon Development note : the ventral pancreas and liver are derived from a common precursor cell population[PMID:16417468].
TODO - add this relationship.;
Uberon Homology note : In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from
three buds that emerge from the gut tube, two from its ventral aspect, and one from
its dorsal aspect. In mouse, although there are initially three buds that arise from
the gut tube at the point of contact between the endoderm and the vasculature, the
pancreas develops from only two of these buds, one dorsal and one ventral. (...) In
this study, we use a transgenic zebrafish line (...). We provide evidence for the
existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal
posterior bud - that join to form the definitive pancreas (reference 1); The pancreas
develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula.
In humans, by day 35 of development, the ventral pancreatic bud begins to migrate
backwards and comes into contact and eventually fuses with the dorsal pancreatic bud
during the sixth week of development (reference 2).[well established][VHOG];
Origin ID : 0003924;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
- develops from
- develops into
- part of
pancreatic bud that gives rise to the major pancreatic duct.
