Uberon definition : A duct joining the pancreas to the common bile duct to supply pancreatic juices which
aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the
common bile duct just prior to the ampulla of Vater, after which both ducts perforate
the medial side of the second portion of the duodenum at the major duodenal papilla.;
Uberon synonym : main pancreatic duct; chief pancreatic duct; duct of Wirsung;
Uberon related term : hepaticopancreatic duct; ductus pancreatis ventralis; canal of Wirsung;
Uberon broad term : pancreatic duct;
Uberon Development note : Upon reaching its final destination, the ventral pancreatic bud fuses with the much
larger dorsal pancreatic bud. At this point of fusion, the main ducts of the ventral
and dorsal pancreatic buds fuse, forming the duct of Wirsung, the main pancreatic
duct.;
Uberon Homology note : These data show that ducts within the zebrafish pancreas originally arise in situ
from isolated progenitor cells rather than arising from reiterative branching of the
pancreatic epithelium. This process of pancreatic duct formation in zebrafish may
be analogous to the mechanism of duct formation in the mammalian mammary and salivary
glands. (...) A related mechanism of duct formation has also been proposed to occur
within the mammalian pancreatic epithelium.[uncertain][VHOG];
A duct joining the pancreas to the common bile duct to supply pancreatic juices which
aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the
common bile duct just prior to the ampulla of Vater, after which both ducts perforate
the medial side of the second portion of the duodenum at the major duodenal papilla.